Protein Alignment Myo10A and Myo31DF

DIOPT Version :10

• Sequence 1: NP_001036269.2
• Gene: Myo10A / 32028
• FlyBaseID: FBgn0263705
• Length: 3145
• Species: Drosophila melanogaster
• Sequence 2: XP_061516868.1
• Gene: Myo31DF / 1279578
• VectorBaseID: AGAMI1_012998
• Length: 1025
• Species: Anopheles gambiae
• Alignment Length: 1004
• Identity: 327/1004 - (32%)
• Similarity: 489/1004 - (48%)
• Gaps: 158/1004 - (15%)

  Fly   156 GVEDMTLLDDLHEASLLWNLRLRYDKGLIYTFAGSILIAVNPYKMFPDAYGLEVAKQYAGRPLGS 220
            ||:|..|||.:.:...:.||:.|:..|.|||:.|.:.|:||||:.. :.||.|...:|.||.|..
Mosquito    10 GVQDFVLLDAVTQDKFMDNLKRRFQAGKIYTYIGEVCISVNPYREM-NIYGPEYVNRYKGRELFE 73

  Fly   221 LPPHLFAIGAAAHAALP---SPQVVVISGESGSGKTESTKLVMQYLAAVVPGGGSASAVITEQIL 282
            ..||:|||..||:..|.   :...::||||||:||||::|::|:|:|||...|........:.:|
Mosquito    74 NAPHIFAIADAAYRVLKQRNNDTCIMISGESGAGKTEASKIIMKYIAAVTNQGKQGEIERVKNVL 138

  Fly   283 -EAAPLLEAFGNARTARNDNSSRFGKYLEVYFK-SGAIVGAKITQYLLEKSRIVTQAPGERNYHV 345
             ::..:||.||||:|.|||||||||||:::.|. .|..||..||.|||||||::.|..||||:|.
Mosquito   139 IKSNAILECFGNAKTNRNDNSSRFGKYMDIEFDYKGDPVGGIITNYLLEKSRVIQQQSGERNFHC 203

  Fly   346 FYELLGGLSETERSKYGLL-EADKYFYLNQGATDCASGRVDWESLQGAMQVLGVSEGEREGIVRV 409
            ||:||.|.:..|..:|.|: :...|.|.|||:|:..|.:.|:.:..|.:|.||.|..|...:.|.
Mosquito   204 FYQLLRGGANNELQQYNLVRDPAAYHYTNQGSTEILSEKSDYRATTGGLQALGFSAEEISMVWRT 268

  Fly   410 LAAVLHLGNVYFHRRQLRHGQEGVEVGSDAEIKWAAHLLHISADGLHRALTSRTTEARAERLHTP 474
            :||:|||||:.|..:     .|.:.:.:...:...|.||.::|:.:..|||.|...||.|.:...
Mosquito   269 VAAILHLGNIEFKMK-----DEKITIANGKTLANVAQLLQVTAEEMRAALTERVIAARGEIMTKS 328

  Fly   475 LGIDQALDARDAFAKALYAGLFNWLVSRINSIVQKGGTHDAHR----ISILDIFGFEDLAENSFE 535
            ....||...|||.|||:|..:|.|::.|||..:...|:....|    |.:|||:|||....||||
Mosquito   329 HDTKQAEYGRDALAKAIYDRMFTWIIQRINKAIVVPGSTTQKRYNKVIGVLDIYGFEIFDRNSFE 393

  Fly   536 QLCINYANENLQLYFNKHVFKLEQAEYARERLEWTPLAWDDNLPVIHLLAKKPVGICHLLDDES- 599
            |.||||.||.||..|.:.|.|.||.||.||.:|||.:.:.:|..:..|:.:...|:..::::..
Mosquito   394 QFCINYCNEKLQQLFIELVLKQEQEEYNREGIEWTNIEYFNNQIICALVEQADKGVIAIMNEACL 458

  Fly   600 NFPRATD---LSFLEK--CHYNHALS--------ELYARPRIGAQEFGVTHYAGQVWYCVDGFLD 651
            |..:.||   |..::|  .|:.|..|        ||..:     ::|.:|||||.|.|.:.||::
Mosquito   459 NVGKITDEMLLGDMDKKLSHHPHYSSRQLKPMDKELRHK-----EDFRITHYAGDVIYSISGFIE 518

  Fly   652 KNRDALRGDVLELLASSRLPLVGELTKQLRAQRDAGKTLPKGSNGRFVTMKPRTPTVAARFADSL 716
            ||||.|..|...||..|...::..:..:  ..:|..||          |.:|.  |....|..|:
Mosquito   519 KNRDTLFQDFKRLLYGSHDKVISSMWPE--GAQDIAKT----------TKRPL--TAGTLFQKSM 569

  Fly   717 QQLLQSMGRCHPWFVRCIKPNQEKHALRMDMPCVLQQLRYLGMLDTIQIRQRGYPVRLRFQHFVE 781
            .:|:.::.|..|.:|||:|||..|.....|...|..|:||||:|:.:::|:.|:..|.|:..|:.
Mosquito   570 AELVATLLRKEPLYVRCVKPNDIKSPTVFDDVRVEHQVRYLGLLENVRVRRAGFVHRQRYDKFLL 634

  Fly   782 RYRHL--LPSPLARGTPYRELCRALLEAMPRTGVEGPDYQLGATRVFLR--EALHRALESGRTER 842
            ||:.:  ...|..||...|:..:.|:....    .|.|.:.|.|::|:|  :.|. |||..|.:.
Mosquito   635 RYKMISQYTWPNFRGGNDRDGVKVLMNEKN----FGHDVRFGKTKIFIRSPQTLF-ALEQQRNDM 694

  Fly   843 LRRAAVSVQRHVRGMLVRRQLARRQAA---------------ATRLQARWRGQRAQQRYERLRKG 892
            :......:|:.|||.:.|::..:.:||               ...|..|:|..|..:.|   .||
Mosquito   695 IPHIVTLLQKQVRGWIARQKYKKMKAALVIMRHYRKYKLKSYVQDLAVRFRNARTLRDY---GKG 756

  Fly   893 ALTAQRLWRGRQARRRVQQLRSDHRR----RQEAREAAQRAREAREAKQAVLERSQL-------- 945
            ....|....||||.|:::.|.|..|.    |:..||...:.|....|..|..:|.:.
Mosquito   757 IQWPQPPLVGRQAERQLRMLYSRWRAAMILRKYPREEWPQLRLQIIAASAFRKRRKCWGHDRRWL 821

  Fly   946 -SYLDIPAE-------------------------LAFI--YSKLQGWSPPHGDRHLVKVLGTV-- 980
             :||.|.||                         .||:  ::|..    ...||.::...||:
Mosquito   822 GNYLSIVAENSNYSSYNASVRNIKNVDNFDTIVFSAFVKKFNKCN----KSADRAIIVTDGTIYK 882

  Fly   981 -PGPPSSAVQLPEDLGQFSFGKFSSVYCNGLRLQPRREPITAPLLTRAASRDQDFQDALAVFKLI 1044
             .||.:               ||.    |..|....|| ||:  ::.:..|||     ||||.
Mosquito   883 LDGPKN---------------KFR----NMKRTVAIRE-ITS--ISVSPGRDQ-----LAVFH-- 918

  Fly  1045 LRWSND--KALEG----AKEKLLADYIVH 1067
            ...:||  .:|:|    .||..:.:.:.|
Mosquito   919 SHHNNDLIVSLQGEHQPLKEDRIGELVAH 947

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo10A	NP_001036269.2	MYSc_Myo15	169..828	CDD:276838	249/684 (36%)
		PTZ00121	<828..>943	CDD:173412	35/135 (26%)
		MyTH4	1014..1171	CDD:470587	18/60 (30%)
		Ubl1_cv_Nsp3_N-like	1178..>1245	CDD:475130
		MyTH4	2704..2810	CDD:459939
		FERM_B-lobe	2920..3025	CDD:271216
		FERM_C_MyoXV	3029..3138	CDD:270022
Myo31DF	XP_061516868.1	None