Protein Alignment CG1582 and dhx30

DIOPT Version :10

• Sequence 1: NP_572663.1
• Gene: CG1582 / 32021
• FlyBaseID: FBgn0030246
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: XP_699339.5
• Gene: dhx30 / 570735
• ZFINID: ZDB-GENE-130530-833
• Length: 1173
• Species: Danio rerio
• Alignment Length: 1311
• Identity: 377/1311 - (28%)
• Similarity: 596/1311 - (45%)
• Gaps: 242/1311 - (18%)

  Fly    15 RSPSDIRTTNVPAAPKSQAADNKSRKTELHVLRLNDESRQMTMDTLRQIHGPEFQLDDISKYKDR 79
            ||..|:..|...:.|::   .||:....||       ::.:..:||.:..|    |.::|:|...
Zfish    38 RSKPDVVHTRRHSPPET---INKAHPDYLH-------AKNLLYNTLSRSVG----LSNVSQYLKF 88

  Fly    80 GRGGHGVKHS----YWQDRGTLVVQSVQGVSSTRGNDSDGDRLRRYALAKLENYGFQAVHCLEAY 140
            ......||.:    .|..|           ..|.|..|......|.|.|.    ..|.:..|..|
Zfish    89 SCTDGEVKRATVTLLWPVR-----------IETEGFGSRKQEAERNAAAA----ALQKLCELGVY 138

  Fly   141 EHCSGDTEAALLLLYRRYMRIPDEEQLTLEPPSEQEILDMRADEKEALESI-FDKAYEEREANRV 204
            .......||.:|.:..|...:.|.|                  |:..|:|: ..|..::..|:.:
Zfish   139 APGKRRQEAGMLRMKDRQTSLCDNE------------------EENHLQSLPIQKKTQKDRAHGL 185

  Fly   205 WNLKFRIDHLLAHSPSEVRKAREAVLAAAAAAAQAALDKKKKPPLRCRNFDRDGTCKYGPKCRFA 269
            .....|:...||..| ..|....:|:..|.::                             ||..
Zfish   186 VEEDSRLSEALAIFP-RPRTLLGSVIQVATSS-----------------------------CRVR 220

  Fly   270 HLPQQPTESDTTKKDSVDENDNELWFHVEVRFPPGSRYPYEAPFIYLKTTCHDIPHELRL----- 329
            .|.|..|.....|...:    |.|| ...:.|....|...||........|..: .||.|
Zfish   221 DLLQYKTSGGKVKVCEL----NVLW-PTPMTFTASGRRRLEAEANAAALACLKL-KELNLLDEQN 279

  Fly   330 ------RYARHLYKEAKEICRDGIPCVYSICDLLQSNEQLAGRLD--TSAFP--SPKRSLFYDEP 384
                  ||.:...:||.|  |...||      .:|..|||..|:.  .|.:|  :..:.|:
Zfish   280 KPLTHARYHQDQVREAGE--RHRQPC------RMQIPEQLELRIQQYLSQYPVEAEVQKLW---- 332

  Fly   385 AGGGVNPDAEHHQSPKPSHYARGQTSRNDGGHQRNV-EAQTRENRRLLQ----QFVERRKEERYQ 444
                   |.|.|||...|      |:.:|......: :|.|.:..|.|:    :.:.:|....::
Zfish   333 -------DEEEHQSSSIS------TAADDYDEDEFITDAITSKPYRALEPKEAEHLSQRLLSMWK 384

  Fly   445 KIIDGR-KQLPAFAEIERILALIESSPVVVISGETGCGKSTQVPQFILDNWFFRALQLPAKENLP 508
            ::...| .:||..|..|.||..:.||.||||||||||||:|::|:|:|::...|.       ...
Zfish   385 RVGPARGAELPVDAHKESILEAVRSSQVVVISGETGCGKTTRIPRFLLEDGVLRG-------EGA 442

  Fly   509 HVEIICTQPRRLSAIGVAERVAAERLDRIGQLVGYQIRLENKVSQST--RLSFCTTGILLRRLAS 571
            ...::.|||||:||:.||:|||.|....:...||||:|||::..:.:  .|.|.|.|:||::|.|
Zfish   443 ECNVLVTQPRRISAVSVAQRVAHEIGPALQHCVGYQVRLESRPPERSGGALLFLTLGVLLKKLQS 507

  Fly   572 DPLLGSVTHVIVDEVHERSEESDFLLLILKNLLRERKDLKVILMSATLNAALFSDYFGGAPVLDI 636
            :|.|..::||||||||||..::|.||.:|:.:|..|.:|||:||||:.::...:.||||.|||.:
Zfish   508 NPRLEGISHVIVDEVHERDVQTDLLLHLLRCVLSLRPELKVLLMSASGDSQRLAQYFGGCPVLRV 572

  Fly   637 PGRTFPVQQLFLEDILEMSDFVMEYDTKYCRKLKKQEQEILERELEYADVQASGEAPGKKIKDEK 701
            ||...||:..||||        |:.|::  |.|           |:....|.|.|..|:..|:|.
Zfish   573 PGFMHPVRARFLED--------MQLDSR--RPL-----------LDMGSTQWSAEVRGRMGKEEN 616

  Fly   702 LTLAETYQRYAEYSKPTCKSIYLMEPMTINPELIESVLKYIVEGSHDWPREGTILIFLPGFGEIQ 766
                                       .:.|:|  .::..:::..|.....|.:|.||||:.||:
Zfish   617 ---------------------------NVTPDL--DLVADVIDHIHRTGEPGAVLCFLPGWQEIK 652

  Fly   767 SVHDSLLDNALFSPRAGKFILVPLHSALSGEDQALVFKKAPPGKRKIVLSTNIAETSVTIDDCVF 831
            :|...|.:...:  |:|..|::||||:::..:|.:||::.|.|:|||||:|||||||:||||.|.
Zfish   653 AVQQQLEEKQAY--RSGSQIILPLHSSMAVSEQQVVFQRPPAGQRKIVLATNIAETSITIDDIVH 715

  Fly   832 VVDCGLMKEKCFDSNRNMESLDLVWVSRANAKQRKGRAGRVMPGVCIHLYTSYRYQYHILAQ-PV 895
            |||.|:.||:.:|....:.:|:.||:|:||..||:|||||..||...||:.  |.|...:.. ||
Zfish   716 VVDAGVQKEQNYDPRTKVSALNTVWISQANVTQRRGRAGRCQPGHSYHLFP--RKQLERMEPFPV 778

  Fly   896 PEIQRVPLEQIVLRIK------TLQTFASRNTLSVLLETLEAPTEDSVLGALTRLRDVGALDAED 954
            |||.|.|||.:|::.|      ..:.|.|        :.|::|...:|..|:..|.|:|.|||.:
Zfish   779 PEILRTPLESVVMQAKIHCPESKAEDFLS--------QVLDSPDTQAVRTAVKNLMDIGVLDASE 835

  Fly   955 QLTPLGHHLAALPVDVRIGKLMLYGAIFQCLDSVLTIAACLSNKSPFVSPLNKRTEADKCK-RMF 1018
            .|||||||::.:..|.|:||::::.|:|.|:..||::.|||: :.||.:.|..||...|.| .:.
Zfish   836 DLTPLGHHVSCMSCDPRLGKVLVFSALFSCVQPVLSVVACLT-RDPFYNSLQNRTLVSKAKAELS 899

  Fly  1019 ALGNSDHLTVLNAYRKWLDVARRGNYAASRNYASEHFLSLNTLETIADLKYQYLELLVSIGFVPI 1083
            ....||:|......:.|.:...|.   :.::|..:|.||..:|..|..|..|:.:.|...|.|..
Zfish   900 GSSGSDYLVFSRVVQSWREQHSRD---SRQDYLDKHTLSGASLRFIHGLMQQFSDNLCEAGLVDH 961

  Fly  1084 DVPRRRKNACDNILTLTGVEQNHNGDNNRLLTSLLCAALYPNIVKIMTPDRVYIQTAGGAVPREP 1148
            .....|.::          ..|......:|:|::|.|.||||::::    :..:.|..|....|
Zfish   962 SAECLRLSS----------PVNQQSKEEQLITAVLLAGLYPNLIQV----KKGVVTKSGRFRAE- 1011

  Fly  1149 SHHDLRFKTRGDGYVKIHPSSVNSQVSVFQAPFLVFQEKVRTSA-IYIRDCSMLPLIAMVLFAGS 1212
               ::.|:|. .|.|.:|.||||.......:.:|.|...|::|. ::|||.:::..:|::|....
Zfish  1012 ---NVSFRTE-SGPVLLHRSSVNRDKQHLWSRWLTFFSAVKSSGQVFIRDSTVVHPLALLLLTDC 1072

  Fly  1213 DFKVELHDGDFLFLLESGWIILKAHDLETA--EMVQCLRAEMIKLLEEKIR-DPCLNLLHHKNGC 1274
            |.. |...||.:.:...|..::: .:...|  |::..|||.:..::..|:| ..|.:....:...
Zfish  1073 DLS-ERVVGDRVEVALPGPALIR-WEFSPAVWELLWDLRASIQAMIYRKLRQSECKSSSEQRKDS 1135

  Fly  1275 RMIANIVHLIS 1285
            .:|..:|.|::
Zfish  1136 ELIDLLVDLLN 1146

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1582	NP_572663.1	UBA_like_SF	123..154	CDD:473871	7/30 (23%)
		RWD_DHX57	175..367	CDD:467661	41/203 (20%)
		zf-CCCH	245..272	CDD:459885	2/26 (8%)
		HrpA	452..>1075	CDD:441249	234/632 (37%)
		OB_NTP_bind	1114..1212	CDD:400182	28/98 (29%)
dhx30	XP_699339.5	HrpA	388..>930	CDD:441249	228/614 (37%)
		OB_NTP_bind	982..1069	CDD:400182	27/95 (28%)