DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ork1 and twk-49

DIOPT Version :9

Sequence 1:	NP_001285097.1	Gene:	Ork1 / 32020	FlyBaseID:	FBgn0017561	Length:	1019	Species:	Drosophila melanogaster
Sequence 2:	NP_001022268.1	Gene:	twk-49 / 187626	WormBaseID:	WBGene00019904	Length:	337	Species:	Caenorhabditis elegans

Alignment Length:	151	Identity:	36/151 - (23%)
Similarity:	72/151 - (47%)	Gaps:	24/151 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SP--NRW--ILLLIFYISYLMFGAAIYYHIEHGEEKIS--------RAEQRKAQIAINEYLLEE- 53
            ||  .||  :||::....:::|||..:|..|....:::        ..|:|:....|:..:..:
Worm    40 SPCFQRWSPVLLILLTTVFILFGATCFYLFERDPHEMTVRKWYMNLAVERRQFARTISSRIFNDT 104

  Fly    54 -----LGDKNTT--TQDEILQRISDYCDKPVTLPPTYDDTPYTWTFYHAFFFAFTVCSTVGYGNI 111
                 :.|:..|  .|..:::.:..|.||...:||:..:    |::..:|.||:::..|:|.|..
Worm   105 RNLLIIIDREQTERVQQLLVESLKRYEDKLTIVPPSRRE----WSWISSFNFAYSLLLTIGGGFK 165

  Fly   112 SPTTFAGRMIMIAYSVIGIPV 132
            .|.|...::..:.|.:||||:
Worm   166 VPATVGSQIFAVFYCLIGIPL 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	<90..144	CDD:285168	14/43 (33%)
Ork1	NP_001285097.1	Ion_trans_2	185..269	CDD:285168
twk-49	NP_001022268.1	Ion_trans_2	<144..191	CDD:369572	14/43 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010