DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43901 and LRG1

DIOPT Version :9

Sequence 1:	NP_001096948.2	Gene:	CG43901 / 32024	FlyBaseID:	FBgn0264502	Length:	2281	Species:	Drosophila melanogaster
Sequence 2:	NP_010041.2	Gene:	LRG1 / 851358	SGDID:	S000002399	Length:	1017	Species:	Saccharomyces cerevisiae

Alignment Length:	336	Identity:	71/336 - (21%)
Similarity:	130/336 - (38%)	Gaps:	58/336 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  1349 STSASVSATEQQQFEAQKPPPIPPKET---SPTQISGILKGGKLWKQDSISQQQSDDQNNTTSED 1410
            |...||..|..:| :|:|...:...||   .||: .|..|...:...|..|.||...:.|..|..
Yeast   545 SRRESVRVTHNKQ-QARKSVILETAETDLNDPTK-QGDSKNLVIQTDDPSSSQQVSTRENVFSNT 607

  Fly  1411 ESGGTKRSVRFVTEDQANAGTDSDAQSLAGDLDDSENQINELIPIKK---HSTLFNNALRPNSAV 1472
            ::.......|.|..:||.. ...:|.:....|.:::::.:.::|.|.   :|.|....|   |.:
Yeast   608 KTLTLDDISRIVAAEQARE-LRPNAFAHFKKLKETDDETSNVVPKKSGVYYSELSTMEL---SMI 668

  Fly  1473 RQLFPSVSAHQA------PVLTSEALRAFDESKRAGCLVTHLPGSCGDSDTLRRSME-RNILRRS 1530
            |.:..|:.|.:.      |..||.....|...|:       :.||..:...:..||| :..:.::
Yeast   669 RAISLSLLAGKQLISKTDPNYTSLVSMVFSNEKQ-------VTGSFWNRMKIMMSMEPKKPITKT 726

  Fly  1531 --------LIKKKAVKSDISLEERIKQLTCDIDEDLAEELQRAVDEDAESVAERADELAQ-RNSP 1586
                    |.:|..|.||:.:.....::...||| |...| |.:|...|.:..:...:.: |...
Yeast   727 VFGAPLDVLCEKWGVDSDLGVGPVKIRIPIIIDE-LISSL-RQMDMSVEGIFRKNGNIRRLRELT 789

  Fly  1587 AG-EENPNPVPGSGQAHKFVNGEKSFSPSSSVSSSSSGSSAYKKI------ADIFNRDKKQEKI- 1643
            |. :.||...|             .||..:::..|:......:::      .|::....|..||
Yeast   790 ANIDSNPTEAP-------------DFSKENAIQLSALLKKFIRELPQPILSTDLYELWIKAAKID 841

  Fly  1644 MEMEENPIVII 1654
            :|.|:..::::
Yeast   842 LEDEKQRVILL 852

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43901	NP_001096948.2	None
LRG1	NP_010041.2	LIM1_Lrg1p_like	28..90	CDD:188777
		LIM	98..149	CDD:259829
		LIM3_Lrg1p_like	419..475	CDD:188779
		RhoGAP_fLRG1	728..959	CDD:239862	27/140 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24215
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100