Protein Alignment Ork1 and Kcnk9

DIOPT Version :10

• Sequence 1: NP_001285097.1
• Gene: Ork1 / 32020
• FlyBaseID: FBgn0017561
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_445857.2
• Gene: Kcnk9 / 84429
• RGDID: 621451
• Length: 396
• Species: Rattus norvegicus
• Alignment Length: 325
• Identity: 87/325 - (26%)
• Similarity: 144/325 - (44%)
• Gaps: 58/325 - (17%)

  Fly     5 RWILLLIFYISYLMFGAAIYYHIE-----HGEEKISRAEQR---KAQIAINEYLLEELGDKNTTT 61
            |.:.|:....:||:.|||::..:|     ..|||:...|.|   |..|:.::|...||
  Rat     7 RTLSLIACTFTYLLVGAAVFDALESDHEMREEEKLKAEEVRLRGKYNISSDDYQQLEL------- 64

  Fly    62 QDEILQRISDYCDKPVTLPPTYDDTPY----TWTFYHAFFFAFTVCSTVGYGNISPTTFAGRMIM 122
              .|||                 ..|:    .|.|..:|:||.||.:|:|||:.:|.|.||:...
  Rat    65 --VILQ-----------------SEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFC 110

  Fly   123 IAYSVIGIPVNGILFAGLGEYFGRTFEAIYRRYKKYKMSTDMHYVPPQLGLITTVVIALIPGIAL 187
            :.|:|:|||:..::|..|||........:.:|.||   ...|......:..:.||......|.
  Rat   111 MFYAVLGIPLTLVMFQSLGERMNTFVRYLLKRIKK---CCGMRNTEVSMENMVTVGFFSCMGT-- 170

  Fly   188 FLLLPSWVFTYFENWPYSISLYYSYVTTTTIGFGDYV--PTFGANQPKEFGGWFVVYQIFVIVWF 250
             |.|.:..|:..|:|.:..:.||.::|.|||||||:|  .:.||.|.|.|   :|.:....|:..
  Rat   171 -LCLGAAAFSQCEDWSFFHAYYYCFITLTTIGFGDFVALQSKGALQRKPF---YVAFSFMYILVG 231

  Fly   251 IFSLGYL--VMIMTFITRGLQSKKLAYLEQQLSSNLKATQNRIWSGVTKDVGYLRRMLNELYILK 313
            :..:|..  ::::.|:|......   .||.:::..|.....|:...|.:.    |:..:.:|.|:
  Rat   232 LTVIGAFLNLVVLRFLTMNTDED---LLEGEVAQILAGNPRRVVVRVPQS----RKRHHPMYFLR 289

  Fly   314  313
              Rat   290  289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	83..144	CDD:462301	25/64 (39%)
		Ion_trans_2	185..266	CDD:462301	25/84 (30%)
Kcnk9	NP_445857.2	Ion_trans_2	<73..132	CDD:462301	24/58 (41%)
		Selectivity filter 1. /evidence=ECO:0000250|UniProtKB:Q9NPC2	93..98		3/4 (75%)
		Ion_trans_2	<184..243	CDD:462301	20/61 (33%)
		Selectivity filter 2. /evidence=ECO:0000250|UniProtKB:Q9NPC2	199..204		4/4 (100%)
		X-gate. /evidence=ECO:0000250|UniProtKB:Q9NPC2	243..248		1/4 (25%)