Protein Alignment v and tdo2a

DIOPT Version :10

• Sequence 1: NP_511113.1
• Gene: v / 32026
• FlyBaseID: FBgn0003965
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_001096086.1
• Gene: tdo2a / 100008541
• ZFINID: ZDB-GENE-030131-1187
• Length: 406
• Species: Danio rerio
• Alignment Length: 380
• Identity: 205/380 - (53%)
• Similarity: 275/380 - (72%)
• Gaps: 17/380 - (4%)

  Fly     3 CPY-------------AGNGNDHDDSAVPLTTEVGKIYGEYLMLDKLLDAQCMLSEEDKRPVHDE 54
            |||             ....||...:.:...::.|.|||:||.|||::.:|.:.||.....:|||
Zfish     4 CPYFQRKFLSTSKQHLKEEENDEAQTGINKASKGGLIYGDYLQLDKIVTSQVLQSELKGNKIHDE 68

  Fly    55 HLFIITHQAYELWFKQIIFEFDSIRDM-LDAEVIDETKTLEIVKRLNRVVLILKLLVDQVPILET 118
            ||||:|||||||||||:::|.||:|:: :...|.||...|::..|::|:|:|.:||:||..:|||
Zfish    69 HLFIVTHQAYELWFKQVLWELDSVREIFISGHVRDERNMLKVNTRIHRIVMIFRLLLDQFAVLET 133

  Fly   119 MTPLDFMDFRKYLAPASGFQSLQFRLIENKLGVLTEQRVRYNQK-YSDVFSDEEARNSIRNSEKD 182
            ||.|||.|||.||:||||||||||||:|||:||...|||.||:: |.|.|.|:|: ..:.:||::
Zfish   134 MTALDFYDFRGYLSPASGFQSLQFRLLENKIGVPHNQRVPYNRRHYRDNFRDQES-ELLLHSEQE 197

  Fly   183 PSLLELVQRWLERTPGLEESGFNFWAKFQESVDRFLEAQVQSAMEEPVEKAKNYRLMDIEKRREV 247
            |:||:||::||||||||||.|||||.|.::::...|..:.:...::|..:.|...|.::.|:|::
Zfish   198 PTLLQLVEQWLERTPGLEEDGFNFWGKLEKNIFEGLRREKEHIEQKPASERKEEMLAELIKQRDI 262

  Fly   248 YRSIFDPAVHDALVRRGDRRFSHRALQGAIMITFYRDEPRFSQPHQLLTLLMDIDSLITKWRYNH 312
            :.|:||...||.||..|.||.|::|||||:||.|||:||||..|.||||.|||||:|:|||||||
Zfish   263 FLSLFDEKRHDHLVSTGQRRLSYKALQGALMIYFYREEPRFQVPFQLLTSLMDIDTLMTKWRYNH 327

  Fly   313 VIMVQRMIGSQQLGTGGSSGYQYLRSTLSDRYKVFLDLFNLSTFLIPREAIPPLD 367
            |.||.||||.:. ||||||||||||||:|||||||:|||||:||||||:.:|.||
Zfish   328 VCMVHRMIGRKD-GTGGSSGYQYLRSTVSDRYKVFVDLFNLATFLIPRDWVPKLD 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
v	NP_511113.1	Trp_dioxygenase	11..357	CDD:281317	193/347 (56%)
tdo2a	NP_001096086.1	Trp_dioxygenase	25..371	CDD:281317	193/347 (56%)