Protein Alignment Ork1 and KCNK16

DIOPT Version :9

• Sequence 1: NP_001285097.1
• Gene: Ork1 / 32020
• FlyBaseID: FBgn0017561
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_001128577.1
• Gene: KCNK16 / 83795
• HGNCID: 14464
• Length: 322
• Species: Homo sapiens
• Alignment Length: 226
• Identity: 77/226 - (34%)
• Similarity: 117/226 - (51%)
• Gaps: 25/226 - (11%)

  Fly     5 RWILLLIFYISYLMFGAAIYYHIEHGEEKISRAEQRKAQIAINEYLLEELGD-KNTTTQD----- 63
            |.:.||:.|:.||:.||.|:..:|...|..||          :::.||:|.. :|.|..|
Human    13 RVLPLLLAYVCYLLLGATIFQLLERQAEAQSR----------DQFQLEKLRFLENYTCLDQWAME 67

  Fly    64 EILQRISDYCDKPVTLPPTYDDTPYTWTFYHAFFFAFTVCSTVGYGNISPTTFAGRMIMIAYSVI 128
            :.:|.|.:...|.|. |......|..|.|..:||||.||.:|:||||::|:|.||::..:.|:::
Human    68 QFVQVIMEAWVKGVN-PKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALL 131

  Fly   129 GIPVNGILFAGLGEYFGRTFEAIYRRYKKYKMSTDMHYVPPQLGLITTVVIALIPGIALFLLLPS 193
            |||:|.|....||........||.|...:.:.|    .|...|||    .:.|..|..:.|:.|.
Human   132 GIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRS----QVLQVLGL----ALFLTLGTLVILIFPP 188

  Fly   194 WVFTYFENWPYSISLYYSYVTTTTIGFGDYV 224
            .||::.|.|.:|...|::::|.:||||||||
Human   189 MVFSHVEGWSFSEGFYFAFITLSTIGFGDYV 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	<90..144	CDD:285168	25/53 (47%)
		Ion_trans_2	185..269	CDD:285168	17/40 (43%)
KCNK16	NP_001128577.1	Ion_trans_2	<92..148	CDD:311712	25/55 (45%)
		Ion_trans_2	180..>224	CDD:311712	17/40 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155184
Domainoid	1	1.000	65	1.000	Domainoid score	I10023
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	1	1.000	-	-		otm41289
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.800