Protein Alignment CG1582 and Dhx37

DIOPT Version :10

• Sequence 1: NP_572663.1
• Gene: CG1582 / 32021
• FlyBaseID: FBgn0030246
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: NP_001099396.2
• Gene: Dhx37 / 288647
• RGDID: 1306837
• Length: 1150
• Species: Rattus norvegicus
• Alignment Length: 1191
• Identity: 294/1191 - (24%)
• Similarity: 470/1191 - (39%)
• Gaps: 310/1191 - (26%)

  Fly   146 DTEAALLLLYRRYMRIPDEEQLTLEPPSEQEILDMRADEKEALESIFDKAYEEREANRVWNLKFR 210
            |...||:|..|:      :::....|||::|...:...|::.|:.:.::  :|:::.|.
  Rat    43 DASNALVLPGRK------KKKTKAPPPSKKERKPLTKKERKVLQKVLEQ--KEKKSQRA------ 93

  Fly   211 IDHLLAHSPSEVRKAREAVLAAAAAAAQAALDKKKKPPLRCRNFDRDGTCKYGPKCRFAHL---- 271
             :.|...|..:|.:|..::...                          |.|.|...|..|:
  Rat    94 -ELLQKLSEVQVSEAEMSLFYT--------------------------TAKLGTGDRMYHIKERK 131

  Fly   272 PQQPTESDTTKKDSVDENDNELWFHVEVRFPPGSRYPYEAPFIYLKTTCHDIPHELRLRYARHLY 336
            |.||......|..|:                               :..|      |.|:.....
  Rat   132 PDQPAAQGQEKVSSL-------------------------------SGAH------RKRHRSSST 159

  Fly   337 KEAKEICRDGIPCVYSICDLLQSNEQLAG---RLDTSAFPSPKRSLFYDEPAGGGVNPDAEHHQS 398
            :|..|...|..|            |::..   |..|.|      .|.:..||...:.......|.
  Rat   160 EEDSEASEDSEP------------EEVTADQPRTSTGA------DLVHPPPATSEIKSPVPTPQP 206

  Fly   399 PKPSHYARGQTSRNDGGHQRNVEAQTRENRRLLQQFVERRKEERYQKIIDGRKQLPAFAEIERIL 463
            |.|...|..:|..:.........|          .|:...:....|   :.|.:||..||.:.|:
  Rat   207 PPPGTSAPPETPASAPPPALAKPA----------VFIPVNRTPEMQ---EERLKLPILAEEQAIM 258

  Fly   464 ALIESSPVVVISGETGCGKSTQVPQFILDNWFFRALQLPAKENLPHVEIICTQPRRLSAIGVAER 528
            ..:...|:|::.||||.||:||||||:.:..:      .:::::    |..|:|||::|:.:::|
  Rat   259 EAVAEHPIVIVCGETGSGKTTQVPQFLYEAGY------SSEDSI----IGVTEPRRVAAVAMSQR 313

  Fly   529 VAAERLDRIGQLVGYQIRLENKVSQSTRLSFCTTGILLRRLASDPLLGSVTHVIVDEVHERSEES 593
            ||.| ::...::|.||||.|..|::.||:.|.|.|:||:.:..|.||.....||:||.||||..:
  Rat   314 VAKE-MNLSHRVVSYQIRYEGNVTEETRIKFMTDGVLLKEIQKDFLLLKYKVVIIDEAHERSVYT 377

  Fly   594 DFLLLILKNL--LRERK--DLKVILMSATL-------NAALFSDYFGGAPVLDIPGRTFPVQQLF 647
            |.||.:|..:  ||.::  .||:::|||||       |..||:.   ..||:.:..|.|||...|
  Rat   378 DILLGLLSRIVALRAKRHLPLKLLIMSATLRVEDFTQNQRLFTT---PPPVIKVESRQFPVTVHF 439

  Fly   648 LEDILEMSDFVMEYDTKYCRKLK-------------KQEQEILERELEYA-DVQASGEAPGKKIK 698
             .....:.|:..|...|.|:..:             :.|...|.|.|..| .::.|  .|.:..:
  Rat   440 -NKRTPLDDYSGECFRKVCKIHRMLPAGGILVFLTGQAEVHALCRRLRKAFPIRCS--QPQEMEE 501

  Fly   699 DEKLTLAETYQRYAEYSKPTCKSIYLMEPMTINPELIESVLKYIV----EGSHDWPREGTILIFL 759
            |.    ||..:|:.: |:...:....|....||.:      .|.|    ||..|  ||
  Rat   502 DS----AEGMRRFKK-SRTRARKAQAMALPQINLD------NYSVLPAGEGDED--RE------- 546

  Fly   760 PGFGEIQSVHDSL---LDNALFSPRAGK---------FILVPLHSALSGEDQALVFKKAPPGKRK 812
               .|:....::|   ||..|....|.:         ..::||:|.|:.|.||.|||..|.|.|.
  Rat   547 ---AEMDDEEEALGSDLDLDLGDSEANEGEQPDASLPLHVLPLYSLLAPEKQAQVFKPPPEGTRL 608

  Fly   813 IVLSTNIAETSVTIDDCVFVVDCGLMKEKCFDSNRNMESLDLVWVSRANAKQRKGRAGRVMPGVC 877
            .|::||:||||:||....:|||||.:|::.:|....:.|..:.|||:|:|.||.|||||..||.|
  Rat   609 CVIATNVAETSLTIPGIKYVVDCGKVKKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHC 673

  Fly   878 IHLYTSYRY----QYHILAQPVPEIQRVPLEQIVLRIKTL----------------QTFASRNTL 922
            ..||:|..:    |:     |.|||.|.|:|.::|::|.|                :...:...|
  Rat   674 YRLYSSAVFGDFEQF-----PPPEITRRPVEDLILQMKALNIEKVINFPFPTPPSVEALIAAEEL 733

  Fly   923 SVLLETLEAPTEDSVLGALTRLRDVGALDAEDQLTPLGHHLAALPVDVRIGKLMLYGAIFQCLDS 987
            .:.|..|:||.:..      |::.:........:|.||..::..||..|..|::.......||..
  Rat   734 LIALGALQAPPKQE------RMKKLQMSQLSCPITALGRTMSTFPVAPRYAKMLALSQQHGCLPY 792

  Fly   988 VLTIAACLSNKSPF------------VSPL-NKRTEADKCKRMFA-----LGNSDHLTVLNAYRK 1034
            .:.|.|.::.:..|            ::.| .:||...:.||.:|     |...|.:.:|.|
  Rat   793 TIAIVAAMTVRELFEELDRPAASEEELAELKGRRTRVAQMKRTWAGQGASLKLGDLMVLLGA--- 854

  Fly  1035 WLDVARRGNYAASRNYA--SEHFLSLNTLETIADLKYQYL--ELLVSIGFVPIDVPRRRKNACDN 1095
                      ..:..||  |..|...|.|...|.|:.:.|  :|..::..|           |..
  Rat   855 ----------VGACEYAGCSPQFCQANGLRYKAMLEIRRLRGQLTTAVNAV-----------CPE 898

  Fly  1096 I-LTLTGVEQNHNGDNNRLLTSLLCAALYPNIVKIMTPDRVYIQTAGGAVPREPSHHDL------ 1153
            . |.|....|.........|..::.|.|                  |..:.|.....||
  Rat   899 AGLFLDPKMQPPTESQVTYLRQIMAAGL------------------GDHLARRVQSEDLLDPKWK 945

  Fly  1154 -RFKT-RGDGYVKIHPSSVNSQVSVFQ--APFLVFQEKVRTSAIYIRDCSMLPL--IAMVLFAGS 1212
             .:|| ..|..|.||||||     :|:  ..|:|:||.|.|:.:|::..|.:.:  |..:|.:..
  Rat   946 NAYKTPLLDDPVFIHPSSV-----LFRELPEFVVYQEIVETTKMYMKGVSTVEIQWIPSLLPSYC 1005

  Fly  1213 DFKVELHDGDFLFLLESGWII 1233
            .|...|.:....:..|||.::
  Rat  1006 QFDAPLEEPAPTYCPESGRVL 1026

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1582	NP_572663.1	UBA_like_SF	123..154	CDD:473871	3/7 (43%)
		RWD_DHX57	175..367	CDD:467661	27/198 (14%)
		zf-CCCH	245..272	CDD:459885	5/30 (17%)
		HrpA	452..>1075	CDD:441249	205/705 (29%)
		OB_NTP_bind	1114..1212	CDD:400182	28/109 (26%)
Dhx37	NP_001099396.2	HrpA	248..>1036	CDD:441249	244/877 (28%)