Protein Alignment CG1582 and DHX30

DIOPT Version :10

• Sequence 1: NP_572663.1
• Gene: CG1582 / 32021
• FlyBaseID: FBgn0030246
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: XP_047303683.1
• Gene: DHX30 / 22907
• HGNCID: 16716
• Length: 1265
• Species: Homo sapiens
• Alignment Length: 875
• Identity: 295/875 - (33%)
• Similarity: 443/875 - (50%)
• Gaps: 136/875 - (15%)

  Fly   426 ENRRLLQQFVE--RRKEERYQKIIDGRKQLPAFAEIERILALIESSPVVVISGETGCGKSTQVPQ 488
            |..||.|..:|  ||:...:|:    ..|||.....:.||..||..|||||||:|||||:|::||
Human   480 EEVRLSQSLLELWRRRGPVWQE----APQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQ 540

  Fly   489 FILDNWFFRALQLPAKENLPHVEIICTQPRRLSAIGVAERVAAERLDRIGQLVGYQIRLENK-VS 552
            .:|:.:.       .:.......:|.|||||:||:.||:||:.|....:.:.||:|:|||:| .|
Human   541 LLLERYV-------TEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPS 598

  Fly   553 QSTRLSFCTTGILLRRLASDPLLGSVTHVIVDEVHERSEESDFLLLILKNLLRERKDLKVILMSA 617
            :...|.|||.|||||:|.|:|.|..|:||||||||||...:||||::||.|.|....|:::||||
Human   599 RGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSA 663

  Fly   618 TLNAALFSDYFGGAPVLDIPGRTFPVQQLFLEDILEMSDFVMEYDTKYCRKLKKQEQEILERELE 682
            |.:...||.||||.||:.:||..:||::.:|||||              .||.|  .:.|.|
Human   664 TGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDIL--------------AKLGK--HQYLHR--- 709

  Fly   683 YADVQASGEAPGKKIKDEKLTLAETYQRYAEYSKPTCKSIYLMEPMTINPELIESVLKYI-VEGS 746
                                      .|:.| |:..|         .::.:|:..::.:| ..|
Human   710 --------------------------HRHHE-SEDEC---------ALDLDLVTDLVLHIDARG- 737

  Fly   747 HDWPREGTILIFLPGFGEIQSVHDSLLDNALFSPRAGKFILVPLHSALSGEDQALVFKKAPPGKR 811
                ..|.||.||||:.||:.|...|.:  .......|::::|:||.:...||..:|::.|.|.|
Human   738 ----EPGGILCFLPGWQEIKGVQQRLQE--ALGMHESKYLILPVHSNIPMMDQKAIFQQPPVGVR 796

  Fly   812 KIVLSTNIAETSVTIDDCVFVVDCGLMKEKCFDSNRNMESLDLVWVSRANAKQRKGRAGRVMPGV 876
            ||||:|||||||:||:|.|.|||.||.||:.:|....:..|:.|||||||..||:|||||...|.
Human   797 KIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGF 861

  Fly   877 CIHLYTSYRYQYHILAQPVPEIQRVPLEQIVLRIKTLQTFASRNTLSVLLETLEAPTEDSVLGAL 941
            ..||:...|.:..:..| ||||.|.|||.:||:.|.  ....:..:..|.:.:::|...:|..|:
Human   862 AYHLFPRSRLEKMVPFQ-VPEILRTPLENLVLQAKI--HMPEKTAVEFLSKAVDSPNIKAVDEAV 923

  Fly   942 TRLRDVGALDAEDQLTPLGHHLAALPVDVRIGKLMLYGAIFQCLDSVLTIAACLSNKSPFVSPLN 1006
            ..|:::|.||..:.||.||..||.:..|.|:.|.::..|||:||..:|.:.:||: :.||.|.|.
Human   924 ILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT-RDPFSSSLQ 987

  Fly  1007 KRTEADKCKRMFAL-GNSDHLTVLNAYRKWLDVARRGNYAASRNYASEHFLSLNTLETIADLKYQ 1070
            .|.|.||.|.:.:. ..||||..:.|...|.:|.|..:.::..||..|:.|...:|..|..|..|
Human   988 NRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQ 1052

  Fly  1071 YLELLVSIGFV--PIDVPRRRKNACDNILTLTGVEQNHNGDNNRLLTSLLCAALYPNIVKIMTPD 1133
            :.|.:.....|  |.|        |    ||...:.|...:...|:..:|.|.||||:
Human  1053 FSENIYEAFLVGKPSD--------C----TLASAQCNEYSEEEELVKGVLMAGLYPNL------- 1098

  Fly  1134 RVYIQTAGGAVPREPSH--HDLRFKTRGDGYVKIHPSSVNSQVSVFQAPFLVFQEKVRTS-AIYI 1195
               ||...|.|.|:...  :.:.::|: .|.:.:|.|::|.:.:..::.:|.:...|::: ::::
Human  1099 ---IQVRQGKVTRQGKFKPNSVTYRTK-SGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFV 1159

  Fly  1196 RDCSMLPLIAMVLFAGSDF---------KVELHDGDFLFLLESGWIILKAHDLETA--EMVQ-CL 1248
            ||.|.:..:|::|....|.         .:.|.|.|.|.|......:....:|..|  .||: .|
Human  1160 RDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLKELRRALGRMVERSL 1224

  Fly  1249 RAE--------------MIKLLEEKIRDPC 1264
            |:|              ::.||.|.:|.||
Human  1225 RSELAALPPSVQEEHGQLLALLAELLRGPC 1254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1582	NP_572663.1	UBA_like_SF	123..154	CDD:473871
		RWD_DHX57	175..367	CDD:467661
		zf-CCCH	245..272	CDD:459885
		HrpA	452..>1075	CDD:441249	237/625 (38%)
		OB_NTP_bind	1114..1212	CDD:400182	23/100 (23%)
DHX30	XP_047303683.1	HrpA	497..>1029	CDD:441249	229/608 (38%)
		OB_NTP_bind	1086..1173	CDD:400182	22/97 (23%)