DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2145 and endou

DIOPT Version :9

Sequence 1:	NP_001285102.1	Gene:	CG2145 / 32027	FlyBaseID:	FBgn0030251	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	NP_001074167.1	Gene:	endou / 791216	ZFINID:	ZDB-GENE-070112-2012	Length:	303	Species:	Danio rerio

Alignment Length:	290	Identity:	106/290 - (36%)
Similarity:	153/290 - (52%)	Gaps:	14/290 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   314 TTVRPG-FQSSGNSVA--TDDEIRQLTELLYTKESN-SQIGNIQVNLQGRTRSIDSA---DEAPN 371
            |.:..| |.|...|:|  :|.||:.|:|.||..:|| :....:.::.|....|..:.   |.:|.
Zfish    12 TLISQGHFDSLDLSLANVSDAEIKSLSETLYKLDSNRATASELLIDPQTLIPSSQTGSGNDLSPQ 76

  Fly   372 PLL-TVDSKALESPTIVKMRLLFNNYEHDTHVNEHVTPNERKEENDFLDAVMATPVMRQAMLFLQ 435
            ||. .|.|..|..||......|.:||:..|...|.|..:|.:|::.||...|.|.:.::...||.
Zfish    77 PLFKVVSSTLLSKPTYEAFLDLLDNYKKMTGEVEDVPSHEEQEQDSFLQQTMNTNLGKELFNFLH 141

  Fly   436 QKGVVSPDPKTHRDLVKELWFTQYSRGQG-KIGSSGFEHVFVYEVKDGTIIGFHNWVYIGDEEKD 499
            .|||.....:..:|| |.:||..|||..| |:.||||||:||.|:|.|.:.|||:||.....||.
Zfish   142 SKGVYGSQSEFLQDL-KMMWFGLYSRSDGVKLDSSGFEHIFVGEIKGGKVSGFHSWVQFYQCEKQ 205

  Fly   500 GRFDYKGYMKEQDIGTKGKIVKIRFSHQGLNKPVNTVFVGTSPELELALYTVCFQLRPDRTCPVS 564
            |..:|..:..:....|...::.::|:..|..|.:.:.|:|.|||.:||:|::|:..||.:.|.||
Zfish   206 GILNYYSHSFDGPWTTYPDVLGMQFNWDGYFKELGSAFIGCSPEFDLAIYSLCYITRPGKKCDVS 270

  Fly   565 LGNSKFGIVTYSWRYR----GKNLIGSAYP 590
            ||....||.||:|...    ||..||||||
Zfish   271 LGGHSLGIQTYTWDKSSYGDGKKFIGSAYP 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2145	NP_001285102.1	XendoU	330..590	CDD:286496	98/269 (36%)
endou	NP_001074167.1	XendoU	31..300	CDD:286496	98/269 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594072
Domainoid	1	1.000	160	1.000	Domainoid score	I4038
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H48394
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D596408at33208
OrthoFinder	1	1.000	-	-		FOG0003014
OrthoInspector	1	1.000	-	-		mtm6587
orthoMCL	1	0.900	-	-		OOG6_102937
Panther	1	1.100	-	-	LDO	PTHR12439
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2515
SonicParanoid	1	1.000	-	-		X4814
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.840