Protein Alignment Ork1 and Kcnk5

DIOPT Version :10

• Sequence 1: NP_001285097.1
• Gene: Ork1 / 32020
• FlyBaseID: FBgn0017561
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_001034605.1
• Gene: Kcnk5 / 364241
• RGDID: 1564985
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 533
• Identity: 131/533 - (24%)
• Similarity: 216/533 - (40%)
• Gaps: 99/533 - (18%)

  Fly     4 NRWILLLIFYISYLMFGAAIYYHIEHGEEKISRAEQRKAQIAINEYLLEELGDKNTTTQDEILQR 68
            :|..||....|.||..||||:..:|....|    |.:|.......:||:|....:....|:|||.
  Rat     3 DRGPLLTSAIIFYLAIGAAIFEVLEEPHWK----EAKKNYYTQKLHLLKEFPCLSQEGLDKILQV 63

  Fly    69 ISDYCDKPVTLPPTYDDTPYTWTFYHAFFFAFTVCSTVGYGNISPTTFAGRMIMIAYSVIGIPVN 133
            :||..|:.|.:  |.:.|...|.:.:|..||.||.:|:||||::|.|.|||:..:.|.:.|:|:.
  Rat    64 VSDAADQGVAI--TGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLC 126

  Fly   134 GILFAGLGEYFGRTFEAIYRRYKKYKMSTDMHYVPPQLGLITTVVIALIPGIALFLLLPSWVFTY 198
            ....:.||::||       .|.|:.........|..:...||...|.::.|:.:.|::|.:||..
  Rat   127 LTWISALGKFFG-------GRAKRLGQFLTRRGVSLRKAQITCTAIFIVWGVLVHLVIPPFVFMV 184

  Fly   199 FENWPYSISLYYSYVTTTTIGFGDYVPTFGANQPKEFGGWFVVYQIFVIVWFIFSLGYLVMIMTF 263
            .|.|.|...||||::|.:||||||:|.  |.|..   ..:..:|:.||.:|....|.:|.:.:.:
  Rat   185 TEEWNYIEGLYYSFITISTIGFGDFVA--GVNPS---ANYHALYRYFVELWIYLGLAWLSLFVNW 244

  Fly   264 -------ITRGLQSKKLAYLEQQLSS--NLKATQNRIWSGVTKDV---GYLRRMLNELYILKVKF 316
                   :.:.::.::....|...||  :.||.| ...|..:|||   .:|.:. .|.|...:|
  Rat   245 KVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQ-MAGSTASKDVNIFSFLSKK-EETYNDLIK- 306

  Fly   317 CRKGNRKKPKNKAKTEQKKKSSRYIAY-------TLPRSNSCPDLSMYRVEPAPIPSRKRAFSVC 374
              :..:|..|.....|:.......:..       ::|.|          :.|..:.|:.|..|:
  Rat   307 --QIGKKAMKTSGGGERVPGPGHGLGAQGGDGLPSIPAS----------LAPLVVYSKNRVPSL- 358

  Fly   375 ADMVAAQREAGMV----------------HANSDTELSKLDR---------------------EK 402
            .::....|..|.|                :..|:..:::|||                     ..
  Rat   359 EEVSQTLRNKGHVSRPLGEDAAAQTPKEGYPTSEVFINQLDRISEEGEPWEALDYHPLIFQNANI 423

  Fly   403 TFETAEAYRQTTDLLAKVVNALATVK----PPPAEQEDAALYGGYHGFSDSQILASEWSFST--- 460
            |||..|......:.....|....|.|    |.|..:..::..|.:....:|...::|...|.
  Rat   424 TFENEETGLSDEETSKSSVEDNLTSKEQPQPGPMTEVPSSSTGEFPSSDESTFTSTESELSVPYE 488

  Fly   461 --VNEFTSPRRPR 471
              :||:.....||
  Rat   489 KLMNEYNKADSPR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	83..144	CDD:462301	22/60 (37%)
		Ion_trans_2	185..266	CDD:462301	27/87 (31%)
Kcnk5	NP_001034605.1	Ion_trans_2	<83..137	CDD:462301	21/53 (40%)
		Ion_trans_2	171..243	CDD:462301	27/76 (36%)