DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15208 and F09G8.5

DIOPT Version :9

Sequence 1:	NP_001285099.1	Gene:	CG15208 / 32022	FlyBaseID:	FBgn0030247	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_498812.2	Gene:	F09G8.5 / 184268	WormBaseID:	WBGene00017320	Length:	461	Species:	Caenorhabditis elegans

Alignment Length:	389	Identity:	101/389 - (25%)
Similarity:	169/389 - (43%)	Gaps:	79/389 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QLTEHMVESMSRCRDYAKALKLNFCNCGLNDISLCLKMPYLEVLSLSMNKITSLKSLVRCTRLKE 68
            :|||..|...::| ......|||...||::||.:|.||..|||||||:|::.||..|..|..|||
Worm   103 KLTESAVYIRTKC-SLENVKKLNLWGCGIDDIQVCEKMSLLEVLSLSVNEVKSLAPLQHCKNLKE 166

  Fly    69 LYLRQNEIADFDELKYLVNAKSLTSLWLLDNPCSIAAGSNYRASVLRMLPNLKKLDNVDVA---- 129
            :|||:|.:...|||:||....:|.:||:.:|||....|..||..|:|:||||.|||:..|.
Worm   167 VYLRKNCLESLDELEYLKELPNLRTLWIDENPCVGEGGQEYRRKVIRVLPNLTKLDDKPVTTTDH 231

  Fly   130 EEELESALRYDYYPDVGSAILNPVLDLSNCSPDDMAYR-DMIEQCDRT-------IRQVQQQQRK 186
            :|.:|.::              |..|:.|......:.| :.|:...|:       :.::.|.|..
Worm   232 QEAIEDSI--------------PECDMHNSHYSARSNRSNSIDLMSRSLYVGPTVVDRIVQPQLL 282

  Fly   187 RFASGDAKNIDELARIRSRSVLVNGERLPLFFPSDLRQVRQAQKAQDALRKQKNQPIWHNEQVQQ 251
            .|  ||..: :|.....:||..|....|||                     .::....:.:...|
Worm   283 HF--GDTSD-EERTTYPARSFSVEVPGLPL---------------------TEDHTTVYLDSAPQ 323

  Fly   252 AH---KFTMTPQAVHEQVQGIQ----------------SISSDR-NADSPAASTSTLAENLIE-- 294
            :|   :..:..|:::..:.|..                ||..|| ....|.|::..:.:::.|
Worm   324 SHIGSRHNLMSQSMYGTLCGTLAEEPSSADGEDDWNDFSIEEDRVMVQMPLAASHRMYQSMHEGM 388

  Fly   295 LINSRRQDV----VTPPGHLLPNVSSGLALNGANSTTLERHNNSLSAALLLIQDMNASQLETLV 354
            :|..:|..|    |:.|.....|:::  ..:..:....:|....:||..:|:.:::...|..:|
Worm   389 VIEMKRPPVYGRSVSMPRRRATNLTT--RASSMSPAREQRLTKIMSAVSVLLDELDTDGLRQVV 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15208	NP_001285099.1	LRR_4	42..83	CDD:289563	21/40 (53%)
		leucine-rich repeat	44..65	CDD:275382	12/20 (60%)
		leucine-rich repeat	66..89	CDD:275382	12/22 (55%)
		leucine-rich repeat	91..119	CDD:275382	12/27 (44%)
F09G8.5	NP_498812.2	LRR_4	118..160	CDD:289563	21/41 (51%)
		LRR_4	142..181	CDD:289563	21/38 (55%)
		leucine-rich repeat	142..163	CDD:275382	12/20 (60%)
		leucine-rich repeat	164..187	CDD:275382	12/22 (55%)
		leucine-rich repeat	189..217	CDD:275382	12/27 (44%)
		LRRcap	205..222	CDD:197729	9/16 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156569
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006546
OrthoInspector	1	1.000	-	-		otm14795
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18849
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.800