DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2145 and Pou3f3

DIOPT Version :9

Sequence 1:	NP_001285102.1	Gene:	CG2145 / 32027	FlyBaseID:	FBgn0030251	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	NP_032926.2	Gene:	Pou3f3 / 18993	MGIID:	102564	Length:	497	Species:	Mus musculus

Alignment Length:	478	Identity:	92/478 - (19%)
Similarity:	143/478 - (29%)	Gaps:	143/478 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 PKSVVVTPTAANKPPPLV--------------------ISHAPLMPLGPRPDTPGSSPFGASQNP 120
            |.|..||..|....|..|                    :|||... :...|....::...|:...
Mouse    52 PGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAASNGGHMLSHAHQW-VTALPHAAAAAAAAAAAAV 115

  Fly   121 QTPPQWPSSTRATPSHPSQPSQPSQQPPLPGFASYRPQKPQ----PNSYDLSYGG---------- 171
            :....|..|.......|.||.||   ||.|      ||.|.    ....||..|.
Mouse   116 EASSPWSGSAVGMAGSPQQPPQP---PPPP------PQGPDVKGGAGREDLHAGTALHHRGPPHL 171

  Fly   172 GPQPAPAGTGRPGFGLGISSTTSTTTTAKPITSTTGKTPQQKEDFPALPGPRRP-------SQKE 229
            ||.|.|...|.|| |.|.::..:....|....:          ..|::.|.::|       ||..
Mouse   172 GPPPPPPHQGHPG-GWGAAAAAAAAAAAAAAAA----------HLPSMAGGQQPPPQSLLYSQPG 225

  Fly   230 DFPALPAPKTPPGSPTPTPGSPSAWQSPL-------PTPQ---------HPVHPPTKATSAATPT 278
            .|........|||......|:....||.:       .||:         |..||.
Mouse   226 GFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPH---------- 280

  Fly   279 PTPTPSFSSSVTPTPAHGSSVGPHKDGGGGGGGGTTTVRPGFQSSGNSVATDDEIRQLTELLYTK 343
                       .|.|.|..  ||...||||.|.|..:..|   .|.....|.|::.|..:..  |
Mouse   281 -----------PPHPHHAQ--GPPHHGGGGAGPGLNSHDP---HSDEDTPTSDDLEQFAKQF--K 327

  Fly   344 ESNSQIGNIQVNLQGRTRSIDSADEAPNPLLTVDSKALESPTIVKMRLLFNNY--EHDTHVN--- 403
            :...::|..|.::.....::.....:...:...::..|....:.|::.|.|.:  |.|:...
Mouse   328 QRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPT 392

  Fly   404 --EHVTPNERKEENDFLDAVMATPVMRQAMLFLQQKGVVS------PDPKTHR--------DLVK 452
              :.:....||.:             ::..:.:..||.:.      |.|....        .|.|
Mouse   393 SIDKIAAQGRKRK-------------KRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLEK 444

  Fly   453 E---LWFTQYSRGQGKIGSSGFE 472
            |   :||....:.:.::...|.:
Mouse   445 EVVRVWFCNRRQKEKRMTPPGIQ 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2145	NP_001285102.1	XendoU	330..590	CDD:286496	23/167 (14%)
Pou3f3	NP_032926.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	32..62		4/9 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	121..189		25/77 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	230..316		24/111 (22%)
		POU	311..385	CDD:197673	11/75 (15%)
		Homeobox	406..460	CDD:395001	9/53 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	458..497		1/10 (10%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000