Protein Alignment Ork1 and twk-7

DIOPT Version :10

• Sequence 1: NP_001285097.1
• Gene: Ork1 / 32020
• FlyBaseID: FBgn0017561
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_498903.3
• Gene: twk-7 / 192073
• WormBaseID: WBGene00006662
• Length: 557
• Species: Caenorhabditis elegans
• Alignment Length: 414
• Identity: 99/414 - (23%)
• Similarity: 164/414 - (39%)
• Gaps: 97/414 - (23%)

  Fly     7 ILLLIFYISYLMFGAAIYYHIEHGEEKISRAEQRK-AQIAINEYL--LEELGDKNTTTQ---DEI 65
            :.|::...:|.:.||.|:|.:|...|::.:.:|.| .....||::  |..|...|.|.:   :.:
 Worm   166 VALVLLTCTYTVIGALIFYSVEQPHEQMMKEQQLKLIYTRQNEFVDDLIRLAAGNETKRYEWESL 230

  Fly    66 LQR-ISDYCDKPVTLPPTY---------DDTPYTWTFYHAFFFAFTVCSTVGYGNISPTTFAGRM 120
            .:| :.:..|:.......|         :....||||..:.|||.||.:|:||||..|.|..||:
 Worm   231 AERHMHNMSDQLFVAFEKYFLTSNEVKKNAATETWTFSSSIFFAVTVVTTIGYGNPVPVTNIGRI 295

  Fly   121 IMIAYSVIGIPVNGILFAGLGEYFGRTFEAIYRRYKKYK-----------------------MST 162
            ..|.:|::|||:..:..|.||::.......:|..|.|.|                       |..
 Worm   296 WCILFSLLGIPLTLVTIADLGKFLSEHLVWLYGNYLKLKYLILSRHRKERREHVCEHCHSHGMGH 360

  Fly   163 DMHY----VPPQLGLITTVVIALIPGIALFLLLPSWVFTYFENWPYSISLYYSYVTTTTIGFGDY 223
            ||:.    :|..|.|...:|.....|:.:..|.|         |.:..|.|:|::|.||:||||.
 Worm   361 DMNIEEKRIPAFLVLAILIVYTAFGGVLMSKLEP---------WSFFTSFYWSFITMTTVGFGDL 416

  Fly   224 VPTFGANQPKEFGGWFVVYQIFVIVWFIFSLGYLVMIMTFITRGLQ-SKKLAYLEQQLSSNLKAT 287
            :       |:..|     |...::::.|..|....|.:..:  |:| .:|:.|..:::.....|
 Worm   417 M-------PRRDG-----YMYIILLYIILGLAITTMCIDLV--GVQYIRKIHYFGRKIQDARSA- 466

  Fly   288 QNRIWSGVTKDVGYLRRMLNELYILKVKFCRKGNRKKPKNKAKTEQKKKSS-------------R 339
                    ...||....:::|||   ....:|..|...:.....|....|.             |
 Worm   467 --------LAVVGGKVVLVSELY---ANLMQKRARNMSREAFIVENLYVSKHIIPFIPTDIRCIR 520

  Fly   340 YI-----AYTLPRSNSCPDLSMYR 358
            ||     |.|:..|:|..|:...|
 Worm   521 YIDQTADAATISTSSSAIDMQSCR 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	83..144	CDD:462301	27/69 (39%)
		Ion_trans_2	185..266	CDD:462301	19/80 (24%)
twk-7	NP_498903.3	Ion_trans_2	<265..321	CDD:462301	25/55 (45%)
		Ion_trans_2	373..>422	CDD:462301	18/64 (28%)