Protein Alignment Ork1 and twk-20

DIOPT Version :10

• Sequence 1: NP_001285097.1
• Gene: Ork1 / 32020
• FlyBaseID: FBgn0017561
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_510284.1
• Gene: twk-20 / 181485
• WormBaseID: WBGene00006673
• Length: 364
• Species: Caenorhabditis elegans
• Alignment Length: 414
• Identity: 95/414 - (22%)
• Similarity: 165/414 - (39%)
• Gaps: 120/414 - (28%)

  Fly     5 RWILLLIFYISYLMFGAAIYYHIEHGEEKISRAEQRKAQIAINEYLLEELGDKNTTTQDEILQRI 69
            |.:||::...:||:|||.::..:|                          .:|:|..:||| :||
 Worm    10 RALLLILSTFTYLLFGAMVFDKLE--------------------------SEKDTWVRDEI-ERI 47

  Fly    70 SD-------------YCDKPVTLPPTYDDTPYTWTFYHAFFFAFTVCSTVGYGNISPTTFAGRMI 121
            :|             :..:.:.:........|.|.|..||:||..|.:|||||:.:|:|.||::.
 Worm    48 TDRLKHKYNFSERDLHLFEAIAIKSIPQQAGYQWQFAGAFYFATVVITTVGYGHSAPSTNAGKLF 112

  Fly   122 MIAYSVIGIPVNGILFAGLGEYFGRTFEAIYRRYKKYKMSTDMHY--------VPPQLGLITTVV 178
            .:.:::.|:|:..|:|..:||.. .||.|    |..:|....:|.        |.|...|:.::.
 Worm   113 CMIFALFGVPMGLIMFQSIGERV-NTFIA----YSLHKFRDSLHQQGFTCLQEVTPTHLLMVSLT 172

  Fly   179 IALIPGIALFLLLPS--WVFTYFENWPYSISLYYSYVTTTTIGFGDYVPTFGAN----QPKEFGG 237
            |.       |:::.|  ::|...|.|....:.|:..:|.:||||||.||....|    ||
 Worm   173 IG-------FMVIVSGTYMFHTIEKWSIFDAYYFCMITFSTIGFGDLVPLQQVNALQDQP----- 225

  Fly   238 WFVVYQIFVIVWFI------FS-------LGYLVMIMTFITRGLQSKKLAYLEQQLSSN------ 283
               :| :|..:.||      ||       ||::......:|...:....|.:.::.:.|
 Worm   226 ---LY-VFATIMFILIGLAVFSACVNLLVLGFMASNADEVTAAQREPPSAIVLERFTRNSLVDSQ 286

  Fly   284 ------------LKATQNRIWSGV---TKDVGYLRRMLNELYILKVKFCRKGNRKKPKNKAKTEQ 333
                        |.....|::|.|   |.|| :|||......|.....|.....:.|:::....:
 Worm   287 IFNIQKHSTVGVLPGRPRRMYSIVPNSTADV-HLRRRSTRRSIQDTVCCGCFKPRPPRHRFSLTR 350

  Fly   334 KKKSSRYIAYTLPRSNSCPDLSMY 357
            :..:..::.          ||.:|
 Worm   351 RPTNISHLV----------DLELY 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	83..144	CDD:462301	23/60 (38%)
		Ion_trans_2	185..266	CDD:462301	26/99 (26%)
twk-20	NP_510284.1	Ion_trans_2	<78..135	CDD:462301	23/56 (41%)
		Ion_trans_2	175..250	CDD:462301	24/83 (29%)