Protein Alignment CG1582 and rha-2

DIOPT Version :10

• Sequence 1: NP_572663.1
• Gene: CG1582 / 32021
• FlyBaseID: FBgn0030246
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: NP_498895.1
• Gene: rha-2 / 176207
• WormBaseID: WBGene00015525
• Length: 1148
• Species: Caenorhabditis elegans
• Alignment Length: 1102
• Identity: 275/1102 - (24%)
• Similarity: 442/1102 - (40%)
• Gaps: 246/1102 - (22%)

  Fly   193 DKAYEEREANRVWNLKFRIDHLLAHSPSEVRKAREAVLAAAAAAAQAALDKKKKPPLRCRNFDRD 257
            |.|.|:.:||.           |...|.|.||..|      .:..::|...||.     |||.::
 Worm     9 DNASEDYDANE-----------LMIVPGEKRKKLE------KSGEKSATGGKKN-----RNFAKE 51

  Fly   258 GTCKYGPKCRFAHLPQQPTE--SDTTKKDSVDENDNELWFHV-EVRFPPG-----------SRYP 308
            .        ..|.|.:|...  :....:.::.:...||:..: |.:..|.           |:.|
 Worm    52 K--------EVAKLTKQAKRKLAAVQSRKALKQTQEELFAGLAEFQLDPSKLCQLSSSTKLSKEP 108

  Fly   309 YEAPFIYLKTTCHDIPHELRLRYARHLYKEAKEICRDGIPCVYSICDLLQSNEQ----------- 362
            .:||.         .|.:|:: ::.....|||...:|    .|...|...|.|:
 Worm   109 EKAPV---------FPEKLKV-FSGKTKTEAKRTQQD----YYPTDDESSSEEEEEEEEGDNDIE 159

  Fly   363 -LAGRLDTSAFPSPKRSLFYDEPAGGGVNPDAEHHQSPKPSHYARGQTSRNDGGHQRN-----VE 421
             ....::....|.....:  ||...|  ||:....|.         ...|.|.....|     :.
 Worm   160 DAGNTVEVKIEPIDLDDV--DEAIDG--NPETNLDQI---------VVKREDDEESDNEDILALP 211

  Fly   422 AQTRENRRLLQQFVERRKEERYQKIIDGRKQLPAFAEIERILALIESSPVVVISGETGCGKSTQV 486
            ..|..||:  :..|||.||     |...|.:||.|||..||:..|..:.|.|:.||||.||:||:
 Worm   212 TTTVINRK--KVIVERSKE-----IQKSRAELPIFAEEMRIVEAINENLVTVVCGETGSGKTTQI 269

  Fly   487 PQFILDNWFFRALQLPAKENLPHVEII-CTQPRRLSAIGVAERVAAE--RLDRIGQLVGYQIRLE 548
            |||:.:..:       |.|.    |:| .|:|||::||.:|:||..|  :.|.    |.||||.|
 Worm   270 PQFLYEAGY-------ASEG----ELIGITEPRRVAAIAMAQRVGVELAKPDE----VSYQIRYE 319

  Fly   549 NKVSQSTRLSFCTTGILLRRLASDPLLGSVTHVIVDEVHERSEESDFLLLILKNL--LRER--KD 609
            ...|::|.:.|.|.|:|::.:..|.:|...:.:::||.||||..||.|:.:|..:  ||.:  :.
 Worm   320 GTRSETTNILFMTDGVLMKEMEQDVMLKKYSVILIDEAHERSMYSDVLIGMLSRIVPLRSKTARP 384

  Fly   610 LKVILMSATL------NAALFSDYFGGAP-----VLDIPGRTFPVQQLFLEDILEMSDFVMEYDT 663
            |::::|||||      :..||       |     |:.:..|.|||...|  :.....|::.....
 Worm   385 LRLVIMSATLRLDDFTHKKLF-------PLLTPKVIKVDARQFPVSVHF--EKRTPDDYIASAFR 440

  Fly   664 KYCR-------------------------KLKKQEQEILERELEYADVQASGEAPGKKIKDEKLT 703
            |.||                         ||||:...:.|.: :..:|...|.   |:.|::|:.
 Worm   441 KTCRIHETLPPGAILVFVTGQHEVKQLITKLKKRYPVVYETD-KNGEVLVKGT---KEWKEKKVE 501

  Fly   704 LAETYQRYAEYSKPTCKSIYLMEPMTINPEL--IESVLKYIVEGSHDWPREGTILIFLPGFGEIQ 766
            .|              |||.|.:.....||.  .|.|...:::|. |....|....| ..:.|.:
 Worm   502 AA--------------KSIKLEDFKEETPETEDFEDVDDGLMDGD-DMNERGAAEAF-DDYEEFE 550

  Fly   767 S----VHDSLLDNALFSPRAG--KFILVPLHSALSGEDQALVFKKAPPGKRKIVLSTNIAETSVT 825
            :    :.|..::|::.:|.|.  ....:||:|.||...|..||.:.|.|.|..|:|||:||||:|
 Worm   551 NGDGDLSDGKVENSIGAPPADCEPLYCLPLYSLLSMGKQRRVFDETPAGMRLCVISTNVAETSLT 615

  Fly   826 IDDCVFVVDCGLMKEKCFDSNRNMESLDLVWVSRANAKQRKGRAGRVMPGVCIHLYTSYRYQYHI 890
            |....:|:|.|..|.:.:||...:....:..:|:|:..||.|||||:..|....||:|..||..:
 Worm   616 IPGVKYVIDGGFEKRRLYDSITGVSRFAVCRISQASGDQRAGRAGRISAGHAYRLYSSAVYQDFV 680

  Fly   891 LAQPVPEIQRVPLEQIVLRIKTLQTFASRNTLSVL-LETLEAPTEDSVLGALTRLRDVGALD--- 951
            .... |||...|.:|:||.:|      |.|.:.|: .....||.|..:..|..||..:|||.
 Worm   681 KFAD-PEILSKPADQLVLHLK------SMNIVKVVNFPFPSAPDEQMLESAEKRLCRLGALSEST 738

  Fly   952 ----AEDQLTPLGHHLAALPVDVRIGKLMLYGAIFQCLDSVLTIAACLSNKSPFVSPLNKRTEA- 1011
                .|.::|.||..||..|:.....|.:........:...:.:.:.||.:.|.:...:.|.:.
 Worm   739 KNGKTEARITKLGKTLAVFPLAPSYAKFIAMADQHNLMSHAILLISLLSVREPLIPVSSLRGDTP 803

  Fly  1012 DKCKRMFALGNSDHLTVLNAYRKWLDVARRGNYAASRNYASEHFLSLNTLETIADLKYQYLEL-L 1075
            ::.|.:..       .||...|:|.      ::..:|.......| ::.......:||...|. .
 Worm   804 EETKELMK-------NVLKERRRWC------SHTGARRLGDLKVL-MHAASVAEQIKYNARECEK 854

  Fly  1076 VSIGFVPIDVPRRRKNACDNILTLTGVEQNH-----------NGDNNRLLTSLLCAALYPNIVKI 1129
            |.:....:...|:.:....||:. ...::.|           .....:||..::.|:....:.:.
 Worm   855 VGLRVKALVEARKLRQQLTNIVN-ASCKKEHAAALDSDLPPPTDQQAQLLRQMVVASFSDRLARR 918

  Fly  1130 MTPDRVYIQTAGGAVPREPSHHDLRFKTRGDGYVKIHPSSVNSQVSVFQAPFLVFQEKVRTS 1191
            :  ||        :|.:|.........|...|:|.|.|.||   |...:..|:::||.|:.:
 Worm   919 V--DR--------SVGQEEVQKGAYETTLIKGHVFIDPCSV---VFTEEPEFVIYQELVQVN 967

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1582	NP_572663.1	UBA_like_SF	123..154	CDD:473871
		RWD_DHX57	175..367	CDD:467661	38/199 (19%)
		zf-CCCH	245..272	CDD:459885	5/26 (19%)
		HrpA	452..>1075	CDD:441249	193/683 (28%)
		OB_NTP_bind	1114..1212	CDD:400182	18/78 (23%)
rha-2	NP_498895.1	HrpA	234..>1020	CDD:441249	217/813 (27%)