Protein Alignment Ork1 and twk-44

DIOPT Version :9

• Sequence 1: NP_001285097.1
• Gene: Ork1 / 32020
• FlyBaseID: FBgn0017561
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_509942.4
• Gene: twk-44 / 181349
• WormBaseID: WBGene00006694
• Length: 733
• Species: Caenorhabditis elegans
• Alignment Length: 641
• Identity: 125/641 - (19%)
• Similarity: 218/641 - (34%)
• Gaps: 236/641 - (36%)

  Fly     6 WILLLIFYISYLMFGAAIYYHIEHGEEKISRAEQRKAQIAINEYLLEELGDKNTTTQDEILQRIS 70
            :::.:|..|:|.:.|..|::.||...|:|..|::|....|:.:.|:|.|        .:|..|:.
 Worm    69 YLVPIILLIAYSVLGGLIFWSIERPNEEIMLADKRNYIAALTDDLVEVL--------MQIHNRLI 125

  Fly    71 DY--------------------------------------------CDKPVTLPP---------- 81
            |:                                            ..|.|.|.|
 Worm   126 DFNRVYSNNTYLLMIHYRGYRKFALNQIHKSVYWYTLSTFYLTEHEMHKVVALRPKNPEQLWKRH 190

  Fly    82 ------------------------------------------------TYDD--------TPYTW 90
                                                            .|::        || .|
 Worm   191 FESNFGRIRALKNYTEQLCLRCWELGVEGANQGWTRYNYSLMVNQSVEEYNNSVGLGHVLTP-VW 254

  Fly    91 TFYHAFFFAFTVCSTVGYGNISPTTFAGRMIMIAYSVIGIPVNGILFAGLGEYF----GRTFEAI 151
            ||::|.|.|.|..:|:|||||:..|..|::..:.|:|:|||:..::....|..|    ...::.|
 Worm   255 TFWNAMFLAVTTYTTIGYGNITAKTKLGKLAAMVYAVVGIPLVLMILHKSGRLFLMGLEHMWDFI 319

  Fly   152 YRRYKKYKMSTDMHYVPPQLG--LITTVVIALIPGIAL-FLLLPSWVFTYFE-NWPYSISLYYSY 212
            .|....:.:.:....| ...|  .|:.:.:.|..|:|. ::.|.:.:|..|| :|.|..|.|:.:
 Worm   320 LRITDSFCVGSGKQRV-RNTGEDRISEMPLILAIGVAFGWMFLCAAIFLRFEKDWDYFKSFYFFF 383

  Fly   213 VTTTTIGFGDYVPTFGANQPKEFGGWFVVYQIFVIVWFIFSLGYLVMIMTFITRGLQ---SKKLA 274
            .:.||||:||..||...:.       |:::.:.:|     .|..:.|.:..|...|:   .:.|.
 Worm   384 CSLTTIGYGDVTPTNSEDM-------FIIFGLIII-----GLSLVSMCINVIQLKLEKLFEELLL 436

  Fly   275 YLEQQLSSNLKATQ--------NRIWSGVTKDVGYLRRML-------------NELYILKVKFCR 318
            .|.::|:::...|:        ..:|....|..|.|:..|             :|.::..:.|.|
 Worm   437 TLMEELNADPDGTRLKAGTIGAREMWRAWKKRRGKLKDGLERAKGARDVANKASENFVKMLPFSR 501

  Fly   319 KGNRKK--PKNKAKTEQKKKSSR--------YIAYTLP----------RSNSCPDLSMYR---VE 360
            |..|:.  .:.:.|...|:||::        ..|||..          ||:...|.|.:.   :.
 Worm   502 KRERQNLIAEFQKKLHSKEKSTQTDFGYPRCEEAYTETSDVDSCVTDFRSSIISDKSQHHLLLIP 566

  Fly   361 PAPI--PSRKRAFSVCADM-VAAQREAGMVHANSDTELSKLDREKTFETAEAYRQTTDLL----- 417
            ..||  |||      |... |.|..||.:..::|....|         ...::|.::.:|
 Worm   567 DGPICGPSR------CESRPVVAMAEASLCSSSSVNPSS---------YPSSHRPSSSILSSSPG 616

  Fly   418 -----------AKVVNALATVKPPPAEQEDAALYGGYHGFSDSQILASEWSFSTVN 462
                       ||...|.:..:.||....|.               :..|:|...|
 Worm   617 SRISAPSAASSAKSAPAASPSRQPPLVDFDP---------------SRRWTFVATN 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	<90..144	CDD:285168	21/53 (40%)
		Ion_trans_2	185..269	CDD:285168	22/85 (26%)
twk-44	NP_509942.4	Ion_trans_2	237..308	CDD:285168	24/71 (34%)
		Ion_trans_2	354..>397	CDD:285168	15/42 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810