Protein Alignment CG1582 and prp16

DIOPT Version :10

• Sequence 1: NP_572663.1
• Gene: CG1582 / 32021
• FlyBaseID: FBgn0030246
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: NP_595890.2
• Gene: prp16 / 2540006
• PomBaseID: SPBC1711.17
• Length: 1173
• Species: Schizosaccharomyces pombe
• Alignment Length: 1272
• Identity: 318/1272 - (25%)
• Similarity: 521/1272 - (40%)
• Gaps: 287/1272 - (22%)

  Fly    34 ADNKSRKTE----LHVL-RLNDESRQMTMDTLRQIHGPEFQLDDISKYKDRGRGGHGVKHSYWQD 93
            |...|..||    ||.. |.:|....:..|..:.|.|.|..| .|||.|..|..|..|......:
pombe    39 AKGSSSSTEFSNALHTFGRFSDNDSVLIYDLCKSIIGLETNL-GISKDKLPGNDGSQVAGLVLSN 102

  Fly    94 RG---------------TLVVQSVQGVSSTRGNDSDGDRLRRYALAKLENYGFQAVHCLEAYEHC 143
            |.               .|.||..:..|...|         |..|:::||...:::...:..|
pombe   103 RSGLKGREPKKSQLGLDVLAVQKKKEKSQVEG---------RSELSQVENDSLESIGNYDRVE-- 156

  Fly   144 SGDTEAALLLLYRRYMRIPDEEQLTLEPPSEQEILDMR----ADEKEALESIFDKAYEEREANRV 204
                       ::|    |       :.|.|:....:|    .|:.:..||..||  ..|.:...
pombe   157 -----------FKR----P-------KNPHEKHFRPLRQRSSVDDHQEFESEDDK--YRRNSYSS 197

  Fly   205 WNLKFRIDHLLAHSPSEVRKAREAVLAAAAAAAQAALDKKKKPPLRCRNFDRDGTCKYGP----K 265
            |:    ..:..:.:.|..|:.|..:....::..:.......:..:....:..|....||.    .
pombe   198 WS----GSNFESSNGSNRRRYRTQMEEPLSSKRRNRFGNGSRRDVDSSKYSHDSDYSYGAHSSWD 258

  Fly   266 CRFAHLPQQPTESDTTKKDSVDEN---DNELWFHVEVRFPPGSRYPYEAPFIYLKTTCHDIPHEL 327
            .|....|::..||...::...:|.   |.:.:.:.|.:...|..  ...||...:|. .|..||.
pombe   259 ARDVEYPEEDPESKADRQRWEEEQAHLDRDWYMNSESQNLLGDE--VHNPFSDFETV-EDRAHEA 320

  Fly   328 RL--RYARHLYKEAKEICRD------------------GIPCVYSICD----LLQSNEQLAGRLD 368
            ..  :..:||..||.:..::                  |:...||:.:    .|..:|.....||
pombe   321 EFIEKQKKHLSIEASDRFKENSMWEKNRMITSGVSKAPGLESDYSLMEERRVHLLVDELRPHFLD 385

  Fly   369 TSAFPS-----------PKRSLFYDEPAGGG-VNPDAEHHQSPKPSHYA-----------RGQTS 410
            .:.|.|           |:..|..:...|.. |....|..:..|.:..|           .|...
pombe   386 GAEFSSKKVGDITSVRDPQSDLAINARLGSRLVRERREFRERQKAASAATSLAGTSLGNVMGLKD 450

  Fly   411 RND-----GGHQRNVEAQTRENRRLLQQFVERRKEERYQKIIDGRKQLPAFAEIERILALIESSP 470
            .||     |.....|..::.::.:...:|. |.|..|.|     |:.|||||..|::|::|..:.
pombe   451 SNDEDAKAGTTPVKVAGRSEQSNKKDTEFA-RTKSYREQ-----REFLPAFAVREQLLSVIRDNQ 509

  Fly   471 VVVISGETGCGKSTQVPQFILDNWFFRALQLPAKENLPHVEIICTQPRRLSAIGVAERVAAERLD 535
            |:::.||||.||:||:.||:.::.:.|           :..|.||||||::|:.||:||:.|...
pombe   510 VLIVVGETGSGKTTQLAQFLYEDGYHR-----------NGMIGCTQPRRVAAMSVAKRVSEEMGV 563

  Fly   536 RIGQLVGYQIRLENKVSQSTRLSFCTTGILLRRLASDPLLGSVTHVIVDEVHERSEESDFLLLIL 600
            |:|..|||.||.|:.....|.:.:.|.|:|||.......|...:.:|:||.||||..:|.|:.:|
pombe   564 RLGSTVGYSIRFEDVTGPDTVIKYMTDGVLLRESLMQNNLEKYSVIIMDEAHERSLNTDILMGLL 628

  Fly   601 KNLLRERKDLKVILMSATLNAALFSDYFGGAPVLDIPGRTFPVQQLFLEDILEMSDFVMEYDTKY 665
            |.:|..|:|:|:::.|||:|:..|||:|||||...|||||:||..:|.:  ...||:|
pombe   629 KKVLSRRRDIKLLVTSATMNSQKFSDFFGGAPQFTIPGRTYPVDIMFAK--APCSDYV------- 684

  Fly   666 CRKLKKQEQEILERELEYADVQASGEAPGKKIKDEKLTLAETYQRYAEYSKPTCKSIYLMEPMTI 730
                                     ||..:::                      ..|:|.:|
pombe   685 -------------------------EAAVRQV----------------------LQIHLSQP--- 699

  Fly   731 NPELIESVLKYIVEGSHDWPREGTILIFLPGFGEIQSVHDSLLDNALFSPRAGKFILVPLHSALS 795
                                 .|.||:|:.|..:|::..:.:.|.......|.:..::|::|.:.
pombe   700 ---------------------AGDILVFMTGQEDIEATCEIIADRLNQLHDAPRLSILPIYSQMP 743

  Fly   796 GEDQALVFKKAPPGKRKIVLSTNIAETSVTIDDCVFVVDCGLMKEKCFDSNRNMESLDLVWVSRA 860
            .:.||.:|..|.||.||:|::|||||||:|:....:|||.|..|.|.::|...:::|.:..:|:|
pombe   744 ADLQAKIFDSAEPGVRKVVVATNIAETSLTVHGISYVVDTGYCKLKMYNSKLGIDTLQVTPISQA 808

  Fly   861 NAKQRKGRAGRVMPGVCIHLYTSYRYQYHILAQPVPEIQRVPLEQIVLRIKTLQTFASRNTLSVL 925
            ||.||.|||||..||:...|||...|...:....:|||||..|...||.:|:|......:
pombe   809 NANQRAGRAGRTGPGIAYRLYTEMAYIREMFETTLPEIQRTNLSNTVLILKSLGVEEISD----- 868

  Fly   926 LETLEAPTEDSVLGALTRLRDVGALDAEDQLTPLGHHLAALPVDVRIGKLMLYGAIFQCLDSVLT 990
            .:.::.|..|:::.:|..|..:||||...:||.||..::..|:|..:.||::....::|.:.::|
pombe   869 FDFMDRPPNDTLMASLYELWTLGALDNFGKLTTLGKKMSLFPMDPSLSKLIIIAEDYKCTEEIIT 933

  Fly   991 IAACLSNKSPFVSPLNKRTEADKCKRMFALGNSDHLTVLNAYRKWLDVARRGNYAASRNYASEHF 1055
            |.:.||..|.|..|..:..|:|..:..|.:..||||.:||.|:.|    :|..|  |.::.|:||
pombe   934 IVSMLSVPSVFYRPKERAEESDAAREKFNVPESDHLMLLNIYQHW----QRNGY--SNSWCSKHF 992

  Fly  1056 LSLNTLETIADLKYQYLELL----VSIGFV-PIDVPRRRKNACDNILTLTGVEQNHNGDNNRLLT 1115
            |...||:...|::.|.:|::    :|:..| ..|:.||
pombe   993 LHSKTLKRARDIRQQLVEIMSKQKISLESVSDWDIVRR--------------------------- 1030

  Fly  1116 SLLCAALYPNIVKIMTPDRVYIQTAGGAVPREPSHHDLRFKTRGDGYVKIHPSSVNSQVSVFQAP 1180
             :||:| |.:..........|:....|.    |.|..:.....|.||:               ..
pombe  1031 -VLCSA-YFHQAACAKGIGEYVHLRSGM----PCHLHVTSSLYGLGYL---------------PD 1074

  Fly  1181 FLVFQEKVRTSAIYIRDCSMLPLIAMVLFAGSDFKVE 1217
            ::::.|.|.||..|:...:.:....:..|.|..:.|:
pombe  1075 YVIYHELVLTSKEYMNIVTSVDPYWLAEFGGVYYSVK 1111

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1582	NP_572663.1	UBA_like_SF	123..154	CDD:473871	4/30 (13%)
		RWD_DHX57	175..367	CDD:467661	37/226 (16%)
		zf-CCCH	245..272	CDD:459885	4/30 (13%)
		HrpA	452..>1075	CDD:441249	200/622 (32%)
		OB_NTP_bind	1114..1212	CDD:400182	17/97 (18%)
prp16	NP_595890.2	HrpA	492..>1087	CDD:441249	220/744 (30%)