DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1582 and dhx36

DIOPT Version :9

Sequence 1:	NP_001285098.1	Gene:	CG1582 / 32021	FlyBaseID:	FBgn0030246	Length:	1288	Species:	Drosophila melanogaster
Sequence 2:	XP_002933292.1	Gene:	dhx36 / 100495115	XenbaseID:	XB-GENE-960425	Length:	981	Species:	Xenopus tropicalis

Alignment Length:	1015	Identity:	384/1015 - (37%)
Similarity:	569/1015 - (56%)	Gaps:	154/1015 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   324 PH----ELRLRYARHLYKEAKEICRDGIPCVYSICDLLQSNEQLAGRL-------DTSAFPS-PK 376
            ||    |:.|.:||...:.:||..|.    ..::..:.:|.||...||       :.:..|| ..
Frog    48 PHLKGREIGLWHARRQGQRSKEKERQ----ERAVVKMDESREQHITRLLNSVQAQNNNERPSCSD 108

  Fly   377 RSLFYDEPAGGGVNPDAEHHQSPKPSHYARGQTSRNDGGHQRNVEAQTRENRRLLQQFVERRKEE 441
            .|.:..|.....|:...:....|:...:|.......:..     ||.|..:::|.::..|:|...
Frog   109 ESWWATENERNSVSTQLKQPAMPEEKDHAWDSEYAAEAD-----EAGTDLDQQLKEELHEKRTNY 168

  Fly   442 RYQKIIDGRKQLPAFAEIERILALIESSPVVVISGETGCGKSTQVPQFILDNWFFRALQLPAKEN 506
            :|.::...|::||:::..|.|:.:|.|:.|.||||||||||:|||.|||||:
Frog   169 KYLEMQKFREKLPSYSMKEMIIKMINSNQVTVISGETGCGKTTQVTQFILDD------------- 220

  Fly   507 LPHVE--------IICTQPRRLSAIGVAERVAAERLDRIGQ--LVGYQIRLENKVSQST-RLSFC 560
              |::        |:||||||:|||.|||||||||.:..|:  ..|||||||:::.:.. .:.:|
Frog   221 --HIKRGKGSSCYIVCTQPRRISAISVAERVAAERAEACGRGNSTGYQIRLESQMPRKQGSILYC 283

  Fly   561 TTGILLRRLASDPLLGSVTHVIVDEVHERSEESDFLLLILKNLLRERKDLKVILMSATLNAALFS 625
            ||||:::.|.|||.|.:|:||::||:|||:.:||.|:.|:|:||..|.|||||||||||||..||
Frog   284 TTGIVIQWLQSDPHLANVSHVVIDEIHERNLQSDVLMAIVKDLLTFRSDLKVILMSATLNAEKFS 348

  Fly   626 DYFGGAPVLDIPGRTFPVQQLFLEDILEM-------SDFVMEYDTKY------CRKLKKQEQEIL 677
            .||...|:|.|||.|:||::..|||::||       ||...::..::      |.:.:::||...
Frog   349 QYFDSCPMLHIPGFTYPVKEYLLEDVIEMLRYMPKDSDRRPQWKKRFMQGRMMCTEKEEKEQLYR 413

  Fly   678 ERELEYADVQASGEAPGKKIKDEKLTLAETYQRYAEYSKPTCKSIYLMEPMTINPELIESVLKYI 742
            ||..|:.               .||      ||  .||:.|.:::.|.:...::.:||..:::||
Frog   414 ERWPEFV---------------RKL------QR--RYSESTIEALELADDEKVDLDLIAELIRYI 455

  Fly   743 VEGSHDWPREGTILIFLPGFGEIQSVHDSLLDNALFSPRAGKFILVPLHSALSGEDQALVFKKAP 807
            |....|    |.||:||||:..|.:::|.|:...:|  ::.|||::||||.:...:|..|||:.|
Frog   456 VLKGED----GAILVFLPGWDNISTLNDLLMSQVMF--KSDKFIIIPLHSLMPTVNQTEVFKRPP 514

  Fly   808 PGKRKIVLSTNIAETSVTIDDCVFVVDCGLMKEKCFDSNRNMESLDLVWVSRANAKQRKGRAGRV 872
            ||.||||::|||||||:||||.|.|:|.|.:||..||:..|:.::...|||.|||||||||||||
Frog   515 PGVRKIVIATNIAETSITIDDVVHVIDGGKIKETHFDTQNNISTMTAEWVSHANAKQRKGRAGRV 579

  Fly   873 MPGVCIHLYTSYR------YQYHILAQPVPEIQRVPLEQIVLRIKTLQTFASRNTLSVLLETLEA 931
            .||.|.|||.|.|      ||       :|||.|.|||::.|:||.|:.....:.|..|::|
Frog   580 QPGHCYHLYNSLRDSLLDDYQ-------LPEIVRTPLEELCLQIKILKLGGIASFLRKLMDT--- 634

  Fly   932 PTEDSVLGALTRLRDVGALDAEDQLTPLGHHLAALPVDVRIGKLMLYGAIFQCLDSVLTIAACLS 996
            |:.|::..|:..|.::.|||..::|||||.|||.|||:..|||::|:||:|.|||.||||||.||
Frog   635 PSRDTICLAINHLMELNALDKREELTPLGFHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLS 699

  Fly   997 NKSPFVSPLNKRTEAD-KCKRMFALGNSDHLTVLNAYRKWLDVARRGNYAASRNYASEHFLSLNT 1060
            .|.|||.||.|...|| :.|.:.....|||||||||:..|.|...||. .|.|:|..|:|||.|:
Frog   700 FKDPFVIPLGKEKLADARRKELSRNSKSDHLTVLNAFEGWEDAKWRGG-RAERDYCWENFLSSNS 763

  Fly  1061 LETIADLKYQYLELLVSIGFVPIDVPRRRKNACDNILTLTGVEQNHNGDNNRLLTSLLCAALYPN 1125
            |:.::::|.|:.|.|:|.|||....|...|:             |.|..|.:|:.:::||.|||.
Frog   764 LKMLSNMKGQFAEHLLSAGFVSSRSPNDPKS-------------NINSTNEKLIKAVICAGLYPK 815

  Fly  1126 IVKIMTPD--------RVYIQTAGGAVPREPSHHDLRFKTRGDGYVKIHPSSVNSQVSVFQAPFL 1182
            :.|| .|:        :||                    |:.||.|.|||.|||.:.:.|...:|
Frog   816 VAKI-RPNFGKRRKMVKVY--------------------TKSDGKVNIHPKSVNVEETEFHYSWL 859

  Fly  1183 VFQEKVRTSAIYIRDCSMLPLIAMVLFAGSDFKVELHDGDFLFLLESGWIILKAHDLETAEMVQC 1247
            |:..|:||::||:.||:.:...:: ||.|.|..:: .|.|...:....||:.:: ....|.:|:.
Frog   860 VYHLKMRTTSIYLYDCTEVSPYSL-LFFGGDISIQ-KDKDQDTIAVDEWIVFQS-PARIAHLVKD 921

  Fly  1248 LRAEMIKLLEEKIRDP-CLNLLHHKN-GCRMIANIVHLIS 1285
            |::|:..||:|||..| .::....|: .|.:::.|:.||:
Frog   922 LKSELDVLLKEKIEKPQPVDWKETKSRDCAVLSAIIDLIT 961

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1582	NP_001285098.1	UBA_like_SF	123..154	CDD:304366
		zf-CCCH	250..272	CDD:279036
		RWD	<284..360	CDD:283440	9/39 (23%)
		HrpA	419..1206	CDD:224557	340/825 (41%)
		DEXDc	471..619	CDD:238005	82/158 (52%)
		HELICc	781..871	CDD:197757	51/89 (57%)
		HA2	948..1029	CDD:214852	47/81 (58%)
		OB_NTP_bind	1070..1212	CDD:285018	45/149 (30%)
dhx36	XP_002933292.1	HrpA	130..926	CDD:224557	353/892 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D222681at33208
OrthoFinder	1	1.000	-	-		FOG0000258
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X384
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010