Protein Alignment Myo10A and Myo31DF

DIOPT Version :10

• Sequence 1: NP_001036269.2
• Gene: Myo10A / 32028
• FlyBaseID: FBgn0263705
• Length: 3145
• Species: Drosophila melanogaster
• Sequence 2: NP_523538.1
• Gene: Myo31DF / 34445
• FlyBaseID: FBgn0086347
• Length: 1011
• Species: Drosophila melanogaster
• Alignment Length: 891
• Identity: 297/891 - (33%)
• Similarity: 437/891 - (49%)
• Gaps: 134/891 - (15%)

  Fly   155 SGVEDMTLLDDLHEASLLWNLRLRYDKGLIYTFAGSILIAVNPYKMFPDAYGLEVAKQYAGRPLG 219
            :||:|..|||.:.....:.|||.|:..|.|||:.|.:.:::|||:.. :.||.|..::|.||.|.
  Fly     7 AGVQDFVLLDQVSMEKFMDNLRKRFQNGSIYTYIGEVCVSMNPYRQM-NIYGPETIRKYKGRELF 70

  Fly   220 SLPPHLFAIGAAAHAALPSPQ---VVVISGESGSGKTESTKLVMQYLAAVVPGGGSASAVITEQI 281
            ...||||||..:|:..|...|   .::||||||:||||::|::|:|:|||....|.......:.:
  Fly    71 ENAPHLFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMKYIAAVTNAQGQNEIERVKNV 135

  Fly   282 L-EAAPLLEAFGNARTARNDNSSRFGKYLEVYFKSGA-IVGAKITQYLLEKSRIVTQAPGERNYH 344
            | ::..:||.||||:|.|||||||||||:::.|...| .||..||.|||||||:|.|.|||||:|
  Fly   136 LIQSNAILETFGNAKTNRNDNSSRFGKYMDIEFDYKADPVGGIITNYLLEKSRVVQQQPGERNFH 200

  Fly   345 VFYELLGGLSETERSKYGL-LEADKYFYLNQGATDCASGRVDWESLQGAMQVLGVSEGEREGIVR 408
            .||:||.|.::.|..:|.| .|..||.|||||:.|..:.:.|::....|.:.||.|..|.:.|.|
  Fly   201 SFYQLLRGANDNELRQYELQKETGKYHYLNQGSMDILTEKSDYKGTCNAFKTLGFSTDEVQTIWR 265

  Fly   409 VLAAVLHLGNVYFHRRQLRHGQEGVEVGSDAEIKWAAHLLHISADGLHRALTSRTTEARAERLHT 473
            .:|||||||||.|...     ::.:.:.:...:|..|.||.::...|..|||.|...|....:..
  Fly   266 TIAAVLHLGNVEFQTI-----EDELVISNKQHLKSTAKLLQVTETELSTALTKRVIAAGGNVMQK 325

  Fly   474 PLGIDQALDARDAFAKALYAGLFNWLVSRINSIVQKGGTHDAHR----ISILDIFGFEDLAENSF 534
            .....||...:||.|||:|..||.|::||||..:...|:....|    |.:|||:|||....|||
  Fly   326 DHNATQAEYGKDALAKAIYDRLFTWIISRINRAILFRGSKTQARFNSVIGVLDIYGFEIFDSNSF 390

  Fly   535 EQLCINYANENLQLYFNKHVFKLEQAEYARERLEWTPLAWDDNLPVIHLLAKKPVGICHLLDD-- 597
            ||.||||.||.||..|.:.|.|.||.||.||.:|||.:.:.:|..:..|:.:...||..::|:
  Fly   391 EQFCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEYFNNKIICDLVEQPHKGIIAIMDEAC 455

  Fly   598 -------ESNFPRATDLSFLEKCHYNHAL-----SELYARPRIGAQEFGVTHYAGQVWYCVDGFL 650
                   :.....|.|.:..:..||....     .||..|     ::|.:|||||.|.|.::||:
  Fly   456 LSVGKVTDDTLLGAMDKNLSKHPHYTSRQLKPTDKELKHR-----EDFRITHYAGDVIYNINGFI 515

  Fly   651 DKNRDALRGDVLELLASSRLPLVGELTKQLRAQRDAGKTLPKGSNGRFVTMKPRTPTVAARFADS 715
            :||:|.|..|...||.:|:...:.|:             .|:|:.....|.| |..|....|..|
  Fly   516 EKNKDTLYQDFKRLLHNSKDANLSEM-------------WPEGAQDIKKTTK-RPLTAGTLFQRS 566

  Fly   716 LQQLLQSMGRCHPWFVRCIKPNQEKHALRMDMPCVLQQLRYLGMLDTIQIRQRGYPVRLRFQHFV 780
            :..|:.::.:..|::|||||||..|.:...|...|..|:||||:|:.:::|:.|:..|.|:..|:
  Fly   567 MADLVVTLLKKEPFYVRCIKPNDLKSSTVFDEERVEHQVRYLGLLENLRVRRAGFVHRQRYDKFL 631

  Fly   781 ERYRHL--LPSPLARGTPYRELCRALLEAMPRTGVEGPDYQLGATRVFLREALHR-ALESGRTER 842
            .||:.:  ...|..|....|:..|.|:|...    ...|.:.|.|::|:|..... |||..|.|.
  Fly   632 LRYKMISQYTWPNFRAGSDRDGVRVLIEEKK----FAQDVKYGHTKIFIRSPRTLFALEHQRNEM 692

  Fly   843 LRRAAVSVQRHVRGMLVRRQLARRQAAATRLQARWRGQRAQQRYERLRKGALTAQRLWRGRQARR 907
            :......:|:.|||.:|||...:                        .|.|:|..|.::..:.|.
  Fly   693 IPHIVTLLQKRVRGWIVRRNFKK------------------------MKAAITIVRAYKAYKLRS 733

  Fly   908 RVQQLRSDHRRRQEAREAAQRAREAREAKQAVLERSQLSYLDIPAELAFIYSKLQGWSPPHGDRH 972
            .||:|             |.|.|:|::.:.                    |.|...|
  Fly   734 YVQEL-------------ANRLRKAKQMRD--------------------YGKSIQW-------- 757

  Fly   973 LVKVLGTVPGPPSSAVQLPEDLGQ-FSFGKFSSVYCNGLRLQPRRE 1017
                    |.||.:..::...|.: |.|.:.:.:    |...||.|
  Fly   758 --------PQPPLAGRKVEAKLHRMFDFWRANMI----LHKYPRSE 791

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo10A	NP_001036269.2	MYSc_Myo15	169..828	CDD:276838	253/684 (37%)
		PTZ00121	<828..>943	CDD:173412	25/115 (22%)
		MyTH4	1014..1171	CDD:470587	3/4 (75%)
		Ubl1_cv_Nsp3_N-like	1178..>1245	CDD:475130
		MyTH4	2704..2810	CDD:459939
		FERM_B-lobe	2920..3025	CDD:271216
		FERM_C_MyoXV	3029..3138	CDD:270022
Myo31DF	NP_523538.1	MYSc_Myo1	21..677	CDD:276829	253/684 (37%)
		Myosin_TH1	801..977	CDD:461801