Protein Alignment Ork1 and kcnk2a

DIOPT Version :10

• Sequence 1: NP_001285097.1
• Gene: Ork1 / 32020
• FlyBaseID: FBgn0017561
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: XP_021323122.1
• Gene: kcnk2a / 559728
• ZFINID: ZDB-GENE-061226-2
• Length: 426
• Species: Danio rerio
• Alignment Length: 413
• Identity: 109/413 - (26%)
• Similarity: 173/413 - (41%)
• Gaps: 113/413 - (27%)

  Fly     5 RW---ILLLIFYISYLMFGAAIYYHIEHGEEKIS--RAEQRKAQI-----AINEYLLEELGDKNT 59
            :|   :.:.:..:.||:.||.::..:|..||.:.  |..|.|...     .:|...||:|
Zfish    56 KWKTVLAIFLLVVLYLIIGATVFKALEQPEEGLQKYRIIQEKIDFLSMHTCVNTSELEDL----- 115

  Fly    60 TTQDEILQRISDYCDKPVTLP----------PTYDDTPYTWTFYHAFFFAFTVCSTVGYGNISPT 114
                          .|.|.|.          |:.:.:  .|....:||||.||.:|:|:||:||.
Zfish   116 --------------VKQVVLAIRAGVNPSGHPSNESS--MWDLSSSFFFAGTVITTIGFGNVSPH 164

  Fly   115 TFAGRMIMIAYSVIGIPVNGILFAG----LGEYFGRTFEAIYRRYKKYKMS-TDMHYVPPQLGLI 174
            |..||:..|.|:::|||:.|.|.||    ||..||:....:.:.:.|:.:| |.:.        :
Zfish   165 TEGGRIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEKMFVKWNVSQTKIR--------V 221

  Fly   175 TTVVIALIPGIALFLLLPSWVFTYFENWPYSISLYYSYVTTTTIGFGDYVPTFGANQPKEFGGWF 239
            |:.|:.::.|..||:.||:.:|.:.|.|....|:|:..:|.|||||||:|.          ||..
Zfish   222 TSTVLFILFGCLLFVALPALIFQHIEGWSALESIYFVVITLTTIGFGDFVA----------GGSE 276

  Fly   240 VVYQIFV--IVWF--IFSLGYLVMIMTFITRGLQ--SKK-----------LAYLEQQLSSNLKAT 287
            :.|..:.  ||||  :..|.|...:::.|...|:  |||           .|.....:|:..|.|
Zfish   277 IEYLDYYKPIVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVSAEFKET 341

  Fly   288 QNRIWSGV---TKDVGYLRRML-NEL------------YILKVKFC----RKGNRKKPKNKAKTE 332
            :.|:...:   .:...|::|.| :||            ..|.|.|.    ::|.....||
Zfish   342 RRRLSVEIYDKFQRAAYIKRKLSSELGQNPGQDMMPCKRTLSVNFTDELEKEGLPTLTKN----- 401

  Fly   333 QKKKSSRYIAYTLPRSNSCPDLS 355
                .|.|:....|   .|||.|
Zfish   402 ----GSLYLNGLTP---DCPDCS 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	83..144	CDD:462301	27/64 (42%)
		Ion_trans_2	185..266	CDD:462301	28/84 (33%)
kcnk2a	XP_021323122.1	Ion_trans_2	<136..194	CDD:462301	25/59 (42%)
		Ion_trans_2	232..310	CDD:462301	28/87 (32%)