Protein Alignment Ork1 and KCNK13

DIOPT Version :9

• Sequence 1: NP_001285097.1
• Gene: Ork1 / 32020
• FlyBaseID: FBgn0017561
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_071337.2
• Gene: KCNK13 / 56659
• HGNCID: 6275
• Length: 408
• Species: Homo sapiens
• Alignment Length: 391
• Identity: 93/391 - (23%)
• Similarity: 158/391 - (40%)
• Gaps: 77/391 - (19%)

  Fly     5 RWILLLIFYISYLMFGAAIYYHIE--HGEEKISRAEQRKAQIAINEYLLEELGDKNTTTQDEILQ 67
            |::||....:.||:.|||::..:|  |..:...|.|:|.|..:....|          ::||:..
Human    19 RFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHNL----------SRDELRG 73

  Fly    68 RISDYCDKPVTLPPTYDDTPYTWTFYHAFFFAFTVCSTVGYGNISPTTFAGRMIMIAYSVIGIPV 132
            .:..| ::........|:....|.|..||:|..||.||:|:|..:|.|..|::.:|.|.::|..
Human    74 FLRHY-EEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCS- 136

  Fly   133 NGILFAGLGEYFGRTFEAI-YRRYKKYKMSTDMHYVPPQLGL-----------------ITTVVI 179
            :.|||..|  :..|....| |.....::.........||..|                 :..|::
Human   137 STILFFNL--FLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPSVYYVML 199

  Fly   180 ALIPGIALFLLLPSWVFTYFENWPYSISLYYSYVTTTTIGFGDYVPTFGANQPKEFGGWFVVYQI 244
            .|.....|.....|.::|..|.|.|..|||:.:|..:||||||.|.:..|:...: |.:.....:
Human   200 ILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHYESQ-GLYRFANFV 263

  Fly   245 FVI--VWFIFSLGYLVMI-----MTFITRGLQSKKLAYLEQQLSSNLKATQNRIWSGVTKDVGYL 302
            |::  |..|:||..::.|     :.:|.|.:.|......::.|   |::.:|.:..|..::...:
Human   264 FILMGVCCIYSLFNVISILIKQSLNWILRKMDSGCCPQCQRGL---LRSRRNVVMPGSVRNRCNI 325

  Fly   303 --------------RRMLNELYILKVKFCRKGNRKKPKNKAKTE--QKKKSSRYIAYTLPRSNSC 351
                          ||:..|:..:|....        .|||...  ||:.|.        .:|.|
Human   326 SIETDGVAESDTDGRRLSGEMISMKDLLA--------ANKASLAILQKQLSE--------MANGC 374

  Fly   352 P 352
            |
Human   375 P 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	<90..144	CDD:285168	21/53 (40%)
		Ion_trans_2	185..269	CDD:285168	27/90 (30%)
KCNK13	NP_071337.2	Ion_trans_2	<94..150	CDD:311712	22/58 (38%)
		Ion_trans_2	206..285	CDD:311712	25/79 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155144
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840