Protein Alignment Ork1 and twk-35

DIOPT Version :10

• Sequence 1: NP_001285097.1
• Gene: Ork1 / 32020
• FlyBaseID: FBgn0017561
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_508031.3
• Gene: twk-35 / 185149
• WormBaseID: WBGene00006687
• Length: 557
• Species: Caenorhabditis elegans
• Alignment Length: 496
• Identity: 98/496 - (19%)
• Similarity: 183/496 - (36%)
• Gaps: 162/496 - (32%)

  Fly     8 LLLIFYISYLMFGAAIYYHIE------------HGEE--KISRAEQRKAQIAIN-EYLLEELGDK 57
            :|:|.::.|.:.|..:::.||            |..|  :.:|.:....:|..| :||:...|:.
 Worm   145 VLIIVFLIYCISGGLVFWLIEEPYQSELRDAWQHKIENNRTARVDAMMKKIFNNSDYLIYIKGNT 209

  Fly    58 NTTTQDEILQRISDYCDKPVTLPPTYDDTPYTWTFYHAFFFAFTVCSTVGYGNISPTTFAGRMIM 122
            :.......::.:..|.::   |...:......|.|::|..||.|:|:|:|||:|.|.|.||||:.
 Worm   210 SQRLTTFFIEELGSYENQ---LGVKWSQQKMDWDFWNAVLFAGTICTTIGYGHIYPMTDAGRMLT 271

  Fly   123 IAYSVIGIPVNGILFAGLGEYFGRTF-------EAIYRRY----------------KKYKMSTDM 164
            :.:::.|||:..::....|:....|.       :.:.||.                ::.:...|:
 Worm   272 MIFALFGIPLMLLVLQDFGKLLTITMKFPWFQTKRLMRRIMRCCTKQPIEEMKEIERQERHDLDI 336

  Fly   165 HYVPPQLGLITTVVIALIPGIALFLLLPSWVF-------TYFENWPYSISLYYSYVTTTTIGFGD 222
            ..:|            |..||||.:   :|:|       .:..||....|.|:.:.:.:|:|.||
 Worm   337 FDLP------------LPVGIALIV---TWIFICSFVLSVWDHNWTLLESFYFFFTSLSTVGLGD 386

  Fly   223 YVPTFGANQPKEFGGWFVVYQIFVIVWFIFSLGYLVMIMTFITRGLQ--SKKLAYLEQQLSSNLK 285
            .||    :.|:                      .|:.:..||..||.  |..:..|:.::.|..:
 Worm   387 LVP----SSPR----------------------LLITMFGFILVGLSLVSMVINLLQAKMKSTYE 425

  Fly   286 ATQN-----RIWSGVTKDVGYLRRMLNELYILKVKFCRKGNRKKPKNKAKTEQKKKSSRYIAYTL 345
            |.:|     .|...:...:|.|:..                  .|..:.||:..::|       |
 Worm   426 AGRNDEKTPHIHQTLPTSLGVLQCF------------------SPDEEKKTDYSERS-------L 465

  Fly   346 PRSNSCPDLSMYRVEPAPIPSRKRAFSVCADMVAAQREAGMVHANSDT--------ELSKL---- 398
            .||.. ..||:..|....:                 |..|:...|:||        |::.|
 Worm   466 SRSTQ-TSLSLPGVRQVVL-----------------RSDGVHWVNTDTSSPTKSPDEVTNLVEYE 512

  Fly   399 -----------DREKTFETAEAYRQTTDLLAKVVNALATVK 428
                       :..:.|..||:....|::|.:|...|:.::
 Worm   513 TALRVCEQIGDNNNEEFSEAESLICETEVLLEVGECLSDLE 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	83..144	CDD:462301	22/60 (37%)
		Ion_trans_2	185..266	CDD:462301	19/87 (22%)
twk-35	NP_508031.3	Ion_trans_2	230..294	CDD:462301	22/63 (35%)
		Ion_trans_2	345..420	CDD:462301	23/103 (22%)