DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ork1 and twk-39

DIOPT Version :9

Sequence 1:	NP_001285097.1	Gene:	Ork1 / 32020	FlyBaseID:	FBgn0017561	Length:	1019	Species:	Drosophila melanogaster
Sequence 2:	NP_001076639.1	Gene:	twk-39 / 182864	WormBaseID:	WBGene00006690	Length:	676	Species:	Caenorhabditis elegans

Alignment Length:	187	Identity:	45/187 - (24%)
Similarity:	83/187 - (44%)	Gaps:	36/187 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LIFYIS-YLMFGAAIYYHIEHGEEKISRAEQRKAQIAINEYLLEELGDKN----TTTQDEILQRI 69
            |.|.:: |.:.||.::..:|:..|...:.:.:.|.:.:.:.:...:..||    |..::|....:
Worm    29 LCFLVALYAVAGAFMFQAVEYPYELGLQGKVKNASLKVVDDIYRFINRKNVIEETAVKNESQWAL 93

  Fly    70 SDY------------CDKPVTLPPTYDDTPYTWTFYHAFFFAFTVCSTVGYGNISPTTFAGRMIM 122
            .::            .|:.....||:.     |||..|..::.||.:|:|||:|.|.|..||::.
Worm    94 KEFEMLLVHAMNFEGYDEHDEERPTFQ-----WTFSGALLYSITVFTTIGYGHICPKTDTGRLLT 153

  Fly   123 IAYSVIGIPVNGILFAGLGEYFGRTFEAIY--------------RRYKKYKMSTDMH 165
            |.||::|||:..:..|.:.|...:.|..||              ||.::..:|...|
Worm   154 ILYSILGIPLMLLCLANIAETLAQVFTYIYFKLCCAYCRWQKNRRRVRRAALSFRYH 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	<90..144	CDD:285168	23/53 (43%)
Ork1	NP_001285097.1	Ion_trans_2	185..269	CDD:285168
twk-39	NP_001076639.1	Ion_trans_2	<120..177	CDD:285168	23/61 (38%)
twk-39	NP_001076639.1	Ion_trans_2	498..580	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D774951at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020