Protein Alignment CG1582 and gih35

DIOPT Version :10

• Sequence 1: NP_572663.1
• Gene: CG1582 / 32021
• FlyBaseID: FBgn0030246
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: NP_593629.1
• Gene: gih35 / 2542874
• PomBaseID: SPAC20H4.09
• Length: 647
• Species: Schizosaccharomyces pombe
• Alignment Length: 765
• Identity: 208/765 - (27%)
• Similarity: 338/765 - (44%)
• Gaps: 165/765 - (21%)

  Fly   450 RKQLPAFAEIERILALIESSPVVVISGETGCGKSTQVPQFILD-NWFFRALQLPAKENLPHVEII 513
            :|.||......::|..:|.:.:.::.|.|||||:||:|||:.: .|        |.:|    .||
pombe    22 KKLLPITKYRNQLLYAVEQNQITIVLGHTGCGKTTQIPQFLYEAGW--------ASQN----GII 74

  Fly   514 -CTQPRRLSAIGVAERVAAERLDRIGQLVGYQIRLENKVSQSTRLSFCTTGILLRRLASDPLLGS 577
             |||||||.|..|:|||:.|.....|.|.||.|:.::.||:.|::.:.|.||||..:..||||..
pombe    75 GCTQPRRLVAKSVSERVSLELNSPPGSLCGYSIQFDHNVSEKTKIKYMTDGILLNEIFFDPLLER 139

  Fly   578 VTHVIVDEVHERSEESDFLLLILKNLLRERKDLKVILMSATLNAALFSDYFGGAPV--LDIPGRT 640
            .:.||:||||||:..:|.||.:||.:|.:|.|.:::|.||:::|...|.:||...|  :.|.|:.
pombe   140 YSIVILDEVHERTLSTDLLLGVLKRILEKRNDFRLVLSSASVDANKLSQFFGQDKVCTMSIEGKL 204

  Fly   641 FPVQQLFLEDILEMSDFVMEYDTKYCRKLKKQEQEILERELEYADVQASGEAPGKKIKDEKLTLA 705
            |||:.|||:
pombe   205 FPVETLFLQ-------------------------------------------------------- 213

  Fly   706 ETYQRYAEYSKPTCKSIYLMEPMTINPELIESVLKYIVEGSHDWPREGTILIFLPGFGEIQ---- 766
                      |||             ...::|.::.::..:..:| .|.||:||.|..||:
pombe   214 ----------KPT-------------ENYVDSAIETVININSTYP-PGDILVFLSGRKEIEYCIK 254

  Fly   767 SVHDSLLDNALFSPRAGKFILVPLHSALSGEDQALVFKKAPPGKRKIVLSTNIAETSVTIDDCVF 831
            .:.|||:.   .|......:.:|||:.|:.::|..||.......||::.||||||||:|||..|:
pombe   255 KIEDSLIH---ASEDCQTLVPLPLHAGLTVDEQMRVFNIYDGDFRKVIFSTNIAETSITIDGIVY 316

  Fly   832 VVDCGLMKEKCFDSNRNMESLDLVWVSRANAKQRKGRAGRVMPGVCIHLYTSYRYQYHILAQPVP 896
            |||.|..|::.::.......|..|.:|:::|.||.|||||.|.|....|||...|.. :..:...
pombe   317 VVDSGFNKQRIYNPYTRTSKLINVPISKSSAIQRSGRAGRTMRGKVFRLYTEKAYSL-MKEEFEA 380

  Fly   897 EIQRVPLEQIVLRIKTLQTFASRNTLSVLLETLEAPTEDSVLGALTRLRDVGALDAEDQLT-PLG 960
            :|....:..:||.:|.|   ..:|.|.  ......|....::.||..|..:|.||....|| |||
pombe   381 DILNCDMSPLVLFLKGL---GLKNILQ--FPFFVRPPTVHLMAALEDLYLLGVLDESGNLTDPLG 440

  Fly   961 HHLAALPVDVRIGKLMLYGAIFQCLDSVLTIAACLSNKSPFVSPL-NKRTEADKCKRMFALGNSD 1024
            ..::...:|..|.|.:|....|.|...:|:||:.|:....|.:|. :.:.:|......|.....|
pombe   441 IQISNSFLDANISKALLTSNQFGCTHEILSIASILTAGEVFYNPTSSSKNDAFVAHSSFFANEGD 505

  Fly  1025 HLTVLNAYRKWLDVARRGNYAASRNYASEHFLSLNTLETIADLKYQYLELLVSIGFVPIDVPRRR 1089
            .:|.||.:..::     || .....:..:::|:..||....|::...:..|
pombe   506 IITALNVFESFV-----GN-KKDLQWCRKNYLNYQTLRQALDIRTHLVRFL-------------- 550

  Fly  1090 KNACDNILTLTGVEQNHNGDNNRLLTSLLCAALYPNIVKIMTPDRVYIQTAGGAVPREPSH--HD 1152
                 |..::...::..:.|.:::|..||                      .|.| |..:|  :|
pombe   551 -----NKFSIPTAQRLPSSDCSKILKCLL----------------------DGFV-RNVAHLQND 587

  Fly  1153 LRFKTRGDGYVKIHPSSVNSQVSVFQAPFLVFQEKVRT-SAIYIRDCSML 1201
            ..:||.|...|.:..|||..:.   :.|::::...|.: :.|::::.|.:
pombe   588 GSYKTIGGKQVWLDSSSVLHEK---KTPWIMYSSAVESETQIFVKNISKI 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1582	NP_572663.1	UBA_like_SF	123..154	CDD:473871
		RWD_DHX57	175..367	CDD:467661
		zf-CCCH	245..272	CDD:459885
		HrpA	452..>1075	CDD:441249	185/632 (29%)
		OB_NTP_bind	1114..1212	CDD:400182	19/91 (21%)
gih35	NP_593629.1	HrpA	25..>627	CDD:441249	205/753 (27%)