Protein Alignment CG1582 and Dhx38

DIOPT Version :10

• Sequence 1: NP_572663.1
• Gene: CG1582 / 32021
• FlyBaseID: FBgn0030246
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: NP_001386123.1
• Gene: Dhx38 / 292007
• RGDID: 1310345
• Length: 1227
• Species: Rattus norvegicus
• Alignment Length: 1348
• Identity: 333/1348 - (24%)
• Similarity: 540/1348 - (40%)
• Gaps: 356/1348 - (26%)

  Fly     4 SSR--KHMEDCFLRSPS------------------DIRTTNVPAAPKSQAADNKSRKTELHVLRL 48
            |||  :|.....:.:||                  |.|...|.|:.|    ::|.||.|..  |.
  Rat   103 SSRRDRHYRSARVETPSHPGGVSEEFWERSRQRERDRREHGVYASSK----EDKDRKKEKS--RD 161

  Fly    49 NDESRQMTMDTL-RQIHGPEFQLDDISKYKDRGRGGHGVKH----------SYWQDRGTLVVQSV 102
            .|..|:...|.. |..|....:.|..|:...|.......:|          |.|::..:
  Rat   162 RDHDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDS------ 220

  Fly   103 QGVSSTRGND----------SDGDRLRRYALAKLENYGFQAVHCLEAYEHCSGDTEAALLLLYRR 157
             |..|:|.:.          .|.:|..|.:....:.         ......|.||  .|.....:
  Rat   221 -GYGSSRRSQWETPSPTPSYRDSERSHRPSTRDRDR---------SVRSKSSDDT--PLPTPSYK 273

  Fly   158 YMRIPDEEQLTLEPPSEQEILDMRADEKEALESIFDKAYE-------EREANRVWNLKFRID--- 212
            |....|:.:.....|........|.|.:|.:  .||...|       :|:|:|.|   :.:|
  Rat   274 YNEWADDRRHLGSTPRLSRGRGRREDGEEGI--AFDTEEERQQWEDDQRQADRDW---YMMDEGY 333

  Fly   213 ----HLLAHSPSEVRKAREAVLAAAAAAAQAALDKKKKPPLRCRNFDRDGTCKYGPKCRFAHLPQ 273
                :.||:|..:..:.||..|..         .|:|:...:.|..:.|..       |:.  ..
  Rat   334 DEFHNPLAYSSEDYVRRREQHLHK---------QKQKRISAQRRQINEDNE-------RWE--TN 380

  Fly   274 QPTESDTTKKDSVDEN---DNELWFHVEVR--FPP-------GSRYPYEAPFIYLKTTCHDIPHE 326
            :...|....:..|||:   ||....|:.|.  .||       .::.|  .|.|.:|....|:
  Rat   381 RMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQP--EPVIPVKDATSDL--- 440

  Fly   327 LRLRYARHLYKEAKEICRDGIPCVYSICDLLQSNEQLAGRLDTSAFPSPKRSLFYDEPAGGGVNP 391
                         ..|.|.|...|      .:..||...|
  Rat   441 -------------AIIARKGSQTV------RKHREQKERR------------------------- 461

  Fly   392 DAEHHQSPKPSHYARGQTSRND-GGHQRNVE---AQTRENR---RLLQQFVERRKEE-------- 441
            .|:|      .|:....|...| .|.::..|   |.|.:.:   |..|:|.:..||:
  Rat   462 KAQH------KHWELAGTKLGDIMGVKKEEEPDKAMTEDGKVDYRTEQKFADHMKEKSEASSEFA 520

  Fly   442 RYQKIIDGRKQLPAFAEIERILALIESSPVVVISGETGCGKSTQVPQFILDNWFFRALQLPAKEN 506
            :.:.|::.|:.||.||..:.:|.:|..:.:|::.||||.||:||:.|::..:.:
  Rat   521 KKKSILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHQDGY----------- 574

  Fly   507 LPHVEIICTQPRRLSAIGVAERVAAERLDRIGQLVGYQIRLENKVSQSTRLSFCTTGILLRRLAS 571
            ..:..|.||||||::|:.||:||:.|....:|:.|||.||.|:..|::|.:.:.|.|||||....
  Rat   575 TDYGMIGCTQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLR 639

  Fly   572 DPLLGSVTHVIVDEVHERSEESDFLLLILKNLLRERKDLKVILMSATLNAALFSDYFGGAPVLDI 636
            :..|...:.:|:||.||||..:|.|..:|:.::..|.|||:|:.|||::|..|:.:||..|:..|
  Rat   640 EADLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLIVTSATMDADKFAAFFGNVPIFHI 704

  Fly   637 PGRTFPVQQLFLEDILEMSDFVMEYDTKYCRKLKKQEQEILERELEYA-DVQASGEAPGKKIKDE 700
            |||||||..||                     .|..:::.:|..::.: .|..|| ||
  Rat   705 PGRTFPVDILF---------------------SKTPQEDYVEAAVKQSLQVHLSG-AP------- 740

  Fly   701 KLTLAETYQRYAEYSKPTCKSIYLMEPMTINPELIESVLKYIVEGSHDWPREGTILIFLPGFGEI 765
                                                                |.||||:||..:|
  Rat   741 ----------------------------------------------------GDILIFMPGQEDI 753

  Fly   766 QSVHDSLLDNALFSPRAGKFILVPLHSALSGEDQALVFKKAPPGKRKIVLSTNIAETSVTIDDCV 830
            :...|.::::......|....::|::|.|..:.||.:|:|||.|.||.:::|||||||:|:|..:
  Rat   754 EVTSDQIVEHLEELENAPALAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIM 818

  Fly   831 FVVDCGLMKEKCFDSNRNMESLDLVWVSRANAKQRKGRAGRVMPGVCIHLYTSYRYQYHILAQPV 895
            ||:|.|..|.|.|:....|::|.:..:|:|||.||.|||||..||.|..|||...|:..:|...|
  Rat   819 FVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTV 883

  Fly   896 PEIQRVPLEQIVLRIKTLQTFASRNTLSVLLE--TLEAPTEDSVLGALTRLRDVGALDAEDQLTP 958
            |||||..|..:||.:|:|       .:..||:  .::.|.||::|.::.:|..:||||....||.
  Rat   884 PEIQRTNLANVVLLLKSL-------GVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTS 941

  Fly   959 LGHHLAALPVDVRIGKLMLYGAIFQCLDSVLTIAACLSNKSPFVSPLNKRTEADKCKRMFALGNS 1023
            .|..:...|:|..:.|:::......|...:|.|.:.||..:.|..|..:..|:|:.:..||:..|
  Rat   942 TGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPES 1006

  Fly  1024 DHLTVLNAYRKWLDVARRGNYAASRNYASEHFLSLNTLETIADLKYQYLELLVSIGFVPIDVPRR 1088
            ||||.||.|.:|    :..||  |..:.::||:....:..:.:::.|..:::|.        .|.
  Rat  1007 DHLTYLNVYLQW----KNNNY--STIWCNDHFIHAKAMRKVREVRAQLKDIMVQ--------QRM 1057

  Fly  1089 RKNACDNILTLTGVEQNHNGDNNRLLTSLLCAALYPNIVKIM-TPDRVYIQTAGGAVPREPSHHD 1152
            ...:|              |.:..::...:|||.:....|:. ..:.|.|:|.      .|.|
  Rat  1058 SLASC--------------GTDWDIVRKCICAAYFHQAAKLKGIGEYVNIRTG------MPCH-- 1100

  Fly  1153 LRFKTRGDGYVKIHPSSVNSQVSVF----QAPFLVFQEKVRTSAIYIRDCSMLPLIAMVLFAGSD 1213
                        :||:|     |:|    ...::|:.|.|.|:..|:: |        |.....:
  Rat  1101 ------------LHPTS-----SLFGMGYTPDYIVYHELVMTTKEYMQ-C--------VTAVDGE 1139

  Fly  1214 FKVELHDGDFLFLLESGWIILKAHDLETAEMVQCLRAEMIKLLEEKIR 1261
            :..||  |...:.::......:.:.....|....:..|| .|.||::|
  Rat  1140 WLAEL--GPMFYSVKQAGKSRQENRRRAKEEASAMEEEM-ALAEEQLR 1184

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1582	NP_572663.1	UBA_like_SF	123..154	CDD:473871	4/30 (13%)
		RWD_DHX57	175..367	CDD:467661	43/217 (20%)
		zf-CCCH	245..272	CDD:459885	4/26 (15%)
		HrpA	452..>1075	CDD:441249	198/625 (32%)
		OB_NTP_bind	1114..1212	CDD:400182	21/102 (21%)
Dhx38	NP_001386123.1	PHA03307	<182..>297	CDD:223039	19/132 (14%)
		HrpA	532..>1146	CDD:441249	225/776 (29%)