DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15208 and CFAP410

DIOPT Version :9

Sequence 1:NP_001285099.1 Gene:CG15208 / 32022 FlyBaseID:FBgn0030247 Length:365 Species:Drosophila melanogaster
Sequence 2:NP_001258370.1 Gene:CFAP410 / 755 HGNCID:1260 Length:375 Species:Homo sapiens


Alignment Length:389 Identity:115/389 - (29%)
Similarity:164/389 - (42%) Gaps:75/389 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 QLTEHMVESMSRCRDYAKALKLNFCNCGLNDISLCLKMPYLEVLSLSMNKITSLKSLVRCTRLKE 68
            :||..||.:.::..:.....|||.....|.|||:|.:||.|||::||:|.|::|:.:.||.||.|
Human     2 KLTRKMVLTRAKASELHSVRKLNCWGSRLTDISICQEMPSLEVITLSVNSISTLEPVSRCQRLSE 66

  Fly    69 LYLRQNEIADFDELKYLVNAKSLTSLWLLDNPCSIAAGSNYRASVLRMLPNLKKLDNVDVAEEEL 133
            ||||:|.|....||.||.....|..|||.:|||...:...||.:|||.||.|:||||..|.||||
Human    67 LYLRRNRIPSLAELFYLKGLPRLRVLWLAENPCCGTSPHRYRMTVLRTLPRLQKLDNQAVTEEEL 131

  Fly   134 ESAL----RYDYYPD-VGSAILNPVL--DLSNCSPDDMAYRDMIEQCDRTI-----RQVQQQQRK 186
            ..||    .....|: .|:....|.|  .||:.|......||.::..:...     |.::...|.
Human   132 SRALSEGEEITAAPEREGTGHGGPKLCCTLSSLSSAAETGRDPLDSEEEATGAQDERGLKPPSRG 196

  Fly   187 RFASGDAKNIDELARIRSRSVLVNGERLPLFFPSDLRQVRQAQKAQDALRKQKNQPIWH----NE 247
            :|.|..|::.....|.|     |:|..|             ...|..|          |    .|
Human   197 QFPSLSARDASSSHRGR-----VSGGPL-------------GAAAASA----------HCTHCTE 233

  Fly   248 QVQQAHKFTMTPQA-VHEQVQGIQS-------ISSDRNAD---SPAASTSTLAENLIEL------ 295
            .|.:.|..:..|.. .|...||::.       :....||.   :.|...:.||...:.|      
Human   234 TVGREHGASQGPVGREHGASQGLEELCPRGSCVCGSVNAHTRVTRAPHGAVLAPQPLLLSWSVEC 298

  Fly   296 ------INSRRQDVVTPPGHLLPNVSSGLALNGANSTTLERHNNSLSAALLLIQDMNASQLETL 353
                  ....|..|...| |..|  .:||..:.:.|..     |.|:|.|||:::::|..||.:
Human   299 GPGPCWAEGNRSHVEEVP-HTRP--QAGLLCSDSPSVP-----NVLTAILLLLRELDAEGLEAV 354

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15208NP_001285099.1 LRR_4 42..83 CDD:289563 21/40 (53%)
leucine-rich repeat 44..65 CDD:275382 10/20 (50%)
leucine-rich repeat 66..89 CDD:275382 12/22 (55%)
leucine-rich repeat 91..119 CDD:275382 13/27 (48%)
CFAP410NP_001258370.1 LRR_8 19..74 CDD:290566 28/54 (52%)
LRR_4 19..59 CDD:289563 18/39 (46%)
LRR 1 19..40 8/20 (40%)
LRR_4 40..80 CDD:289563 20/39 (51%)
LRR 2 41..62 9/20 (45%)
leucine-rich repeat 42..63 CDD:275382 10/20 (50%)
LRR 3 63..84 12/20 (60%)
leucine-rich repeat 64..87 CDD:275382 12/22 (55%)
leucine-rich repeat 89..117 CDD:275382 13/27 (48%)
LRRcap 104..122 CDD:197729 9/17 (53%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 129..156 7/26 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165141669
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2123
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1021585at2759
OrthoFinder 1 1.000 - - FOG0006546
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR18849
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
76.810

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