Protein Alignment Ork1 and twk-30

DIOPT Version :9

• Sequence 1: NP_001285097.1
• Gene: Ork1 / 32020
• FlyBaseID: FBgn0017561
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_492381.3
• Gene: twk-30 / 185335
• WormBaseID: WBGene00006682
• Length: 608
• Species: Caenorhabditis elegans
• Alignment Length: 554
• Identity: 127/554 - (22%)
• Similarity: 226/554 - (40%)
• Gaps: 134/554 - (24%)

  Fly     7 ILLLIFYISYLMFGAAIYYHIEHGEEKISRAEQRKAQIAIN--EYL-------------LEELGD 56
            :||:...:.|::.||.::..:| ||...:..:...|:|..|  :|:             .:.:.|
 Worm     9 VLLIGSVVLYIILGAIVFQMLE-GEHLDALKKDHMAKIEQNAKDYVDKLWSVAKRDRDKYKNVED 72

  Fly    57 KNTTTQDEILQRISDYCDKPV----TLPPTYDDTPYTWTFYHAFFFAFTVCSTVGYGNISPTTFA 117
            ...:.:::.:...:||.|...    .:...||:...||.|.::.||..|:.:::|||.::|:||.
 Worm    73 LIKSVKEDTVDDFNDYVDTVFYAHRAVRHGYDEDSPTWDFANSVFFTTTMLTSIGYGYVAPSTFG 137

  Fly   118 GRMIMIAYSVIGIPVNGILFAGLGEYFGRTFEAI----------YRRYKKYKMSTDMHYVPPQLG 172
            ||:..:.|.:||||:..:..|.:.::...|...:          ::|.:|.::..|.  :.|..|
 Worm   138 GRLFGVIYCLIGIPLTLVTVANVAKFLSETIFFLHYELWNKCLEWKRKRKGEVEADP--LQPMFG 200

  Fly   173 -------LITTVVIALIPGIALFLL------LPSWVFTYFENWPYSISLYYSYVTTTTIGFGDYV 224
                   ::..|.:...|.:.:|..      :.:||..|:|.|.|..|||:.:::..|:||||..
 Worm   201 DDENEEEILDRVRLVRFPPLTVFFFVFVYGCIAAWVVRYWETWTYVESLYFIFISILTVGFGDIR 265

  Fly   225 PTFGANQPKEFGGWFVVYQIFVIVWFIFSLGYLVMIMTFITRGLQSKKLAYLEQQLSSN------ 283
            |:.|       ..|  |...||:|..|.:    .|.|..:.| :..|::.||.::|.|:
 Worm   266 PSPG-------NIW--VTLAFVVVGVILT----TMCMDVVGR-MYLKEIHYLGRKLKSSNPFYLL 316

  Fly   284 --LKATQNR-----IWSGVTKDVGYLRRMLNELYILKVKFCRKGNRKKPKNKAKTEQKKKSSRYI 341
              .||.:.|     :.:.:.|.:.:..:..|||       .||.:::| |.|.:......:.:::
 Worm   317 REAKARRRRAAMASLLAQLAKGMIFAHKDYNEL-------ARKKSKRK-KEKRRGSHVLPNEKFM 373

  Fly   342 AYTLPRSNSCPD---------LSMYRVEPAPIPSRKRAFSVCADMV------------AAQREAG 385
            ...||     ||         .|.|.|..|..|    .||...|:.            |..||..
 Worm   374 FARLP-----PDPPSDCQVVSTSAYSVRLAWAP----PFSPDPDLTYNIRYRLKHNEDAKVRELR 429

  Fly   386 MVHANSDTELSKLD-----------REKTFETAEAYR-QTTD-------LLAKVVNALA---TVK 428
            .:..|: .|:..:|           ..|..|:...|. |.|:       :||..:||..   |.:
 Worm   430 GIKGNT-VEIMSVDSCSLYEFRITAHNKFGESKAVYLVQYTEPQLSPQHILATRLNANTIELTWE 493

  Fly   429 PPPAEQEDAALYGGYHGFSDSQILASEWSFSTVN 462
            ||..:..:...|..|...:.:..| |||....||
 Worm   494 PPYKKSHEVKNYVVYFTENPNASL-SEWEKIPVN 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	<90..144	CDD:285168	19/53 (36%)
		Ion_trans_2	185..269	CDD:285168	26/89 (29%)
twk-30	NP_492381.3	Ion_trans_2	103..166	CDD:285168	22/62 (35%)
		Ion_trans_2	224..298	CDD:285168	25/87 (29%)
		FN3	379..469	CDD:238020	20/94 (21%)
		FN3	475..565	CDD:238020	15/53 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810