Protein Alignment Ork1 and twk-23

DIOPT Version :10

• Sequence 1: NP_001285097.1
• Gene: Ork1 / 32020
• FlyBaseID: FBgn0017561
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_001257229.1
• Gene: twk-23 / 192071
• WormBaseID: WBGene00006676
• Length: 443
• Species: Caenorhabditis elegans
• Alignment Length: 464
• Identity: 102/464 - (21%)
• Similarity: 183/464 - (39%)
• Gaps: 127/464 - (27%)

  Fly     7 ILLLIFYISYLMFGAAIYYHIEHGEEKISRAEQRKAQIAINEYLLEELGDKNTTTQD--EILQRI 69
            :.|..|.:.|:..||.:::.:| ||.: :....::.:.|:|  |.:::..|..||::  ||.:.:
 Worm    46 LALYCFVVCYVFAGAWVFHQLE-GENE-TELHDKQREYAMN--LKKDVIAKLATTENVAEINEHL 106

  Fly    70 SDYCDKPVTLPPTYDD----------TPYTWTFYHAFFFAFTVCSTVGYGNISPTTFAGRMIMIA 124
            ..:......|..:.|:          .|..|||..:..|:||:.:|:||||::|.|...::.::.
 Worm   107 RMFLRNISNLHISLDNYLIFNEPTQIVPKRWTFPSSVLFSFTILTTIGYGNVTPHTQQCKVFLMI 171

  Fly   125 YSVIGIPVNGILFAGLGEYFGRTFEAIYRRYKK--YKMSTDMHYVPPQLGLITTVV-IALIPGI- 185
            |...|||:..|..|.||.:......|:.::..|  .|..:|.|       |:..:. :.|:.|:
 Worm   172 YGAFGIPLFLITIADLGRFSKTAIMALVQKVSKRELKKQSDEH-------LLREIAEVLLVAGLF 229

  Fly   186 ALFLLLPSWVFTYFEN-WPYSISLYYSYVTTTTIGFGDYVPTFGANQPKEFGGWFVVYQIFVIVW 249
            .:|:.:.|.|...:|| ..|..|:|:||::.||||.||.||.
 Worm   230 VVFIAIGSAVIPLWENQLTYFDSVYFSYMSLTTIGLGDIVPR----------------------- 271

  Fly   250 FIFSLGYLVMIMTFITRGL-----QSKKLA-------YLEQQLSSNLKATQNRIWSG-------- 294
               .:.:|:..:.:||.||     ..::||       |..:|: :|:|..  .:|.|
 Worm   272 ---RMDFLLPTLIYITIGLWLTTALVEQLADVFRLVHYAGRQV-TNVKGI--TVWLGGRRLSMGG 330

  Fly   295 ----VTKDVGYLRRMLNELYILKVKFCRKGNRKKPKNKAKTEQKKKSSRYIAYTLP--------- 346
                |.:.||....::|::...:........:..|                  |||
 Worm   331 LISTVCRRVGMSDNLINQINWDRTVIDALDGKMPP------------------TLPIFPWHFTDF 377

  Fly   347 RSNSCP-----------DLSMYRVEPAPIPSRKRAFSVCADMVAAQREAGMVHANSDTELSKLDR 400
            ..:..|           |.|.|..:|.....::||..:.|..::..|        ...|...||.
 Worm   378 LEHDPPLIDLSIDLDQMDGSFYCSKPLSAKKQRRASQMSAPAISWMR--------PQEEARILDA 434

  Fly   401 EKTFETAEA 409
            :.||...:|
 Worm   435 DGTFPNIDA 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	83..144	CDD:462301	23/70 (33%)
		Ion_trans_2	185..266	CDD:462301	20/82 (24%)
twk-23	NP_001257229.1	Ion_trans_2	<136..190	CDD:462301	21/53 (40%)
		Ion_trans_2	224..302	CDD:462301	27/103 (26%)