DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1582 and ABO6

DIOPT Version :9

Sequence 1:	NP_001285098.1	Gene:	CG1582 / 32021	FlyBaseID:	FBgn0030246	Length:	1288	Species:	Drosophila melanogaster
Sequence 2:	NP_680142.2	Gene:	ABO6 / 830371	AraportID:	AT5G04895	Length:	1161	Species:	Arabidopsis thaliana

Alignment Length:	929	Identity:	336/929 - (36%)
Similarity:	512/929 - (55%)	Gaps:	122/929 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   385 AGGGVNPDAEHHQSPKPSHYARGQTSRN--DGGHQRNVEAQTRENRRLLQQFVERRKEERYQKII 447
            :.|..|......|.||.:.....:.|.:  ||.....|..:.....|.:|:..:...|.|  .::
plant   192 SSGKANECVADSQPPKQTEELPDENSDSFLDGSVMEKVLQRRSMRMRNMQRTWQESPEGR--TML 254

  Fly   448 DGRKQLPAFAEIERILALIESSPVVVISGETGCGKSTQVPQFILDNWFFRALQLPAKENLPHVE- 511
            :.||.||:|.:.||:|..|..:.|:|:||||||||:||:||:||::               .:|
plant   255 EFRKTLPSFKDKERLLQAIARNQVIVVSGETGCGKTTQLPQYILES---------------EIES 304

  Fly   512 -------IICTQPRRLSAIGVAERVAAERLDRIGQLVGYQIRLENKVSQSTRLSFCTTGILLRRL 569
                   ||||||||:||:.|:|||:|||.:.:|:.||:::|||....::|.|.|||:|||||||
plant   305 GRGAFCNIICTQPRRISAMAVSERVSAERGEPLGETVGFKVRLEGMRGKNTHLLFCTSGILLRRL 369

  Fly   570 ASDPLLGSVTHVIVDEVHERSEESDFLLLILKNLLRERKDLKVILMSATLNAALFSDYFGGAPVL 634
            .||..|..||||.|||:|||....|||:::||.||..|.||:::||||||||.|||:|:||||.:
plant   370 LSDRNLNGVTHVFVDEIHERGMNEDFLIIVLKELLPRRPDLRLVLMSATLNAELFSNYYGGAPTI 434

  Fly   635 DIPGRTFPVQQLFLEDILEMSDFVM----EYDTKYCRKLKKQEQEILERELEYADVQASGEAPGK 695
            .|||.|.||:..||||:||::.:.:    :.|.....|..|.:::::.|
plant   435 HIPGFTHPVKAHFLEDVLEITGYKLTSFNQVDDYGQEKTWKTQKQLMPR---------------- 483

  Fly   696 KIKDEKLTLAE---TYQRYAEYSKPTCKSIYLMEPMTINPELIESVLKYIVEGSHDWPREGTILI 757
            |.|::..||.|   :...:..|:..|..|:....|..|...|||:||.:|....    |.|.:|:
plant   484 KRKNQITTLVEEALSKSNFESYNSRTRDSLSSWMPDCIGFNLIEAVLCHICRKE----RPGAVLV 544

  Fly   758 FLPGFGEIQSVHDSLLDNALFSPRAGKFILVPLHSALSGEDQALVFKKAPPGKRKIVLSTNIAET 822
            ||.|:.:|:|:.|.:..:.|... ..:.:|:..|.:::..:|.|:|::|||..|||||:||:||.
plant   545 FLTGWDDIRSLSDQIKAHPLLGD-PNRVLLLMCHGSMATAEQRLIFERAPPNIRKIVLATNMAEA 608

  Fly   823 SVTIDDCVFVVDCGLMKEKCFDSNRNMESLDLVWVSRANAKQRKGRAGRVMPGVCIHLYTSYRY- 886
            |:||:|.|||||||..||..:|:..|...|...|:|:|:|:||:|||||:.||.|.|||....|
plant   609 SITINDVVFVVDCGKAKETTYDALNNTPCLLPSWISQASARQRRGRAGRLFPGECYHLYPKCVYD 673

  Fly   887 ---QYHILAQPVPEIQRVPLEQIVLRIKTLQTFASRNTLSVLLETLEAPTEDSVLGALTRLRDVG 948
               :|.:     ||:.|.||..:.|:||:||..:....||.   .|:||...:|..|:..|:.:|
plant   674 AFAEYQL-----PELLRTPLNSLCLQIKSLQVESIAEFLSA---ALQAPESLAVQNAIGFLKMIG 730

  Fly   949 ALDAEDQLTPLGHHLAALPVDVRIGKLMLYGAIFQCLDSVLTIAACLSNKSPFVSPLNKRTEADK 1013
            |||.::.||.||..|:.||||.::||:::.||||:|.|.:|||.:.||.:.||:.|.:|:..|..
plant   731 ALDEKENLTDLGKLLSILPVDPKLGKMLIMGAIFRCFDPILTIVSGLSVRDPFLLPQDKKDLALS 795

  Fly  1014 CK-RMFALGNSDHLTVLNAYRKWLDVARRGNYAASRNYASEHFLSLNTLETIADLKYQYLELLVS 1077
            .| |..|...|||:.::.|:..|.|..|.|   ::..:...:|||..||:.|..|:.|:..:|..
plant   796 AKLRFSAKDYSDHMALVRAFEGWKDAEREG---SAYEFCWRNFLSAQTLQAIHSLRKQFNYILKE 857

  Fly  1078 IGFVPIDVPRRRKNACDNILTLTGVEQNHNGDNNRLLTSLLCAALYPNIVKIMTPDRVYIQTAGG 1142
            .|.|..|:      |.:|.|:          .|..|:.:::|:.|:|.|..:
plant   858 AGLVHDDL------ALNNKLS----------HNQSLVRAVICSGLFPGIASV------------- 893

  Fly  1143 AVPREPSHHDLRFKTRGDGYVKIHPSSVNSQVSVFQAPFLVFQEKVRTSAIYIRDCSMLPLIAMV 1207
             |.||.|   :.|||..||.|.::.:||||:......|:|||.|||:.:|:.|||.:.:|..:::
plant   894 -VHRETS---MSFKTMDDGQVSLYANSVNSRFPTIPYPWLVFGEKVKVNAVLIRDSTGVPDSSLI 954

  Fly  1208 LFAGS------DFKVELHDGDFLFLLESGWIILKAHDLETAEMVQCLRAEMIKLLEEKIRDPCLN 1266
            ||.||      ...:::.||...|.:          |...||....|:.|:.|||::|:.||.::
plant   955 LFGGSLSTGVQVGHLKMLDGYIDFFM----------DPNLAESYVKLKEELDKLLQKKLEDPSMD 1009

  Fly  1267 LLHHKNGCRMIANIVHLIS 1285
            :  ||.|..::..:..|::
plant  1010 I--HKEGKYLMLAVQELVA 1026

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1582	NP_001285098.1	UBA_like_SF	123..154	CDD:304366
		zf-CCCH	250..272	CDD:279036
		RWD	<284..360	CDD:283440
		HrpA	419..1206	CDD:224557	306/806 (38%)
		DEXDc	471..619	CDD:238005	79/155 (51%)
		HELICc	781..871	CDD:197757	42/89 (47%)
		HA2	948..1029	CDD:214852	37/81 (46%)
		OB_NTP_bind	1070..1212	CDD:285018	42/141 (30%)
ABO6	NP_680142.2	HrpA	238..1007	CDD:224557	322/860 (37%)
		P-loop_NTPase	<247..>291	CDD:304359	21/45 (47%)
		DEXDc	277..419	CDD:238005	79/156 (51%)
		Helicase_C	529..621	CDD:278689	38/96 (40%)
		HA2	728..812	CDD:214852	37/83 (45%)
		OB_NTP_bind	849..960	CDD:285018	43/143 (30%)
		DSRM	1059..1122	CDD:238007
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1108
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	558	1.000	Inparanoid score	I250
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278674at2759
OrthoFinder	1	1.000	-	-		FOG0000258
OrthoInspector	1	1.000	-	-		otm3120
orthoMCL	1	0.900	-	-		OOG6_100595
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X384
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.770