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Protein Alignment CG1582 and TDRD9

DIOPT Version :9

Sequence 1:	NP_001285098.1	Gene:	CG1582 / 32021	FlyBaseID:	FBgn0030246	Length:	1288	Species:	Drosophila melanogaster
Sequence 2:	NP_694591.2	Gene:	TDRD9 / 122402	HGNCID:	20122	Length:	1382	Species:	Homo sapiens

Alignment Length:	986	Identity:	283/986 - (28%)
Similarity:	434/986 - (44%)	Gaps:	211/986 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   359 SNEQLAGRLDTSAFPS-PKRSLFYDEPAGGGVNPDAEH---HQSP-KP-SHYARGQTSRNDG--- 414
            :|.:|.|.  ..|||: ..|.....:....|..|.|:.   .|:| :| :.:.|..:.|:..
Human    21 TNVELLGA--PPAFPAGAAREEVQRQDVAPGAGPAAQAPALAQAPARPAAAFERSLSQRSSEVEY 83

  Fly   415 -GHQRNVEAQTRENRRLLQQFVERRKEERYQKI-----IDGR----KQLPAFAEIERILALIESS 469
             ...|.:|||..:..|.:|............|:     |.|.    ..||.....|.:::||||:
Human    84 INKYRQLEAQELDVCRSVQPTSGPGPRPSLAKLSSVTCIPGTTYKYPDLPISRYKEEVVSLIESN 148

  Fly   470 PVVVISGETGCGKSTQVPQFILDNWFFRALQLPAKENLPHVEIICTQPRRLSAIGVAERVAAERL 534
            .||:|.|.||.|||||:||:|||::..|:         .:..|:.||||::.|..:|..::.||.
Human   149 SVVIIHGATGSGKSTQLPQYILDHYVQRS---------AYCSIVVTQPRKIGASSIARWISKERA 204

  Fly   535 DRIGQLVGYQIRLENKVSQSTRLSFCTTGILLRRLASDPLLGSVTHVIVDEVHERSEESDFLLLI 599
            ..:|.:||||:.||...::.|||.:.|||:||:::.|...|...||:|:||||||:||.|||||:
Human   205 WTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAKSLMEFTHIIIDEVHERTEEMDFLLLV 269

  Fly   600 LKNLLR-ERKDLKVILMSATLNAALFSDYF--------GGAPVLDIPGRTFPVQQLFLEDILEMS 655
            ::.||| ..:.:||:|||||::...|:|||        ..|.:.::.|:...|::.:|.|:
Human   270 VRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNKMNPAYIFEVEGKPHSVEEYYLNDL---- 330

  Fly   656 DFVMEYDTKYCRKLKKQEQEILERELEYADVQASGEAPGKKIKDEKLTLAETYQRYAEYSKPTCK 720
                                                   :.|...||
Human   331 ---------------------------------------EHIHHSKL------------------ 338

  Fly   721 SIYLMEPMTINPELIESVLKYI---------VEGSHDWP------REGTILIFLPGFGEIQSVHD 770
            |.:|:|...|..::.|..:..|         ..|:..|.      ...::|:||||.|||..:|:
Human   339 SPHLLEEPVITKDIYEVAVSLIQMFDDLDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHE 403

  Fly   771 SLLDNALFSPRAGKFILVPLHSALSGEDQALVFKKAPPGKRKIVLSTNIAETSVTIDDCVFVVDC 835
            .|  .:|...|...:   ||||:::.|:|..||....||.|||:|||||||:|||:.|..:|:|.
Human   404 LL--TSLVHKRLQVY---PLHSSVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDF 463

  Fly   836 GLMKEKCFDSNRNMESLDLVWVSRANAKQRKGRAGRVMPGVCIHLYTSYRYQYHILAQPVPEIQR 900
            .|.:....|.:.|.:||.|.|.|:.:..|||||||||..|.|..|.....:...|....|||:.|
Human   464 CLTRTLVCDEDTNYQSLRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLR 528

  Fly   901 VPLEQIVLRIKTLQTFASRNTLSVLLETLEAPTEDSVLGALTRLRDVGAL----DAED------Q 955
            .||...:|::|.|.....|   ::|...|..|....:...:..|::||||    ..||      :
Human   529 CPLGSTILKVKLLDMGEPR---ALLATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGE 590

  Fly   956 LTPLGHHLAALPVDVRIGKLMLYGAIFQCLDSVLTIAACLSNKSPFVSPLNKRTEADKCKRMFA- 1019
            ||.||..||.|||:.::|||::.|.:|.|||..|.|||.||.|:.|..|..:..:..:.|..|:
Human   591 LTFLGRVLAQLPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGYRNKVNFSG 655

  Fly  1020 LGNSDHLTVLNAYRKWLDVARRGNYAASR---NYASEHFLSLNTLETIADLKYQYLELLVSIGFV 1081
            ...||.:.::.|::.|....:.|.....:   |:...:::.:..:..:|:|   |.||...|...
Human   656 SSKSDCIALVEAFKTWKACRQTGELRYPKDELNWGRLNYIQIKRIREVAEL---YEELKTRISQF 717

  Fly  1082 PIDVPRRRKNACDNILTLTGVEQNHNGDNNRLLTSLLCAALYPNIVKIMTPD-RVYIQTAGGAVP 1145
            .:.|..||          ..::|.:......:|..:|..|.|||......|| .:.::...|..|
Human   718 NMHVDSRR----------PVMDQEYIYKQRFILQVVLAGAFYPNYFTFGQPDEEMAVRELAGKDP 772

  Fly  1146 RE-------PSHHDLRFKT-----RGDGYVKIHPSSVNSQVSVFQA--PFLVFQ----EKVRTSA 1192
            :.       |.:..|.:|.     |..|.||    |:     ||..  .|:.|.    |:.:|
Human   773 KTTVVLKHIPPYGFLYYKQLQSLFRQCGQVK----SI-----VFDGAKAFVEFSRNPTERFKT-- 826

  Fly  1193 IYIRDCSMLPLIAMVLFAGSDFKVELHDGDFLFLLESGWIILKAHDLETAE-MVQCLRAEMIKLL 1256
                    ||.:.|.: ..|..||.|.              |..|..|..| .||.:..
Human   827 --------LPAVYMAI-KMSQLKVSLE--------------LSVHSAEEIEGKVQGMNV------ 862

  Fly  1257 EEKIRDPCLNL 1267
             .|:|:..:|:
Human   863 -SKLRNTRVNV 872

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.