Protein Alignment CG1582 and l(2)37Cb

DIOPT Version :10

• Sequence 1: NP_572663.1
• Gene: CG1582 / 32021
• FlyBaseID: FBgn0030246
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: XP_319843.5
• Gene: l(2)37Cb / 1280046
• VectorBaseID: AGAMI1_007561
• Length: 891
• Species: Anopheles gambiae
• Alignment Length: 1143
• Identity: 299/1143 - (26%)
• Similarity: 483/1143 - (42%)
• Gaps: 324/1143 - (28%)

  Fly   178 LDMRADEKEALESIFDKAYEEREANRVWNLKFRID---HLLAHSPSEVRKAREAVLAAAAAAAQA 239
            :....|.:::..| .|.:.|||..    :||.|.:   .|.....|..|.       .||::.:.
Mosquito     1 MSKNTDRRKSYSS-DDSSDEERHR----DLKERDEFSKRLKQRDESNTRN-------VAASSDKR 53

  Fly   240 ALDKKKKPPLRCRNFDRDGTCKYGPKCRFAHLPQ--QPTESDTTKKDSVDENDNELWFHVEVRFP 302
            ..|..|:  ||....||:   |..|:.|.....|  :..:.|...:...|..|:|..| .|....
Mosquito    54 GADAAKR--LRLETADRE---KLLPELRKQSRRQYLEKRKEDKVAELEADIRDDEYLF-PEAEIT 112

  Fly   303 PGSRYPYEAPFIYLKTTCHDIPHELRLRYARHLYKEAKEICRDGIPCVYSICDLLQSNEQLAGRL 367
            ...|              .|..|:.||......:::|:|:.|
Mosquito   113 ERER--------------RDREHKKRLLQIAKDHEKARELER----------------------- 140

  Fly   368 DTSAFPSPKRSLFYDEPAGGGVNPDAEHHQSPKPSH---------------YARGQTSRNDGGHQ 417
             ...:..||      :...|.:....|..:..:..|               |..|.....:..
Mosquito   141 -VQRYRMPK------DVKKGEMEEYVEVDERERMPHSEQKKWEAEQLASAVYGFGSKDAKERA-- 196

  Fly   418 RNVEAQTRENRRLLQQ---FVE-------RRKEERYQ---------KIIDGRKQLPAFAEIERIL 463
                ||.:|...||.:   |||       ::|:::.:         .|.:.:|.||.:...|.::
Mosquito   197 ----AQQQEYELLLDEQIDFVEALQMAGTKKKDDKPELTEAQRKKMTIEETQKSLPIYPFKEDLI 257

  Fly   464 ALIESSPVVVISGETGCGKSTQVPQFILDNWFFRALQLPAKENLPHVEIICTQPRRLSAIGVAER 528
            |.|::..:::|.||||.||:||:||::.:..|....:          :|.||||||::|:.||.|
Mosquito   258 AAIQAHNILIIEGETGSGKTTQIPQYLYEAGFTNEGK----------KIGCTQPRRVAAMSVAAR 312

  Fly   529 VAAERLDRIGQLVGYQIRLENKVSQSTRLSFCTTGILLRRLASDPLLGSVTHVIVDEVHERSEES 593
            ||.|...::|..|||.||.|:..|:.|.:.:.|.|.|.|...|:|.|.|...:|:||.|||:..:
Mosquito   313 VAEEMAVKLGNEVGYSIRFEDCTSERTVIKYMTDGTLHREFLSEPDLASYAVMIIDEAHERTLHT 377

  Fly   594 DFLLLILKNLLRERKDLKVILMSATLNAALFSDYFGGAPVLDIPGRTFPVQQLFLEDILEMSDFV 658
            |.|..::|::.|.|||||:::.||||:|..|||:|..||:..||||.:||      ||
Mosquito   378 DILFGLVKDIARFRKDLKLLISSATLDAEKFSDFFDKAPIFRIPGRRYPV------DI------- 429

  Fly   659 MEYDTKYCRKLKKQEQEILERELEYADVQASGEAPGKKIKDEKLTLAETYQRYAEYSKPTCKSIY 723
              :.||             ..|.:|.|                                .|
Mosquito   430 --FYTK-------------APEADYID--------------------------------AC---- 443

  Fly   724 LMEPMTINPELIESVLKYIVEGSHDWPREGTILIFLPGFGEIQSVHDSLLDNALFSPRAG----K 784
                       :.|||:.     |.....|.||:||.|..||::..:.|.|..   .|.|    :
Mosquito   444 -----------VVSVLQI-----HATQPLGDILVFLTGQEEIEACQEMLQDRV---KRLGSKLKE 489

  Fly   785 FILVPLHSALSGEDQALVFKKAPPGKRKIVLSTNIAETSVTIDDCVFVVDCGLMKEKCFDSNRNM 849
            .:::|:::.|..:.||.:|:..||..||::|:|||||||:|||:.::|:|.|..|:..|:|...|
Mosquito   490 LLILPIYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQNNFNSRTGM 554

  Fly   850 ESLDLVWVSRANAKQRKGRAGRVMPGVCIHLYTSYRYQYHILAQPVPEIQRVPLEQIVLRIKTLQ 914
            |:|.:|.:|:|:|.||.||||||.||.|..|||::.|...:....||||||:.|...||.:|||
Mosquito   555 ETLLVVPISKASANQRAGRAGRVAPGKCFRLYTAWAYNNELEDNTVPEIQRINLGNAVLMLKTL- 618

  Fly   915 TFASRNTLSVLL--ETLEAPTEDSVLGALTRLRDVGALDAEDQLTPLGHHLAALPVDVRIGKLML 977
                  .:..||  :.|:.|...:::.||.:|..:|||:...:||.||..:|..|||..:.|::|
Mosquito   619 ------GIHDLLHFDFLDPPPHQTLILALEQLYALGALNHHGELTKLGRRMAEFPVDPMMAKMLL 677

  Fly   978 YGAIFQCLDSVLTIAACLS-NKSPFVSPLNKRTEADKCKRMFALGNSDHLTVLNAYRKWLDVARR 1041
            ....::|.:.:::|||.|| |.:.|..|.:|...||..::.|...:.|||:::..|.:|::
Mosquito   678 ASEKYKCSEEIVSIAAMLSVNGAIFYRPKDKIIHADTARKNFNHRHGDHLSLMQVYNQWVE---- 738

  Fly  1042 GNYAASRNYASEHFLSLNTLETIADLKYQYLELL--VSIGFVPIDVPRRRKNACDNILTLTGVEQ 1104
            .:|  |..:..|:|:...:::...|::.|.:.|:  |.|..|
Mosquito   739 SDY--STQWCYENFIQYRSMKRARDVREQLVGLMQRVEIEMV----------------------- 778

  Fly  1105 NHNGDNNRLLTSLLCAALYPNIVKIMTPDRVYIQTAGGAVPREPSHHDLRFKTRGDGY------- 1162
              :|:::.           .|:.|.:|....|              |..|....|: |
Mosquito   779 --SGESDT-----------TNVRKAITAGYFY--------------HVARLSKSGN-YKTVKHNQ 815

  Fly  1163 -VKIHPSSVNSQVSVFQ--APFLVFQEKVRTSAIYIRDCSMLPLIAMVLFAGSDFKVELHDGDFL 1224
             |.|||:|     ::|:  ..:|::.|.|.|:..::|.                          :
Mosquito   816 DVMIHPNS-----ALFEDLPRWLLYHELVFTTKEFMRS--------------------------V 849

  Fly  1225 FLLESGWII------LKAHDLE---TAEMVQCL-RAEM 1252
            ..:||.|::      .|..:||   ..:|.:.: ||||
Mosquito   850 IEIESKWLLEVAPHYYKPKELEDPTNKKMPKTVGRAEM 887

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1582	NP_572663.1	UBA_like_SF	123..154	CDD:473871
		RWD_DHX57	175..367	CDD:467661	38/193 (20%)
		zf-CCCH	245..272	CDD:459885	8/26 (31%)
		HrpA	452..>1075	CDD:441249	208/629 (33%)
		OB_NTP_bind	1114..1212	CDD:400182	19/107 (18%)
l(2)37Cb	XP_319843.5	None