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Protein Alignment Myo10A and jar

DIOPT Version :10

Sequence 1:	NP_001036269.2	Gene:	Myo10A / 32028	FlyBaseID:	FBgn0263705	Length:	3145	Species:	Drosophila melanogaster
Sequence 2:	NP_001014650.2	Gene:	jar / 42889	FlyBaseID:	FBgn0011225	Length:	1268	Species:	Drosophila melanogaster

Alignment Length:	967	Identity:	300/967 - (31%)
Similarity:	443/967 - (45%)	Gaps:	209/967 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 DLGSS--GVEDMTLLDD------LHEASLLWNLRLRYDKGLIYTFAGSILIAVNPYKMFPDAYGL 207
            |:.||  |.:|.   ||      |:||:.|.||:.||.|..|||:..:||||||||:...:.|..
  Fly    48 DIHSSCDGPQDH---DDNCELMLLNEATFLDNLKTRYYKDKIYTYVANILIAVNPYREIKELYAP 109

  Fly   208 EVAKQYAGRPLGSLPPHLFAIGAAAHAALPSPQV------VVISGESGSGKTESTKLVMQYLAAV 266
            :..|:|.||.||.||||:|||   |..|:...:|      :::|||||:|||||||.:::||...
  Fly   110 DTIKKYNGRSLGELPPHVFAI---ADKAIRDMRVYKLSQSIIVSGESGAGKTESTKYLLKYLCYS 171

  Fly   267 VPGGGSASAVITEQILEAAPLLEAFGNARTARNDNSSRFGKYLEVYFKSGA-IVGAKITQYLLEK 330
            ....|.    |..:||:|.|:|||||||:|.||:|||||||::||::.:.. :||..|:.|||||
  Fly   172 HDSAGP----IETKILDANPVLEAFGNAKTTRNNNSSRFGKFIEVHYDAKCQVVGGYISHYLLEK 232

  Fly   331 SRIVTQAPGERNYHVFYELLGGLSETERSKYGLLEADKYFYLNQGATDCASGRVD---------- 385
            |||.||:..||||||||.||.|..:..|.|..|.:.|.|.||:......|:.:.:
  Fly   233 SRICTQSAEERNYHVFYMLLAGAPQQLRDKLSLGKPDDYRYLSGCTQYFANAKTEQLIPGSQKSK 297

  Fly   386 ------------------WESLQGAMQVLGVSEGEREGIVRVLAAVLHLGNVYFHR--RQLRHGQ 430
                              :.:|..|:..||:|:.|:.||..::||||||||:.|..  ..:|.|.
  Fly   298 NHQQKGPLKDPIIDDYQHFHNLDKALGRLGLSDTEKLGIYSLVAAVLHLGNIAFEEIPDDVRGGC 362

  Fly   431 EGVEVGSDAEIKWAAHLLHISADGLHRALTSRTTEA-----RAERLHTPLGIDQALDARDAFAKA 490
            : |...|:..:...:.||.:....|..||.||..::     :...:..||.|.:|.:||||.|||
  Fly   363 Q-VSEASEQSLTITSGLLGVDQTELRTALVSRVMQSKGGGFKGTVIMVPLKIYEASNARDALAKA 426

  Fly   491 LYAGLFNWLVSRINSIVQKGGTHDAHRISILDIFGFEDLAENSFEQLCINYANENLQLYFNKHVF 555
            :|:.||:.:|..||..:....::  ..|.:|||.|||....|||||.||||.||.||.:||.::.
  Fly   427 IYSRLFDRIVGLINQSIPFQASN--FYIGVLDIAGFEYFTVNSFEQFCINYCNEKLQKFFNDNIL 489

  Fly   556 KLEQAEYARERLEWTPLAWDDNLPVIHLLAKKPVGICHLLDDESNFPRATDLSFLEKCH---YNH 617
            |.||..|.||.|....:.:.||..:|.|:..|..||..|||:||..|:.:...|..:.|   .||
  Fly   490 KNEQELYKREGLNVPEITFTDNQDIIELIEAKSNGIFTLLDEESKLPKPSYSHFTAEVHKSWANH 554

  Fly   618 ------ALSELYARPRIGAQE-FGVTHYAGQVWYCVDGFLDKNRDALRGDVLELLASSRLPLVGE 675
                  ..|.|.|...:..:| |.|.|:||.|.|..:.|::||.|||...:..|:.....||:..
  Fly   555 YRLGLPRSSRLKAHRTLRDEEGFLVRHFAGAVCYNTEQFIEKNNDALHASLEGLVQECDNPLLQT 619

  Fly   676 LTKQLRAQRDAGKTLPKGSNGRFVTMKPRTPTVAARFADSLQQLLQSMGRCHPWFVRCIKPNQEK 740
            |             .|.||: ..|..|....:|.::|...|.:|::.:.:....|:||||||.:.
  Fly   620 L-------------FPSGSS-TSVRGKLNFISVGSKFKTQLGELMEKLEQNGTNFIRCIKPNSKM 670

  Fly   741 HALRMDMPCVLQQLRYLGMLDTIQIRQRGYPVRLRFQHFVERYRHLLPSPLARGTPYRELCRALL 805
            ...:.:....|.||:..|.:..:::.:.|||.|:.|......|:.:||..|. ..|.|..|.|:.
  Fly   671 IDRQFEGSLALAQLKCSGTISVLELMEHGYPSRVLFADLYSMYKSVLPPELV-SLPARTFCEAMF 734

  Fly   806 EAMPRTGVEGPDYQLGATRVFLREA----LHRALESGRTERL----------------------- 843
            :::   .:...|::.|.|:||.|..    ..|.:.|.....|
  Fly   735 QSL---NLSAKDFKFGITKVFFRPGKFVEFDRIMRSDPENMLAIVAKVKKWLIRSRWVKSALGAL 796

  Fly   844 ------------RRAAVSVQRHVRGMLVRRQ---------------------------------- 862
                        .:..:..||..||.|.|:|
  Fly   797 CVIKLRNRIIYRNKCVLIAQRIARGFLARKQHRPRYQGIGKINKIRTNTLKTIEIASGLKMGREE 861

  Fly   863 -------------------------------------LARRQAAATRLQARWRGQRAQQRYERLR 890
                                                 :|........|..:.:.|:..:..||||
  Fly   862 IISGVNDIYRQIDDAIKKIKMNPRITQREMDSMYTVVMANMNKLTVDLNTKLKEQQQAEEQERLR 926

  Fly   891 K--GALTAQRLWRGRQARRRVQQ-----LRSDHRRRQEAREAAQRAREAREAKQAVL 940
            |  .||.|:|..:..:.:|:.::     |:::...|::|.| |||.|:..|.::|.|
  Fly   927 KIQEALEAERAAKEAEEQRQREEIENKRLKAEMETRRKAAE-AQRLRQEEEDRRAAL 982

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.