DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2145 and Endou

DIOPT Version :9

Sequence 1:	NP_001285102.1	Gene:	CG2145 / 32027	FlyBaseID:	FBgn0030251	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	NP_001177998.1	Gene:	Endou / 680317	RGDID:	1593011	Length:	411	Species:	Rattus norvegicus

Alignment Length:	303	Identity:	103/303 - (33%)
Similarity:	155/303 - (51%)	Gaps:	26/303 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   296 GSSVGPHKDGGGGGGGGTTTVRPGFQSSGNSVATDDEIRQLTELLYTKESN-SQIGNIQVNLQGR 359
            |:..|.|:               ||..|.::: |.:|::.::|.:|..:.| :|..:|.:|.|.:
  Rat   120 GNLCGDHE---------------GFSHSSDAI-TKEELKSISETIYRVDINKAQKKDIVLNSQNQ 168

  Fly   360 TRSIDS---ADEAPNPLLT-VDSKALESPTIVKMRLLFNNYEHDTHVNEHVTPNERKEENDFLDA 420
            ....::   .|..|.||.. |:.|....||......|.|||:..|...||.:..:.:|:..||..
  Rat   169 ISPAETGNQVDRCPEPLFKYVNEKLFSKPTYAAFINLLNNYQRATGHGEHFSAQQLEEQVVFLRE 233

  Fly   421 VMATPVMRQAMLFLQQKGVVSPDPKTHRDLVKELWFTQYSRGQGKIGSSGFEHVFVYEVKDGTII 485
            ||.|.||::...||:.:.......:...|| |.:||..||||..:..||||||||..|||.|.:.
  Rat   234 VMKTAVMKELYSFLRHQNRYGSQQEFVEDL-KNMWFGLYSRGNEEGDSSGFEHVFSGEVKKGKVT 297

  Fly   486 GFHNWVYIGDEEKDGRFDYKGYMKEQDIGTKGKIVKIRFSHQGLNKPVNTVFVGTSPELELALYT 550
            |||||:....:||:|..||..:..:....:...::.::|:..|..|.|.:||:|:|||.|.|||:
  Rat   298 GFHNWIRFYLQEKEGLLDYYSHNYDGPWDSYPDVLAMQFNWDGYYKEVGSVFIGSSPEFEFALYS 362

  Fly   551 VCFQLRPDRTCPVSLGNSKFGIVTYSW---RY-RGKNLIGSAY 589
            :||..||.:.|.:|||.....|.||:|   .| .||..|.:||
  Rat   363 LCFITRPGKKCHLSLGGYPLAIQTYTWDKTTYGNGKKYIATAY 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2145	NP_001285102.1	XendoU	330..590	CDD:286496	96/269 (36%)
Endou	NP_001177998.1	Somatomedin_B	22..60	CDD:279385
		Somatomedin_B	88..125	CDD:279385	1/4 (25%)
		XendoU	139..405	CDD:286496	94/266 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352173
Domainoid	1	1.000	161	1.000	Domainoid score	I3916
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H48394
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D596408at33208
OrthoFinder	1	1.000	-	-		FOG0003014
OrthoInspector	1	1.000	-	-		otm45493
orthoMCL	1	0.900	-	-		OOG6_102937
Panther	1	1.100	-	-	LDO	PTHR12439
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4814
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.850