Protein Alignment Myo10A and Prm

DIOPT Version :9

• Sequence 1: NP_001036269.2
• Gene: Myo10A / 32028
• FlyBaseID: FBgn0263705
• Length: 3145
• Species: Drosophila melanogaster
• Sequence 2: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Alignment Length: 937
• Identity: 142/937 - (15%)
• Similarity: 302/937 - (32%)
• Gaps: 270/937 - (28%)

  Fly  1743 DEPQFQTEEDFFAFKMRQHQRKTTPQAQHHQMTSNGGMMESGPGARGASATAIEWEEFE----IE 1803
            ::...::||.....|.:.::..|..|.|...:|.|....|.       .....:.|.:|    ||
  Fly   108 EDVHLESEETTLLLKKKHNEIITDFQEQVEILTKNKARAEK-------DKAKFQTEVYELLSQIE 165

  Fly  1804 SPTPPPMSGQ---------LMRSSIRLETTTTTTTSAVNNRDRDRETQDVGQPMQSVVTTKLAKK 1859
            |.....:..:         :...::::|....|.....::|.|                  |:::
  Fly   166 SYNKEKIVSEKHISKLEVSISELNVKIEELNRTVIDISSHRSR------------------LSQE 212

  Fly  1860 SFEIGADRPPPGSVGKLKLSSEMRQRLEQVTAGHSVRSTVSTKSEQRAPAKLEDTRKLMLQQQLG 1924
            :.|:..|      |..||:..:        |...|....:|...:.|...:.||.|:.:|:..|.
  Fly   213 NIELTKD------VQDLKVQLD--------TVSFSKSQVISQLEDARRRLEDEDRRRSLLESSLH 263

  Fly  1925 GLFASVSGGNSGPGGVVDSHATVRTQIERMEGKLSPPPAPPSGGWPGVLLPPAPSVPAPPPPIRP 1989
            .:...:....:    .::..:..|..:||...|.:.........|
  Fly   264 QVEIELDSVRN----QLEEESEARIDLERQLVKANADATSWQNKW-------------------- 304

  Fly  1990 PSMAPPAPPPAPQSPPTARSPEPEPDYRTSSSQV--VKEHVPAFI-------------------- 2032
                        .|...||:.|.|...|....::  ::||:.:.|
  Fly   305 ------------NSEVAARAEEVEEIRRKYQVRITELEEHIESLIVKVNNLEKMKTRLASEVEVL 357

  Fly  2033 ----QRQERDTFGAVRQQQMISSHHLHLE---------------DHSASSSPAVAAWEQAERERS 2078
                ::.........:....:..|::.|:               |.....:..|....:.::.:.
  Fly   358 IIDLEKSNNSCRELTKSVNTLEKHNVELKSRLDETIILYETSQRDLKNKHADLVRTVHELDKVKD 422

  Fly  2079 RSRSRSRDREDYSESVWDRAEVEGPASGSGSEKEREKRERERERLYEIRQVERERESHKVYQPAP 2143
            .:...:|:.:...:.:.:       |.|:.:|..|...|.|    .|:|::|.||:
  Fly   423 NNNQLTRENKKLGDDLHE-------AKGAINELNRRLHELE----LELRRLENERD--------- 467

  Fly  2144 PRVIQASMDTTGGHRREDRTGG--LATFRTHMAQKYEHERKRKSSASSGMREELDSMHMTTPPPV 2206
             .:..|..:...|.:.|::.|.  .|.|     .:|.|:.:|:.:...   ||::::...|...:
  Fly   468 -ELTAAYKEAEAGRKAEEQRGQRLAADF-----NQYRHDAERRLAEKD---EEIEAIRKQTSIEI 523

  Fly  2207 ------IVPAPVPPPSSTSPGLGVVSGVLMGSGSGGSTACLTYNRVPWKLRVRKEVFQPHEPIGP 2265
                  ::.|.....:..:                         |:..||:::....:....:..
  Fly   524 EQLNARVIEAETRLKTEVT-------------------------RIKKKLQIQITELEMSLDVAN 563

  Fly  2266 PVALDLLFAQVLGDVFGVTPCLRITPQEKSSALNMLHGHGVSVD-----TLSNRNGSGAGGGGNG 2325
            ...:||  .:|:              :::|..|..|..|...|.     ||.....:.....|..
  Fly   564 KTNIDL--QKVI--------------KKQSLQLTELQAHYEDVQRQLQATLDQYAVAQRRLAGLN 612

  Fly  2326 GQVRALVKRHLVDMARDWPLYFARLFAVQGAPLYPDVSIMGVSHSGLYLARRDADYLIVVQAISF 2390
            |::.. |:.||....|     ..|...:|.......::.:..::..|...:...:..:.|.|..:
  Fly   613 GELEE-VRSHLDSANR-----AKRTVELQYEEAASRINELTTANVSLVSIKSKLEQELSVVASDY 671

  Fly  2391 GEIQSAVTLPRPAALQLNLRNGKHLALHAARAAAIQSMVTTFVQEFRKSQS---KASTLSSGARA 2452
            .|:                  .|.|.:...|...:|..:...|::..:.|.   |..|:......
  Fly   672 EEV------------------SKELRISDERYQKVQVELKHVVEQVHEEQERIVKLETIKKSLEV 718

  Fly  2453 AAQTLNVPLERLE-SRQAHAQRNEHGVDGGSRQNEQLQQSELHHH------LQQQQQQQQQ--QQ 2508
            ..:.|::.||.:| :..|.::|....::...|..|...:.|...|      |:::::..::  .|
  Fly   719 EVKNLSIRLEEVELNAVAGSKRIISKLEARIRDLELELEEEKRRHAETIKILRKKERTVKEVLVQ 783

  Fly  2509 HHQQQQQQQQLEDAMEEQHMATDHQQQQQQQLGQQQGQQQ-------RFLKQ-----------QS 2555
            ..:.|:....|:||:::   :|......::||.:|:|..|       ||.::           :|
  Fly   784 CEEDQKNLILLQDALDK---STAKINIYRRQLSEQEGVSQQTTTRVRRFQRELEAAEDRADTAES 845

  Fly  2556 YLHSAR-KSNAGQQPSSLTNGQVHHQE 2581
            .|:..| |.......|::...||:.||
  Fly   846 SLNIIRAKHRTFVTTSTVPGSQVYIQE 872

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo10A	NP_001036269.2	MYSc	156..836	CDD:214580
		MYSc_Myo15	169..828	CDD:276838
		MyTH4	1014..1171	CDD:295320
		MyTH4	2704..2810	CDD:279165
		B41	2823..3033	CDD:214604
		FERM_B-lobe	2920..3025	CDD:271216
		FERM_C_MyoXV	3029..3138	CDD:270022
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:279860	136/916 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466286
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840