Protein Alignment Ork1 and twk-45

DIOPT Version :10

• Sequence 1: NP_001285097.1
• Gene: Ork1 / 32020
• FlyBaseID: FBgn0017561
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_001122742.2
• Gene: twk-45 / 190614
• WormBaseID: WBGene00006695
• Length: 508
• Species: Caenorhabditis elegans
• Alignment Length: 511
• Identity: 108/511 - (21%)
• Similarity: 185/511 - (36%)
• Gaps: 151/511 - (29%)

  Fly     5 RWILLLIFYISYLMFGAAIYYHIEHGEEKISRAEQRKAQIAINEYLLEELGD----KNTTTQDEI 65
            |.|.|:....:|:..|..::..:|...|.....|..|   ::||.:..|..|    ..||..::.
 Worm    85 RHITLISILAAYICLGGFLFQKLESPREIEELQETLK---SMNEIIKNETMDIIKITLTTNGEDR 146

  Fly    66 LQRISDYC-------------------DKPVTLPPTYDDTPYTWTFYHAFFFAFTVCSTVGYGNI 111
            .|::.|..                   .|...|     |....|.|..|.|::.|:.||:|||.|
 Worm   147 NQKLGDLLRAYHRILLETEGKFHGSAWHKSENL-----DMNLMWYFSSATFYSMTLFSTIGYGTI 206

  Fly   112 SPTTFAGRMIMIAYSVIGIPVNGILFAGLGEYFGRTFEAIY----RRYKKY-KMSTDMH----YV 167
            :..||.|:.:.:.|:.||:|:..::...:|.:|.:.....|    .:||.. |.|.::.    .:
 Worm   207 TCQTFWGKTVSMVYASIGLPIMLLVLGDIGVWFQKVMTNAYIFVMLKYKSLRKQSIEIKRKETLL 271

  Fly   168 PPQLG--------LITTVVIALI-------PGIALFLLLPSWVFTYFENWPYSISLYYSYVTTTT 217
            |..|.        :|.|:.|.|.       |||           .:|:      :.|:::::.||
 Worm   272 PMWLAMLVVFTYIIICTLTILLFDDNEGDEPGI-----------NFFD------AFYFTFISLTT 319

  Fly   218 IGFGDYVPTFGANQPKEFGGWFVVYQIFVIVWFIFSLGYLVMIMTFITRGLQSK--KLAY-LEQQ 279
            ||.||.:|            :.:.|..|:.:.|:..|..:.::.|.|...|...  .|.| ||.|
 Worm   320 IGLGDVMP------------YNIQYSPFLPLAFLLGLALISIVNTSIYSTLYQSFYNLIYSLEDQ 372

  Fly   280 LSSNLKATQNRIWSGVTKDVGYLRRMLNELYILKVKFCRKGNRKKPKNKAKTEQKKKSSRYIAYT 344
            |        :||.:...:..||  |:..::                         :.:.:.:..|
 Worm   373 L--------DRIHNSRRRGAGY--RVFQDM-------------------------ESTFQMLVCT 402

  Fly   345 LPRSNSCPDLSMYRVEPAPIPSRKRAFSVCADMV-AAQREAGMVHANSDTELSKLDREKTFETAE 408
            .|              |:|..||.|..|:..|.. .|::|:......:.||         .:..:
 Worm   403 FP--------------PSPAHSRIRFASLIRDSFREAKKESAQPKVRTRTE---------SDIPD 444

  Fly   409 AYRQTTDLLAKVVNALATVKPPPAEQEDAALYGGYHGFSDSQILASEWSFSTVNEF 464
            .::|   .:||....|.:......|:..|...|...||..|  |....:.||.:.|
 Worm   445 GFQQ---WMAKRSRRLHSADDEMKEKRRAPTLGALGGFDMS--LFKPRNRSTTSPF 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	83..144	CDD:462301	20/60 (33%)
		Ion_trans_2	185..266	CDD:462301	16/80 (20%)
twk-45	NP_001122742.2	Ion_trans_2	179..241	CDD:462301	22/66 (33%)
		Ion_trans_2	278..354	CDD:462301	21/104 (20%)