Protein Alignment CG1582 and cdc28

DIOPT Version :10

• Sequence 1: NP_572663.1
• Gene: CG1582 / 32021
• FlyBaseID: FBgn0030246
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: NP_595686.2
• Gene: cdc28 / 2540707
• PomBaseID: SPBC19C2.01
• Length: 1055
• Species: Schizosaccharomyces pombe
• Alignment Length: 1235
• Identity: 323/1235 - (26%)
• Similarity: 498/1235 - (40%)
• Gaps: 334/1235 - (27%)

  Fly     4 SSRKHMEDCFLR-----SPSDI----RTTNVPAAPKSQAADNKSRKTELHVLRLNDESRQMTMDT 59
            ::||..|...|:     |..|:    ::...|..|..:.:.:|:.|.|: ..|..||.
pombe    78 NARKKKEQGILQMERLNSSYDLLIEPQSHETPGKPLKKKSRSKTPKREI-ARRQRDED------- 134

  Fly    60 LRQIHGPEFQLDDISKYKDRGRGGHGVK----------HSYWQDRGTLVVQSVQGVSSTRGNDSD 114
                   |::.|:..:..| |...|.::          |.|.:...    ...:.::..|..:..
pombe   135 -------EWESDEYEEVVD-GSASHPIEEDSVSTDFQNHDYEKSSD----PETERLNDLREREEF 187

  Fly   115 GDRLRRYALAKLENYGFQAVHCLEAYEHCSGDTEAALLLLYRRYMRIPDEEQLTLEPPSEQEILD 179
            .:||||                        .|.|||.......|......|:|.|.
pombe   188 EERLRR------------------------KDLEAATNEFVEDYSSKFSSEELALR--------- 219

  Fly   180 MRADEKEALESIFDKAYEEREANRVWNLKFRIDHLLAHSPSEVRKAREAVLAAAAAAAQAALD-- 242
            ..||:.|:...:   |.|.|:.:|...||.|....|.....|:|.  |..|.|.....||.:.
pombe   220 KLADDPESWRKL---ASELRKKSRQQYLKPRAQQQLEILRREIRD--EEQLFAGEKLTQAEIREL 279

  Fly   243 KKKKPPLRC----RNFDRDGTCKYGPKCRFAHLPQQPTESDTTKKDSVDENDNELWFHVEVRFPP 303
            :|||..||.    :..::..| :|          |.| |...|::..:|....|
pombe   280 EKKKELLRIAEERQRLEKQAT-EY----------QMP-EDYFTEQGKLDRKRKE----------- 321

  Fly   304 GSRYPYEAPFIYLKTTCHDIPHELRLRYARHLYKEAKEICRDGIPCVYSICDLLQSNEQLAGRLD 368
                                    .:.|.|  ||::.|    |           :.||...|..:
pombe   322 ------------------------EVLYQR--YKDSNE----G-----------EQNEVTMGAAE 345

  Fly   369 TSAFPSPK--RSLFYDE----PAGGGVNPDAEHHQSPKPSHYARGQTSRNDGGHQRNVEAQTR-E 426
            ...:.:.:  ::|.:|:    |.|            .|...:...::.:.|......:.|:.. :
pombe   346 QQRWEAQQINKALLFDQNEWLPPG------------EKQFDFVFDESQQIDFLLDTKLSAENPVD 398

  Fly   427 NRRLLQQFVERRKEERYQKIIDGRKQLPAFAEIERILALIESSPVVVISGETGCGKSTQVPQFIL 491
            ..::....||:..|       ..||.||.:...:.:|..|....|::|..|||.||:||:|||:.
pombe   399 TDKMTDVKVEKSLE-------SSRKSLPVYQYKDDLLKAINEYQVLLIVAETGSGKTTQLPQFLH 456

  Fly   492 DNWFFRALQLPAKENLPHVEIICTQPRRLSAIGVAERVAAERLDRIGQLVGYQIRLENKVSQSTR 556
            :..:.:.          :.:|.||||||::|:.||.|||.|...|:||.|||.||.||..|:.|.
pombe   457 EAGYTKG----------NKKICCTQPRRVAAMSVAARVAKEMDVRLGQEVGYSIRFENATSEKTV 511

  Fly   557 LSFCTTGILLRRLASDPLLGSVTHVIVDEVHERSEESDFLLLILKNLLRERKDLKVILMSATLNA 621
            :.:.|.|:|||...::|.|.|.:.:|:||.|||:..:|.|..::|::.|.|.||||::.|||::|
pombe   512 IKYLTDGMLLREFLTEPDLASYSVIIIDEAHERTLHTDILFGLVKDIARFRPDLKVLISSATIDA 576

  Fly   622 ALFSDYFGGAPVLDIPGRTFPVQQLFLEDILEMSDFVMEYDTKYCRKLKKQEQEILERELEYADV 686
            ..||.||..|||..:|||.:||      ||
pombe   577 EKFSAYFDEAPVFYVPGRRYPV------DI----------------------------------- 600

  Fly   687 QASGEAPGKKIKDEKLTLAETYQRYAEYSKPTCKSIYLMEPMTINPELIESVLKYIVEGSHDWPR 751
                                       |..|..::.|:...:|       ::|:.     |....
pombe   601 ---------------------------YYTPQPEANYIQAAIT-------TILQI-----HTTQP 626

  Fly   752 EGTILIFLPGFGEIQSVHDSLLDNA-LFSPRAGKFILVPLHSALSGEDQALVFKKAPPGKRKIVL 815
            .|.||:||.|..||:.:.:::.:.. :...|..:.||.|:::.|..|.||.:|...|||.||:||
pombe   627 AGDILVFLTGQDEIELMSENMQELCRILGKRIPEIILCPIYANLPSELQAKIFDPTPPGARKVVL 691

  Fly   816 STNIAETSVTIDDCVFVVDCGLMKEKCFDSNRNMESLDLVWVSRANAKQRKGRAGRVMPGVCIHL 880
            :|||||||:|||...||:|.|.:|:..::....||||..|..|||:|.||.||||||.||.|..|
pombe   692 ATNIAETSITIDGVNFVIDSGFVKQNMYNPRTGMESLVSVPCSRASADQRAGRAGRVGPGKCFRL 756

  Fly   881 YTSYRYQYHILAQPVPEIQRVPLEQIVLRIKTLQTFASRNTLSVLLETLEAPTEDSVLGALTRLR 945
            ||...|...:.....|||||..|..|||.:|:|   ...|.|.  .:.::||..::::.:|..|.
pombe   757 YTRRTYNNELDMVTSPEIQRTNLTNIVLLLKSL---GINNLLD--FDFMDAPPPETLMRSLELLY 816

  Fly   946 DVGALDAEDQLTPLGHHLAALPVDVRIGKLMLYGAIFQCLDSVLTIAACLSNKSP-FVSPLNKRT 1009
            .:|||:...:||.||..:|..|.|..:.|.::..:.:.|::.||:|.:.|...|. |..|.:|..
pombe   817 ALGALNNRGELTKLGRQMAEFPTDPMLSKSLIASSKYGCVEEVLSIVSMLGEASSLFYRPKDKIM 881

  Fly  1010 EADKCKRMFALGNSDHLTVLNAYRKWLDVARRGNYAASRNYASEHFLSLNTLETIADLKYQYLEL 1074
            ||||.:..|.....||||:|:.:.:|:|.      ..|.|:|.|:||...:|....|::.|.
pombe   882 EADKARANFTQPGGDHLTLLHIWNEWVDT------DFSYNWARENFLQYKSLCRARDVRDQL--- 937

  Fly  1075 LVSIGFVPIDVPRRRKNACDNILTLTGVEQNHNGDNNRLLTSLLCAALYPNIVKIMTPDRVYIQT 1139
                           .|.|:.:    .:|...|...          :|.| |.|.:|..  |...
pombe   938 ---------------ANLCERV----EIELVTNSSE----------SLDP-IKKAITAG--YFSN 970

  Fly  1140 AGGAVPREPSHHDLRFKTRGDGY--------VKIHPSSVNSQVSVFQAPFLVFQEKVRTSAIYIR 1196
            |.            |....||.|        |.||||   |.|:..:...:::.|.|.|:..|.|
pombe   971 AA------------RLDRSGDSYRTVKSNQTVYIHPS---SSVAEKKPKVIIYFELVLTTKEYCR 1020

  Fly  1197  1196
            pombe  1021  1020

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1582	NP_572663.1	UBA_like_SF	123..154	CDD:473871	4/30 (13%)
		RWD_DHX57	175..367	CDD:467661	40/197 (20%)
		zf-CCCH	245..272	CDD:459885	6/30 (20%)
		HrpA	452..>1075	CDD:441249	210/624 (34%)
		OB_NTP_bind	1114..1212	CDD:400182	23/91 (25%)
cdc28	NP_595686.2	PTZ00121	<68..>357	CDD:173412	74/400 (19%)
		DUF4670	<213..322	CDD:464815	34/169 (20%)
		HrpA	417..>1039	CDD:441249	237/755 (31%)