|
Fly 159 DMTLLDDLHEASLLWNLRLRYDKGLIYTFAGSILIAVNPYKMFPDAYGLEVAKQYAGRPLGS-LP 222
|:..|.||:||:||.|||.|::.|.|||:.|||||||||:|..| .|..:..:.|..:.:|. ||
Mosquito 170 DLCQLPDLNEATLLENLRQRFEAGHIYTYVGSILIAVNPFKFHP-IYNPKYVRLYQNQRIGPILP 233
Fly 223 PHLFAIGAAAHAAL---PSPQVVVISGESGSGKTESTKLVMQYLAAVVPGGGSASAVITEQILEA 284
||:|||...|:..: ...|.:||||||||||||||..::.:|.|:...|...|.| .:.||.|
Mosquito 234 PHIFAIADNAYYNMLKEKRNQCIVISGESGSGKTESTNFLLHHLTALSQKGAHGSGV-EQTILSA 297
Fly 285 APLLEAFGNARTARNDNSSRFGKYLEV-YFKSGAIVGAKITQYLLEKSRIVTQAPGERNYHVFYE 348
.|:|||||||:||.|:|||||||:::| |.::|.:.||.:.:|||||||||:|...||||||||.
Mosquito 298 GPVLEAFGNAKTAHNNNSSRFGKFIQVNYRENGMVQGAVVQKYLLEKSRIVSQGHYERNYHVFYY 362
Fly 349 LLGGLSETERSKYGLLEADKYFYLNQG--ATDCASGRVDWESLQGAMQVLGVSEGEREGIVRVLA 411
||.|.::.||....||.|:||.|||.. ..:....:.::..|:.:|:::|.|..::..:..||:
Mosquito 363 LLSGATDAERDALHLLPAEKYHYLNAKNLTLENCDEKYEFSRLKQSMEMVGFSAEKQRRLFNVLS 427
Fly 412 AVLHLGNV-YFHRRQLRHGQEGVEVGSDAEIKWAAHLLHISADGLHRALTSRTTEARAERLHTPL 475
|||.|||| :|.::...|..|.|:|.:...:...:.||.:..:.|..||||:..:|..|.|....
Mosquito 428 AVLLLGNVEFFPKKSTYHHDESVQVRNPDVVGLISELLRVKQETLMSALTSKRVKASGETLIMQY 492
Fly 476 GIDQALDARDAFAKALYAGLFNWLVSRIN-SIVQKGGT-HDAHRISILDIFGFEDLA-ENSFEQL 537
.:.:|:.||||.||.||..||:|:|.::| :::.|... |..|.|.:||||||||.. :||||||
Mosquito 493 KLPEAIAARDALAKCLYGALFDWIVLQVNHALLNKDQVLHTGHSIGVLDIFGFEDFGPQNSFEQL 557
Fly 538 CINYANENLQLYFNKHVFKLEQAEYARERLEWTPLAWDDNLPVIHLLAKKPVGICHLLDDESNFP 602
|||||||:||.|||.||||.||.||.||.::||.:.:.||...:.|...||.|:..:|||..|||
Mosquito 558 CINYANEHLQYYFNLHVFKYEQKEYKREGIKWTDIEFLDNYGCLQLFESKPSGLLCILDDLCNFP 622
Fly 603 RATDLSFLEKCHYNHALSELYARPRIGAQEFGVTHYAGQVWYCVDGFLDKNRDALRGDVLELLAS 667
.||:.:.|:|.:..|..:..|.:|:.....|.:.||||:|.|.|....:||.|.:|.|::.:|.:
Mosquito 623 GATNETLLQKFNSVHKDNAFYEKPQRKENAFIIKHYAGKVKYQVAEMREKNLDLMRQDIVSVLKN 687
Fly 668 SRLPLVGEL-------------------------------------------------------- 676
|.:..|.||
Mosquito 688 SSMAFVRELVGADPVAVFRWAILRAFFRGYFAFRSAGIKHRKERADMSYNKLATKTRYRAPNDSI 752
Fly 677 ----------------------------------------TKQLRA---QRDAGKTLPK------ 692
||...| ||:..|..||
Mosquito 753 VSHLVTVSSVNLTINRIAKLFCARRPVRDAGMLDRYRNYSTKSATAKGGQRERRKNWPKRISNAM 817
Fly 693 ----------------------------------------------------------------- 692
Mosquito 818 SDITSGHSNNQACSPNSNLAYHRQSLGNAGYGAAGAASPGATGGTPRRSWSSFAFNNKNFPDGKL 882
Fly 693 ------------------------------GSNG------------------------------- 696
||.|
Mosquito 883 NYECNQQQDQTPQYHSKHLQSTAASSSSIYGSGGGGKSSANANSSASGAPNSGGVTGTGSGKGYG 947
Fly 697 --------RF-------------VTMK-----PRTP----------------------------- 706
|| :.|| ||..
Mosquito 948 LGSAAARNRFERSGQDVMARASQIVMKNKSFRPRERPKKGLKNLQSVKTLSAGQNLSNQTSAIKT 1012
Fly 707 -----TVAARFADSLQQLLQSMGRCHPWFVRCIKPNQEKHALRMDMPCVLQQLRYLGMLDTIQIR 766
||.|:|.:||..|::::.:.:|:|:||||.|..|...:.|...|.:||||.|||:|::||
Mosquito 1013 RKQPLTVTAQFQNSLIALMETLNQANPFFIRCIKSNPNKIPNQFDDATVTRQLRYTGMLETVRIR 1077
Fly 767 QRGYPVRLRFQHFVERYRHLLPSPLARGTPYRELCRALLEAMPRTGVEGPDYQLGATRVFLREAL 831
:.||.|||.::.|::.||.|||..|.... :.:.:.|....:....||||.|::::||:.
Mosquito 1078 RAGYNVRLTYEEFIQLYRILLPKGLVSSQ------KDVRDFMSTMDLNKQHYQLGLTKIYMRESQ 1136
Fly 832 HRALESGRTERLRRAAVSVQRHVRGMLVRRQLAR---------------------------RQAA 869
...|:.....::..:.:.:||..|.:|.|::..: |..|
Mosquito 1137 KMRLDISLHTKIIDSIICIQRWFRAILQRKKYCQYRNAACTIQSYWRDYLREKQEKFTRKIRNHA 1201
Fly 870 ATRLQARWRGQRAQQRYERLRKGALTAQRLWRGRQARRRVQQLRSDHRRRQEAREAAQRAREARE 934
||.:||.|||...::.|.:|:.|.|..|...||.|||.|.::|.|...:|:.|:
Mosquito 1202 ATVIQATWRGYTVRKWYSKLKTGVLIIQARIRGNQARSRFKELLSKKLQRERAK----------- 1255
Fly 935 AKQAVLERSQLSYLDIPAELAFIYSKLQGWSPPHGDRHLVKVLGTVPGPPSSAVQLPEDLGQFSF 999
|..:| .:|.| :.:||.....|... |....
Mosquito 1256 -----LRSTQ----SLPVE---------------------RPIGTTAAGGSYGG------GGGGA 1284
Fly 1000 GKFSSVYCNGLR-LQPRREPITAPLLTRAASRDQDFQDALAVFKLILRWSNDKALEGAKEKLLAD 1063
|...|.|...:. ::.|::|| |.:.|: |:.|:.:. :.::|| .|.:.:.||
Mosquito 1285 GGGGSTYPEIVHAIEHRKKPI--PAVGRS------FETAIDIV------NKNRAL-FADDSMSAD 1334
Fly 1064 YIVHKALSSRGLRDEILVQLCNQVHGLPPNSGEATRLWQLLGQCLCCFQPSAAFSKYLMRFVDDE 1128
|:||:
Mosquito 1335 ------------------------------------------------------------FIDDD 1339
Fly 1129 APESLRPLLLRQLLRQQGGGTSSGAVGAGACRSFVPAWLEWRAWTRGCDMALPLTLPDEASQTVA 1193
..| .:...::..|:....:.| |..:|...
Mosquito 1340 EDE-------EEEEEEETTGSRQATITA--------------------------TCGEEEED--- 1368
Fly 1194 VDSWTSCEEAAALAVSSLGVASRGWTLVLDDGQQLTDSCGLDYVMDLIAEKELCPAFPAPRSDLL 1258
||........|| ::||.|.:.::
Mosquito 1369 -------EEDDEEGYEDLG--------LVDDPQYMANN--------------------------- 1391
Fly 1259 RSGAKFARTTLPDAVKRPAVPPPAPPTSSGKEDVPRERRSSRELLSRSSALNERYFEREPSPGPG 1323
|:.|...||..|....:|..:|. ||.| ||:|.:.....|.|
Mosquito 1392 -------RSALMHPVKTAAPVTTSPTVNSA-------------LLDR----NEKYIKSLVISGGG 1432
Fly 1324 QGSST--------GQAKSRSKSLDDLLAGDIVPVPTDCDSQE-----PLHTLGL---SESRLND- 1371
.|.:| |.....:.|:...::|.....| ...|| ||....: |:|..:|
Mosquito 1433 GGGATASSSPSAGGGGGGNASSVGSSVSGAYQKAP--LQRQEDVLDRPLRMYDIERASKSTFDDT 1495
Fly 1372 -----RYH-----SAERLAPVGK-DTGPRYQKSQHAGRRSHAASHGS-------HSSKYADKAEY 1418
||. |:....||.: |:|| |..|| |...|.|| ...:|.|.|.|
Mosquito 1496 ELAKYRYERGGGVSSTVKLPVRRVDSGP----SSVAG--SGTGSGGSTMGRPGIQRFRYGDTASY 1554
Fly 1419 ATRSSAMSDTSEAPSLASHVRRVRVPSQASDVDQFLDDLFSPVLDGSLDELSDARSLAASIRGGS 1483
. || ..||..:
Mosquito 1555 G--------------------------------------------GS-----------GMIRNQN 1564
Fly 1484 YEQENEAESEIDDLDDYINDIFQPIPLVQNLEKLTSKDQLAAIIKGGGVASKPEERDEESEIEDL 1548
:...:.:.|.::.: ::| |..|.:.|....||..|
Mosquito 1565 HSNNSYSNSNVEIV--FVN---------------TGLDSVGAPAGSGGTGS-------------- 1598
Fly 1549 DDYINELFEPIPVAEGLDK-------LTSKE---HLAVSIRGGGSTDSNGADPLLHQL-MQLPG- 1601
....|.|..|:: ||..: .||.|:| .||. ||.|.| .:.||
Mosquito 1599 -------LSSSPAARNLNRNSISSGTLTQTQVPPSLASSMR----RDSL---PLSHHLGTRTPGD 1649
Fly 1602 ETESGPALYQQQVQRAFLQSAMAQNLQIQQQLLAQNQALQTLLSQQAAAAAANNSTSPPPAPPIL 1666
|..|...::|||.| ..|....|..|.|||...|:|..|..||..:::.|:::..|...:|
Mosquito 1650 EINSNYHMHQQQQQ--LQQQHQQQQQQQQQQQQQQHQHQQQPLSPSSSSVASHHQQSQTGSP--- 1709
Fly 1667 SSLSISPPPPQSPMRMKATRSSLVVMESLQPPPPPPPPPMPPPLECKDPSETRHFLDPYGRAKTV 1731
:|.|| :|| || .|.|.
Mosquito 1710 --MSHSP-------------------QSL-------------PL--------------VGSAG-- 1724
Fly 1732 RIGKW---RWPPPQDEPQFQTEEDFFAFKMRQHQRKTTPQAQHHQMTSNGG-MMESGP------- 1785
.||.: ::||..: :....|..:.:....:.|..|.|. |:.|.|
Mosquito 1725 HIGNYQNLQFPPTSN------------YHQHHHHHQQSVYNNNAQPVSTGAKMVTSTPYGAAGSN 1777
Fly 1786 --GARGASATAIEWEEFEIESPTPPPMSGQLMRSSIRLETTTTTT---------------TSAVN 1833
.|.||||:| ....:.:..|...:.... |||||| .|||.
Mosquito 1778 SSYATGASASA---SSQRVSAAYPDDFAQNYY-------TTTTTTPKGKAAALLGTAKSEDSAVT 1832
Fly 1834 NRDRDRETQDVGQPMQSVVTTKLAKKSFEIGADRPPPGSVGKLKLSSEMRQRLEQVTAGHSVRST 1898
| ..:||....:....||| || ||:| .::||: :|.
Mosquito 1833 N-------AGLGQSKYPLDRATLAK------AD------------SSDM-----VLSAGN--KSA 1865
Fly 1899 VSTKSEQRAPAKLEDTRKLMLQQQLGGLFASVSGGNS---GPGGVVDSHATVRTQIERMEGKLSP 1960
::..:...:..:::.|. :.::||.| |.|:| .||..:.....|.|......|..|
Mosquito 1866 INQGAGNASGRRIKSTN--LSEEQLVG-----SSGSSVSYHPGTGLTRRGPVGTSASGGSGNTS- 1922
Fly 1961 PPAPPSGGWPGVLLPPAPSVPAPPPPIRPPSMAPPAPPPAPQSPPTARSPEPEPD-----YRTSS 2020
|.|..|..| ....|.||.:.|..|.: |::|:
Mosquito 1923 -----STGVAGDTL------------------------KRRNSDPTNKIPLLEVNRGNDMYQSST 1958
Fly 2021 SQVVKEHVPAFIQR----------QERDTF---GAVRQQQMISSHHLHLEDHSASSSPAVAAWEQ 2072
...:..|....:|| ||.|:| |.......:..|...:::....|.....| ::
Mosquito 1959 RINIAGHQFRKVQRINKAERCACCQEIDSFVNEGYRCLDCKVLVHTKCIQNGGIKSLQCAVA-KR 2022
Fly 2073 AERERSRSRSRSRDREDYSESVWDRAEVEGPASGSGSE------------------KERE----- 2114
::|.|:............|.|..|:....|..|.||.: ||.:
Mosquito 2023 SKRIRTGGAGGGSGGLGGSSSKHDKHHPIGGGSASGQKISSTREYTDSTDKIISDAKELQLMQDF 2087
Fly 2115 ------KRERERERLYEI----RQVERERESHKVYQPAPP------------RVIQAS----MDT 2153
|.|.:.|:..|: :|..||.:.:.|.|.:.. |.:.|: ::|
Mosquito 2088 ITQKICKMESDCEKPSEVDRVFKQALREFKDNLVAQYSVAHRQNSDVLNIKYRDLIANFEQVIET 2152
Fly 2154 TGGHRRE-DRTGGLATFRTHMAQ------------KYEHERKRK---SSASSGMREELDSMHMTT 2202
|.|.:.: ..|.|:..||..|.: |.:.::||| .:..:|...:|..:::.|
Mosquito 2153 TSGRKNDFPLTMGVNAFRGFMNEFMNSRETEKPKTKRKKDKKRKHDDHTTFNGHTFQLTILNIAT 2217
Fly 2203 PPPVIVPAPVPP---------------------PSSTSPGLGVVSGVLMGSGSGGST----ACLT 2242
...:.....:.| .:|.:.........|:|:|..||. .|
Mosquito 2218 ACEICQQFLLWPIERGLVCQNCKLTCHKKCYQKSASCNKIANADPNSLLGAGGSGSAVVAGGC-- 2280
Fly 2243 YNRVPWKLRVRKEVFQPHEPIGPPVALDLLFAQVLGDVFGVTPCLRI---------TPQEKSSAL 2298
.|.|.| |....:...:||| |...: .|.:.:..:
Mosquito 2281 ------------------GPDGQP----LYGGGIPTKLFGV-PLTALCGNSSDGVKIPAQINKLI 2322
Fly 2299 NMLHGHGVSVDTLSNRNG-----------------SGAGGGG----NGGQVRALVKRHLVDMARD 2342
.|:..||:..:.:..::| |..|||| ....|..|. ..|....|:
Mosquito 2323 MMIEMHGLYSEGIYRKSGVSSKIKDLKAKMDRAVTSADGGGGEMDFESYNVHVLT-NVLKSFLRE 2386
Fly 2343 WP---LYFARLFAVQGAPLYPD--------------------VSIMGVSHSGLYLARRDADYLIV 2384
.| |.|.| |.| |..:..:|..|: .|...:|.:
Mosquito 2387 MPEPLLTFDR---------YDDFLRAADLSDGSDRVQTLLSLVKKIPPAHHCLF--ERLIFHLAL 2440
Fly 2385 VQAISFGEIQSAVTLP---RPAALQLNLRNGKHLALH--AARAAAIQSMVTTFVQEFRKSQSKAS 2444
|..:......||.:|. .|..|:.|.......:|: ..:...:::::|..:...:.:.:...
Mosquito 2441 VAKLEQYNRMSASSLAIVFAPCVLRTNRYVPAQDSLNDIGRQTKCMETLITQKMLNVKSTLADID 2505
Fly 2445 TLSSGARAAAQTLNVPLERLESRQAHAQ------RNEHGVDGGSRQNEQLQQSELHHHLQQQQQQ 2503
||.: ||.|....|..|.|.:...| |...|:..|.....:.::..|..|:|:.:::
Mosquito 2506 TLDT----AAHTATARLSTLRSSKVFTQEEMANARGGSGIAVGGLLETETEEMLLEGHIQEIRKE 2566
Fly 2504 Q 2504
:
Mosquito 2567 K 2567
| 
