Protein Alignment Myo10A and CG31638

DIOPT Version :9

• Sequence 1: NP_001036269.2
• Gene: Myo10A / 32028
• FlyBaseID: FBgn0263705
• Length: 3145
• Species: Drosophila melanogaster
• Sequence 2: NP_723186.2
• Gene: CG31638 / 33910
• FlyBaseID: FBgn0051638
• Length: 704
• Species: Drosophila melanogaster
• Alignment Length: 693
• Identity: 123/693 - (17%)
• Similarity: 206/693 - (29%)
• Gaps: 298/693 - (43%)

  Fly  2013 EPDYRTSSSQVVKEHVPAFIQRQERDTFGAVR---QQQMISSHHL------------HLEDHSAS 2062
            :.:.|::..:.|:|.:.  :|.|.|.....|.   |:::.:..:|            ||:..:||
  Fly   281 QEEMRSAKQEAVRELLT--LQEQHRAEMRIVNNSLQEEIAARENLERRLTELRTELEHLQAENAS 343

  Fly  2063 SSPAVAAWEQAERERSRSRSRSRDRE-------DYSESVWDRAEVEGPASGSGSEKEREKRERER 2120
            .      |.:.||..|...:..||.:       ||.|    |::.:.....:...:.|..::...
  Fly   344 E------WGKRERLESEKLAMERDNKKLRAELRDYQE----RSDRKCRPMQANDVELRALQQELS 398

  Fly  2121 ERLYEIRQVERERESHKVYQPAPPRVIQASMDTTGGH--RREDRTGGLATFRTHMAQKYEHERKR 2183
            ||..||.:|   :.||     |..:.:.|..:|..||  ||              |::||.|.||
  Fly   399 ERNKEISEV---KMSH-----AKLKKLLAETNTELGHAVRR--------------AEQYEAEVKR 441

  Fly  2184 KSSASSGMREELDSMHMTTPPPVIVPAPVPPPSSTSPGLGVVSGVLMGSGSGGSTACLTYNRVPW 2248
                                                                             
  Fly   442 ----------------------------------------------------------------- 441

  Fly  2249 KLRVRKEVFQPHEPIGPPVALDLLFAQVLGDVFGVTPCLRITPQEKSSALNMLHGHGVSVDTLSN 2313
             ||.|.|..: .|..|....||....||           |...:.....:....|..|.:..|.|
  Fly   442 -LRQRVEELK-RELAGAEDELDSAVNQV-----------RRLQRSNDELVGQTEGLQVQIQHLQN 493

  Fly  2314 RNGSGAGGGGNGG-QVRALVKRHLVDMARDWPLYFARLFAVQGAPLYPDVS----IMGVSHSGLY 2373
            |........|.|| |:|   .:..|::..|               ..|:::    |...|.:||
  Fly   494 RRAPSPQLRGMGGVQLR---NKIAVELPND---------------CLPNINDLRQIFDDSQAGL- 539

  Fly  2374 LARRDADYLIVVQAISFGEIQSAVTLPRPAALQLNLRNGKHLALHAARAAAIQSMVTTFVQEFRK 2438
                                             .:..||...|:|  .||:::....|.....::
  Fly   540 ---------------------------------RSSHNGSDAAMH--HAASVKRSSHTERTLLQQ 569

  Fly  2439 SQSKASTLSSGARAAAQTLNVPLERLESRQAHAQRNEHGVDGGSRQNEQLQQSELHHHLQQQQQQ 2503
            .||.|:..::.|.|||...      .:::..|.:.|   :.....:|.:.:::       :|:..
  Fly   570 QQSSAAASAAAAAAAAAAF------FDAKPTHLEEN---IFESKSRNLEFERA-------KQKFD 618

  Fly  2504 QQQQQHHQQQQQQQQLEDAMEEQHMATDHQQQQQQQLGQQQGQQQRFLKQQSYLHSARKSNAGQQ 2568
            ....|||.                    |.|:|:...|                   |..:||..
  Fly   619 NPHGQHHH--------------------HHQRQRSGNG-------------------RYGSAGSS 644

  Fly  2569 PSSLTNGQVHHQEQMLQQQQQQSQSLPHHDLDANYLQDESNGGTPPSVTKYSLLQFAMQHFRNDQ 2633
            .|                  :.:.:||        |:..:|||:....:|..|         |.|
  Fly   645 AS------------------RANLALP--------LKGTTNGGSSSVSSKDEL---------NRQ 674

  Fly  2634 LRDADRHHERHQSAANRSYAELVKWQGHAIRLPLLRLPNDLAP 2676
            |      :|:.|| |...||.      ::|.|..|::.:|..|
  Fly   675 L------YEKEQS-AGAGYAR------NSINLDGLKVSDDETP 704

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo10A	NP_001036269.2	MYSc	156..836	CDD:214580
		MYSc_Myo15	169..828	CDD:276838
		MyTH4	1014..1171	CDD:295320
		MyTH4	2704..2810	CDD:279165
		B41	2823..3033	CDD:214604
		FERM_B-lobe	2920..3025	CDD:271216
		FERM_C_MyoXV	3029..3138	CDD:270022
CG31638	NP_723186.2	DUF4201	284..457	CDD:290581	50/273 (18%)
		Ax_dynein_light	<300..369	CDD:287215	15/74 (20%)
		RILP-like	<312..448	CDD:304877	40/233 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466290
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930