Protein Alignment Ork1 and Kcnk12

DIOPT Version :10

• Sequence 1: NP_001285097.1
• Gene: Ork1 / 32020
• FlyBaseID: FBgn0017561
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: XP_038968799.1
• Gene: Kcnk12 / 64119
• RGDID: 68940
• Length: 521
• Species: Rattus norvegicus
• Alignment Length: 525
• Identity: 100/525 - (19%)
• Similarity: 162/525 - (30%)
• Gaps: 194/525 - (36%)

  Fly     5 RWILLLIFYISYLMFGAAIYYHIEHGEEKISRAEQRKAQIAINEYLLEELGDKNTTTQDEILQRI 69
            |::||......||:.||.::..:|...|..:||.....        |......:...:.|:...:
  Rat    38 RFVLLAALIGLYLVAGATVFSALESPGEAEARARWGAT--------LRNFSAAHGVAEPELRAFL 94

  Fly    70 SDYCDKPVTLPPTYDDTPYTWTFYHAFFFAFTVCSTV---------------------------- 106
            ..| :..:......|.....|.|..||:|..||.||:
  Rat    95 RHY-EAALAAGVRADALRPRWDFPGAFYFVGTVVSTIDSQIPTAAVCRHPKADQFMHPRPCVQLL 158

  Fly   107 ---------------------------------------------------------------GY 108
                                                                           |:
  Rat   159 GLSQSRSLATMLLKFQSSKLSTITPSTHWAFPVTPPLARGRGTSFRRRCCGCTWRLGLSVACPGF 223

  Fly   109 GNISPTTFAGRMIMIAYSVIGIPVNGILFAGLGEYFGRTFE---------------------AIY 152
            |..:|.|..|:..:|||.:.|. ...|||..|  :..|...                     |.:
  Rat   224 GMTTPATVGGKAFLIAYGLFGC-AGTILFFNL--FLERIISLLAFIMRACRERQLRRSGLLPATF 285

  Fly   153 RRYKKYKMSTDMHYVPPQLGLITTVVIALIPGIALFLL--LPSWVFTYFENWPYSISLYYSYVTT 215
            ||......:..:....|     :...:.||.|:...||  ..|.::|..|.|.|..|||:.:||.
  Rat   286 RRGSALSEADSLAGWKP-----SVYHVLLILGLFAVLLACCASAMYTSVEGWDYVDSLYFCFVTF 345

  Fly   216 TTIGFGDYVPTFGA---NQPKEFGGWFVVYQIFVI--VWFIFSLGYLVMIMTFITRGLQSKKLAY 275
            :||||||.|.:..|   ||.....|.|    :|::  |..|:||..::.|:
  Rat   346 STIGFGDLVSSQHAAYRNQGLYRLGNF----LFILLGVCCIYSLFNVISIL-------------- 392

  Fly   276 LEQQLSSNLKATQNRIWSGVTKDVGYLRRMLNELYILKVKFCRKGNRKKPKNKAKTEQKKKSSRY 340
                                      ::::||  ::|:...||...|..|...|..      ||.
  Rat   393 --------------------------IKQVLN--WMLRKLSCRCCTRCCPAPGAPL------SRR 423

  Fly   341 IAYTLPRSNSCPDLSMYRVEPAPIPSRKRAFSVCADMVAAQREAGMVHANSDTELSKLDREKTFE 405
            .|.| |.|.....|:....:||...|......:..::::.:.    :.|::...|:.|.::.: |
  Rat   424 NAIT-PGSRLRRRLAALGTDPAARDSDAEGRRLSGELISMRD----LTASNKVSLALLQKQLS-E 482

  Fly   406 TAEAY 410
            ||..|
  Rat   483 TANGY 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	83..144	CDD:462301	23/151 (15%)
		Ion_trans_2	185..266	CDD:462301	30/87 (34%)
Kcnk12	XP_038968799.1	Ion_trans_2	313..395	CDD:462301	30/125 (24%)