Protein Alignment CG1582 and l(2)37Cb

DIOPT Version :10

• Sequence 1: NP_572663.1
• Gene: CG1582 / 32021
• FlyBaseID: FBgn0030246
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: NP_609946.1
• Gene: l(2)37Cb / 35192
• FlyBaseID: FBgn0086444
• Length: 894
• Species: Drosophila melanogaster
• Alignment Length: 1075
• Identity: 292/1075 - (27%)
• Similarity: 458/1075 - (42%)
• Gaps: 301/1075 - (28%)

  Fly   267 RFAHLPQQPTESDTTKKDSVDENDNELWFHVEVRFPPGSRYPYEAPFIYLKTTCHD----IPHEL 327
            |...|.::...:...||...|...|       |....|.|...|.....||....|    :|| |
  Fly    26 RLKDLQERDEFASRLKKRDDDRTRN-------VVDSTGGRRAIEEATKRLKLEHEDRDKIVPH-L 82

  Fly   328 RLRYARHLYKEAKEICRDGIPCVYSICDLLQSNEQLAGRLDTSAFPSPKRSLFYDEPAGGGVNPD 392
            ||:..|...::.|:   |.:..:.:  |:| .:|.|   .|.|..  .||.....|.....:|..
  Fly    83 RLQSRRQYLEKRKD---DKVAELEA--DIL-DDEYL---FDESVL--TKREKEEREYKKQLLNIA 136

  Fly   393 AEHHQSPK---------PSHYARGQTS---------RNDGGHQRNVEAQTRENRRLLQQFVERRK 439
            .||.::.:         |....:|:.|         :.....|:..||:...:.|......:.:.
  Fly   137 KEHEKARELERIQRYNMPQDLKKGERSEYVEVDEFEKQPNSEQKKWEAEQLASARFHFGAKDAKA 201

  Fly   440 EERYQKIIDG-------------------------------------RKQLPAFAEIERILALIE 467
            ||.|:.::|.                                     |:.||.:...|.::|.::
  Fly   202 EEEYELLLDDQIDFIQALTLDGSREKSSSRQPELTEKERKRLTLDETRRSLPVYPFKEDLIAAVK 266

  Fly   468 SSPVVVISGETGCGKSTQVPQFILDNWFFRALQLPAKENLPHVEIICTQPRRLSAIGVAERVAAE 532
            ...|::|.||||.||:|||||::::..|.:..::          |.||||||::|:.||.|||.|
  Fly   267 EHQVLIIEGETGSGKTTQVPQYLVEAGFTKDKKM----------IGCTQPRRVAAMSVAARVAEE 321

  Fly   533 RLDRIGQLVGYQIRLENKVSQSTRLSFCTTGILLRRLASDPLLGSVTHVIVDEVHERSEESDFLL 597
            ...::|..|||.||.|:..|..|.|.:.|.|.|.|...|:|.|.|.:.:|:||.|||:..:|.|.
  Fly   322 MGVKLGNEVGYSIRFEDCTSDRTILKYMTDGTLHREFLSEPDLASYSVMIIDEAHERTLHTDILF 386

  Fly   598 LILKNLLRERKDLKVILMSATLNAALFSDYFGGAPVLDIPGRTFPVQQLFLEDILEMSDFVMEYD 662
            .::|::.|.|.:||:::.||||:|..||.:|..||:..||||.:||      ||         :.
  Fly   387 GLVKDIARFRPELKLLISSATLDAEKFSAFFDDAPIFRIPGRRYPV------DI---------FY 436

  Fly   663 TKYCRKLKKQEQEILERELEYADVQASGEAPGKKIKDEKLTLAETYQRYAEYSKPTCKS---IYL 724
            ||                           ||                 .|:|....|.|   |:.
  Fly   437 TK---------------------------AP-----------------EADYIDACCVSVLQIHA 457

  Fly   725 MEPMTINPELIESVLKYIVEGSHDWPREGTILIFLPGFGEIQSVHDSLLDNALFSPRAG----KF 785
            .:|:                        |.||:||.|..||::..:.|.|..   .|.|    :.
  Fly   458 TQPL------------------------GDILVFLTGQDEIETCQEVLHDRV---KRLGSKIREL 495

  Fly   786 ILVPLHSALSGEDQALVFKKAPPGKRKIVLSTNIAETSVTIDDCVFVVDCGLMKEKCFDSNRNME 850
            |::|:::.|..:.||.:|:..||..||::|:|||||||:|||:.::|:|.|..|:..|:|...||
  Fly   496 IVIPVYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQNNFNSRTGME 560

  Fly   851 SLDLVWVSRANAKQRKGRAGRVMPGVCIHLYTSYRYQYHILAQPVPEIQRVPLEQIVLRIKTLQT 915
            ||.:|.:|:|:|.||.|||||..||.|..|||::.|::.:....||||||:.|...||.:|.|
  Fly   561 SLMVVPISKASANQRAGRAGRTAPGKCFRLYTAWAYKHELEDNTVPEIQRINLGNAVLMLKAL-- 623

  Fly   916 FASRNTLSVLLETLEAPTEDSVLGALTRLRDVGALDAEDQLTPLGHHLAALPVDVRIGKLMLYGA 980
              ..|.| :..:.|:.|..::::.||.:|..:|||:...:||.||..:|..|||..:||::|...
  Fly   624 --GINDL-IHFDFLDPPPHETLVLALEQLYALGALNHHGELTKLGRRMAEFPVDPMMGKMLLASE 685

  Fly   981 IFQCLDSVLTIAACLS-NKSPFVSPLNKRTEADKCKRMFALGNSDHLTVLNAYRKWLDVARRGNY 1044
            .::|.:.::||||.|| |.:.|..|.:|...||..::.|...:.|||::|..|.:|.:.    :|
  Fly   686 KYKCSEEMVTIAAMLSVNSAIFYRPKDKIIHADTARKNFNHMHGDHLSLLQVYNQWAET----DY 746

  Fly  1045 AASRNYASEHFLSLNTLETIADLKYQYLELLVSIGFVPIDVPRRRKNACDNILTLTGVEQNHNGD 1109
              |..:..|:|:...:::...|::.|.:.|:..   |.||:
  Fly   747 --STQWCYENFIQYRSMKRARDVREQLVGLMQR---VEIDM------------------------ 782

  Fly  1110 NNRLLTSLLCAALYPNIVKIMTPDRVYIQTAGGAVPREPSHHDLRFKTRGDGY--------VKIH 1166
                   :.|.....|:.|..|....|              |..|. ::|..|        |.||
  Fly   783 -------VSCLPETVNVRKAATAGYFY--------------HVARL-SKGGHYKTIKHNQTVMIH 825

  Fly  1167 PSSVNSQVSVFQ--APFLVFQEKVRTSAIYIRDCSMLPLIAMVLFAGSDFKVELHDGDFLFLLES 1229
            |:|     |:|:  ..::::.|.|.||..|:|.                          :..:||
  Fly   826 PNS-----SLFEELPRWVLYHELVFTSKEYMRQ--------------------------VIEIES 859

  Fly  1230 GWII------LKAHDLE------------TAEMVQ 1246
            .|::      .||.:||            .|||.|
  Fly   860 KWLLEVAPHYYKAKELEDSTNKKMPKVAGRAEMAQ 894

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1582	NP_572663.1	UBA_like_SF	123..154	CDD:473871
		RWD_DHX57	175..367	CDD:467661	25/103 (24%)
		zf-CCCH	245..272	CDD:459885	1/4 (25%)
		HrpA	452..>1075	CDD:441249	210/630 (33%)
		OB_NTP_bind	1114..1212	CDD:400182	22/107 (21%)
l(2)37Cb	NP_609946.1	PTZ00121	<6..267	CDD:173412	49/259 (19%)
		HrpA	251..>868	CDD:441249	239/803 (30%)