Protein Alignment Ork1 and KCNK10

DIOPT Version :9

• Sequence 1: NP_001285097.1
• Gene: Ork1 / 32020
• FlyBaseID: FBgn0017561
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_612190.1
• Gene: KCNK10 / 54207
• HGNCID: 6273
• Length: 543
• Species: Homo sapiens
• Alignment Length: 319
• Identity: 85/319 - (26%)
• Similarity: 153/319 - (47%)
• Gaps: 43/319 - (13%)

  Fly     5 RW---ILLLIFYISYLMFGAAIYYHIEHGEEK-------ISRAEQRKAQIAINEYLLEELGDKNT 59
            :|   :.:.:..:.||:.|..::..:|...|.       :.:||..:..:.::...||.|
Human    73 KWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETL----- 132

  Fly    60 TTQDEILQRISDYCDKPVTLPPTYDDTPYTWTFYHAFFFAFTVCSTVGYGNISPTTFAGRMIMIA 124
                  :|...|..:..|:......:....|....|||||.||.:|:|||||:|:|..|::..|.
Human   133 ------IQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCIL 191

  Fly   125 YSVIGIPVNGILFAGLGE----YFGRTFEAIYRRYKKYKMSTDMHYVPPQLGLITTVVIALIPGI 185
            |::.|||:.|.|.||:|:    .||::...:.:.::|.::|      ..::.:|:|::. ::.|.
Human   192 YAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVS------QTKIRVISTILF-ILAGC 249

  Fly   186 ALFLLLPSWVFTYFENWPYSISLYYSYVTTTTIGFGDYVPTFGANQPKEFGGWFVVYQIFVIVWF 250
            .:|:.:|:.:|.|.|.|....|:|:..||.||:||||:|.  |.|....:..|   |:..|..|.
Human   250 IVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVA--GGNAGINYREW---YKPLVWFWI 309

  Fly   251 IFSLGYLVMIMTFITRGLQ--SKKLAYLEQQLSSNLKATQNRIWSGVTKDVGYLRRMLN 307
            :..|.|...:::.|...|:  |||    .::....:||......:.||.:....||.|:
Human   310 LVGLAYFAAVLSMIGDWLRVLSKK----TKEEVGEIKAHAAEWKANVTAEFRETRRRLS 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	<90..144	CDD:285168	27/57 (47%)
		Ion_trans_2	185..269	CDD:285168	26/83 (31%)
KCNK10	NP_612190.1	Ion_trans_2	153..211	CDD:285168	27/57 (47%)
		Ion_trans_2	249..328	CDD:285168	26/83 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155147
Domainoid	1	1.000	65	1.000	Domainoid score	I10023
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	154	1.000	Inparanoid score	I4331
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	1	1.000	-	-		otm41289
orthoMCL	1	0.900	-	-		OOG6_108298
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.790