Protein Alignment Myo10A and Myo1g

DIOPT Version :10

• Sequence 1: NP_001036269.2
• Gene: Myo10A / 32028
• FlyBaseID: FBgn0263705
• Length: 3145
• Species: Drosophila melanogaster
• Sequence 2: NP_001423969.1
• Gene: Myo1g / 289785
• RGDID: 1306016
• Length: 1018
• Species: Rattus norvegicus
• Alignment Length: 1014
• Identity: 345/1014 - (34%)
• Similarity: 496/1014 - (48%)
• Gaps: 173/1014 - (17%)

  Fly   156 GVEDMTLLDDLHEASLLWNLRLRYDKGLIYTFAGSILIAVNPYKMFPDAYGLEVAKQYAGRPLGS 220
            |..|..|||.|.....:.||:||::||.|||:.|.:|::||||:..| .||.|...:|.||.|..
  Rat    10 GKPDFVLLDQLTMEEFMKNLQLRFEKGRIYTYIGEVLVSVNPYQELP-LYGPEAIAKYQGRELYE 73

  Fly   221 LPPHLFAIGAAAHAAL---PSPQVVVISGESGSGKTESTKLVMQYLAAVV-PGGGSASAVITEQI 281
            .||||:|:..||:.|:   .....:|||||||:||||::|.:|||:|||. |...:....:.:.:
  Rat    74 RPPHLYAVANAAYKAMKRRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQRAEVERVKDVL 138

  Fly   282 LEAAPLLEAFGNARTARNDNSSRFGKYLEVYFK-SGAIVGAKITQYLLEKSRIVTQAPGERNYHV 345
            |::..:|||||||||.||.||||||||:::.|. .|..||..|..|||||||::.|..||||:|.
  Rat   139 LKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPVGGHIHSYLLEKSRVLKQHVGERNFHA 203

  Fly   346 FYELLGGLSETERSKYGLLEADKYFY--------LNQGATDCASGRVDWESLQG---AMQVLGVS 399
            ||:||.| ||.:..:...||.:...|        ||.|..:....  |.:|.||   ||:::|.|
  Rat   204 FYQLLRG-SEDQELQELHLERNPAVYNFTRQGAGLNMGVHNALGS--DEKSHQGVMEAMKIIGFS 265

  Fly   400 EGEREGIVRVLAAVLHLGNVYFHRRQLRHGQE-GVEVGSDAEIKWAAHLLHISADGLHRALTSRT 463
            ..|.|.|.|:|||:|||||:.|...:....|: |:||..:|.:.:.|.|....:|.:.|.|.:||
  Rat   266 PEEVESIHRILAAILHLGNIEFVETEENGPQKGGLEVADEALVGYVAKLTATPSDLVLRTLLART 330

  Fly   464 TEARA----ERLHTPLGIDQALDARDAFAKALYAGLFNWLVSRINSIVQKGGTHDAHR------I 518
            ..:..    |:.||   :.:|..||||.|||:|..||.|:|::||||::. ...|..|      |
  Rat   331 VASGGREVIEKSHT---VAEASYARDACAKAMYQRLFEWVVNKINSIMEP-RDRDPRRDGKDTVI 391

  Fly   519 SILDIFGFEDLAENSFEQLCINYANENLQLYFNKHVFKLEQAEYARERLEWTPLAWDDNLPVIHL 583
            .:|||:|||....|||||.||||.||.||..|.:.:.|.||.||.||.:.|..:.:.:|..::.|
  Rat   392 GVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQLILKQEQEEYEREGITWQSIEYFNNATIVEL 456

  Fly   584 LAKKPVGICHLLDDE-SNFPRATDLSFLEKCHYNHALSELYAR----PRIGAQEFG----VTHYA 639
            :.:...||..:||:. |.....||..||:....:|.....|:.    |.....|||    :.|||
  Rat   457 VEQPRRGILAVLDEACSTAGPITDRIFLQTLDTHHRHHPHYSSRQLCPTDKTMEFGRDFQIKHYA 521

  Fly   640 GQVWYCVDGFLDKNRDALRGDVLELLASSRLPLVGELTKQLRA-----QRDAGKTLPKGSNGRFV 699
            |.|.|.|:||:|||||:|..|...||.:|..|       .|||     |:|..:          |
  Rat   522 GDVTYSVEGFIDKNRDSLFQDFKRLLYNSMDP-------TLRAMWPDGQQDITE----------V 569

  Fly   700 TMKPRTPTVAARFADSLQQLLQSMGRCHPWFVRCIKPNQEKHALRMDMPCVLQQLRYLGMLDTIQ 764
            |.:|.  |....|.:|:..|::::....|::|||||||::|...|:|......|:.|||:|:.::
  Rat   570 TKRPL--TAGTLFKNSMIALVENLASKEPFYVRCIKPNEDKVPGRLDEAHCRHQVEYLGLLENVR 632

  Fly   765 IRQRGYPVRLRFQHFVERYR---------HLLPSPLARGTPYRELCRALLEAMPRTGVEGPDYQL 820
            :|:.|:..|..:..|:.||:         |||.|.       ||...||||   :.|::| |...
  Rat   633 VRRAGFASRQPYPRFLLRYKMTCEYTWPNHLLGSD-------REAVSALLE---QHGLQG-DVAF 686

  Fly   821 GATRVFLREALHRALESGRTERLRRAAVSVQR---HVRGMLVRRQLARRQAAATRLQARWRGQRA 882
            |.:::|:|..              |..|::::   |:..::|           ..||..|||..|
  Rat   687 GHSKLFIRSP--------------RTLVTLEQSRAHLIPIIV-----------LLLQKAWRGTLA 726

  Fly   883 QQRYERLRKGALTAQRLWRGRQARRRVQQLRSDHRRRQEAREAAQRARE-AREAKQAVLERSQLS 946
            :.|..||| ...|....:|..:.|..:.:|:   ||.|.||:.....|: ......|||:..|
  Rat   727 RWRCRRLR-AIYTIMGWFRRHKVRAHLIELQ---RRFQAARQPPLYGRDLVWPTPPAVLQPFQ-- 785

  Fly   947 YLDIPAELAFIYSKLQGWSPPHGDRHLVKVLGTVPGPPSSAVQLPEDLGQFSFGKFSSV------ 1005
                 .....::|:   |..    |.|||.:     |||...|:...:.  :.|....:
  Rat   786 -----DTCHILFSR---WRA----RQLVKNI-----PPSDMTQIKAKVA--AMGALQGLRQDWGC 831

  Fly  1006 -------YCNGLRLQPRREPITAPLLTRAASRDQD-FQDALAVFKLILRWSN------DKALEGA 1056
                   |.:.....|....:.|..|  .|.|::| |...|  |...:|..|      |:||
  Rat   832 QRAWARDYLSSDTDNPTASHLFAEQL--KALREKDGFGTVL--FSSHVRKVNRFRKRRDRAL--- 889

  Fly  1057 KEKLLADYIVHKALSSRGLRDEILVQLCNQVHGLPPNSG 1095
               ||.|..::|....|..|....|.| :.|.||...||
  Rat   890 ---LLTDRHLYKLEPGRQYRVMRAVPL-DAVTGLSVTSG 924

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo10A	NP_001036269.2	MYSc_Myo15	169..828	CDD:276838	271/708 (38%)
		PTZ00121	<828..>943	CDD:173412	28/118 (24%)
		MyTH4	1014..1171	CDD:470587	27/89 (30%)
		Ubl1_cv_Nsp3_N-like	1178..>1245	CDD:475130
		MyTH4	2704..2810	CDD:459939
		FERM_B-lobe	2920..3025	CDD:271216
		FERM_C_MyoXV	3029..3138	CDD:270022
Myo1g	NP_001423969.1	None