Protein Alignment CG1582 and Dhx16

DIOPT Version :10

• Sequence 1: NP_572663.1
• Gene: CG1582 / 32021
• FlyBaseID: FBgn0030246
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: XP_006524936.1
• Gene: Dhx16 / 69192
• MGIID: 1916442
• Length: 1049
• Species: Mus musculus
• Alignment Length: 1209
• Identity: 329/1209 - (27%)
• Similarity: 499/1209 - (41%)
• Gaps: 351/1209 - (29%)

  Fly   120 RYALAKLE-NYGFQAVHCLEAYEHCSGDTEAALLLLYRRYMRI--------PDEEQLTLE----- 170
            |.|.|.|| |..::.:...|:.|...|...::|....:|...:        .|||:...|
Mouse    85 REARALLEKNRSYKLLEDSESGEEAVGSNGSSLQKKRKRRKHLRKKHQEDEEDEEEEVSESGKRK 149

  Fly   171 -----------PPSEQEILDMRADEKEALESI-----FDKAYEEREANRVWNLKFRIDHLLAHSP 219
                       |.||.|   ....|:|.|:.:     |.:...:|:.:|..|:..|.|
Mouse   150 AGGSKSPTEEKPASEDE---WERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSD------- 204

  Fly   220 SEVRKAREAVLAAAAAAAQAALDKKKK-PPLRCRNFDRDGTCKYGPKCRFAHLPQQPTESDTTKK 283
               :||.|   .|......|..|:|.. |.||             .|.|..:|.::..|    |.
Mouse   205 ---KKAYE---EAQKRLKMAEEDRKAMVPELR-------------KKSRREYLAKRERE----KL 246

  Fly   284 DSVDEN--DNELWF-HVEVRFPPGSRYPYEAPFIYLKTTCHDIPHELR-LRYARHLYKEAKEICR 344
            :.::..  |.|:.| .||:     ||                  ||.| |:|.|.:...|:|...
Mouse   247 EDLEAELADEEVLFGDVEL-----SR------------------HERRELKYKRRVRDLAREYRA 288

  Fly   345 DGIPCVYSICDLLQSNEQLAGRLDTSAFPSPKRSLFYDEPAGGGVNPDAEHHQSPKPSHYAR--- 406
            .|            ..|:|..   |:.:..||.:  ..:||.   ..|....:|..|....|
Mouse   289 AG------------EQEKLEA---TNRYHMPKET--RGQPAR---TVDIVEEESGAPGEEQRRWE 333

  Fly   407 ----GQTSRNDGGHQRNVEAQTRENRRLLQ-----QFV------------------ERRKEERYQ 444
                |..|...|.  |:..||..:.:.:|:     :||                  :.:::|..|
Mouse   334 EAQLGAASLKFGA--RDAAAQEAKYQLVLEEDETIEFVRAAQLQGDEEPSGPPLSAQAQQKESIQ 396

  Fly   445 KIIDGRKQLPAFAEIERILALIESSPVVVISGETGCGKSTQVPQFILDNWFFRALQLPAKENLPH 509
            .:   |:.||.|...|.:||.|.:..|::|.||||.||:||:||::.:..:       .|:.:
Mouse   397 AV---RRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGY-------TKKGM-- 449

  Fly   510 VEIICTQPRRLSAIGVAERVAAERLDRIGQLVGYQIRLENKVSQSTRLSFCTTGILLRRLASDPL 574
             :|.||||||::|:.||.|||.|...::|..|||.||.|:..|:.|.|.:.|.|:|||...|:|.
Mouse   450 -KIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPD 513

  Fly   575 LGSVTHVIVDEVHERSEESDFLLLILKNLLRERKDLKVILMSATLNAALFSDYFGGAPVLDIPGR 639
            |.|.:.|:|||.|||:..:|.|..::|::.|.|.:|||::.||||:.|.||.:|..|||..||||
Mouse   514 LASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATLDTARFSAFFDDAPVFRIPGR 578

  Fly   640 TFPVQQLFLEDILEMSDFVMEYDTKYCRKLKKQEQEILERELEYADVQASGEAPGKKIKDEKLTL 704
            .|||...:                     .|..|.:.||
Mouse   579 RFPVDIFY---------------------TKAPEADYLE-------------------------- 596

  Fly   705 AETYQRYAEYSKPTCKSIYLMEPMTINPELIESVLKYIVEGSHDWPREGTILIFLPG-----FGE 764
                         .|               :.|||:.     |.....|.||:||.|     ..|
Mouse   597 -------------AC---------------VVSVLQI-----HVTQPPGDILVFLTGQVSAVVEE 628

  Fly   765 IQSVHDSLLDNA-LFSPRAGKFILVPLHSALSGEDQALVFKKAPPGKRKIVLSTNIAETSVTIDD 828
            |::..:.|.|.. ....:..:.:::|:::.|..:.||.:|:..|||.||:|::|||||||:||:.
Mouse   629 IEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEG 693

  Fly   829 CVFVVDCGLMKEKCFDSNRNMESLDLVWVSRANAKQRKGRAGRVMPGVCIHLYTSYRYQYHILAQ 893
            .::|:|.|..|:|.::....||||.:...|:|:|.||.||||||..|.|..|||::.||:.:...
Mouse   694 IIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEET 758

  Fly   894 PVPEIQRVPLEQIVLRIKTLQTFASRNTLSVLLETLEAPTEDSVLGALTRLRDVGALDAEDQLTP 958
            .||||||..|..:||.:|:|......:     .:.|:.|..:::|.||.:|..:|||:...:||.
Mouse   759 TVPEIQRTSLGNVVLLLKSLGIHDLMH-----FDFLDPPPYETLLLALEQLYALGALNHLGELTT 818

  Fly   959 LGHHLAALPVDVRIGKLMLYGAIFQCLDSVLTIAACLS-NKSPFVSPLNKRTEADKCKRMFALGN 1022
            .|..:|.||||..:.|::|....:.|.:.:||:||.|| |.|.|..|.:|...||..:..|.|..
Mouse   819 SGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPG 883

  Fly  1023 SDHLTVLNAYRKWLDVARRGNYAASRNYASEHFLSLNTLETIADLKYQYLELL--VSIGFVPIDV 1085
            .|||.:||.|.:|.:    ..|  |..:..|:|:...::....|::.|...||  |.:|
Mouse   884 GDHLVLLNVYTQWAE----SGY--SSQWCYENFVQFRSMRRARDVREQLEGLLERVEVG------ 936

  Fly  1086 PRRRKNACDNILTLTGVEQNHNGDNNRLLTSLLCAALYPNIVKIMTPDRVYIQTAGGAVPREPSH 1150
                                        |||  |...|..:.|.:|....|
Mouse   937 ----------------------------LTS--CQGDYVRVRKAITSGYFY-------------- 957

  Fly  1151 HDLRFKTRGDGYVK------IHPSSVNSQVSVF--QAPFLVFQEKVRTSAIYIRDCSMLPLIAMV 1207
            |..|....|...||      |||:|     |:|  |..:|::.|.|.|:..::|.
Mouse   958 HTARLTRSGYRTVKQQQTVFIHPNS-----SLFEQQPRWLLYHELVLTTKEFMRQ---------- 1007

  Fly  1208 LFAGSDFKVELHDGDFLFLLESGWII------LKAHDLE 1240
                            :..:||.|::      .||.:||
Mouse  1008 ----------------VLEIESSWLLEVAPHYYKAKELE 1030

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1582	NP_572663.1	UBA_like_SF	123..154	CDD:473871	8/31 (26%)
		RWD_DHX57	175..367	CDD:467661	43/201 (21%)
		zf-CCCH	245..272	CDD:459885	5/27 (19%)
		HrpA	452..>1075	CDD:441249	211/629 (34%)
		OB_NTP_bind	1114..1212	CDD:400182	25/105 (24%)
Dhx16	XP_006524936.1	PTZ00121	<147..>410	CDD:173412	70/343 (20%)
		HrpA	401..>1033	CDD:441249	247/812 (30%)