Protein Alignment Ork1 and twk-24

DIOPT Version :10

• Sequence 1: NP_001285097.1
• Gene: Ork1 / 32020
• FlyBaseID: FBgn0017561
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_001367093.1
• Gene: twk-24 / 179682
• WormBaseID: WBGene00006677
• Length: 579
• Species: Caenorhabditis elegans
• Alignment Length: 520
• Identity: 103/520 - (19%)
• Similarity: 184/520 - (35%)
• Gaps: 159/520 - (30%)

  Fly     5 RWILLLIFYISYLMFGAAIYYHIEHGEEK---ISRAEQRKAQIAINEYLLEELGDKNTTTQDEIL 66
            |.|..|:...|:.:||..|:..||.|.|.   |.:.|..|           ::.::....|:::.
 Worm   116 RHIAWLVVLFSFSLFGGVIFSAIEGGYETTQLIKKFEHEK-----------DVYERRKIYQEQLF 169

  Fly    67 QRISD-----------------------------YCDK-PVTL-PPTYDDTPYTWTFYHAFFFAF 100
            ||:.:                             |..| .||: .|...:|  .|..:...:::.
 Worm   170 QRLREIEHDNTNPRGRNSSREHFKLEQSRHALEWYEQKMGVTIEEPQMRET--KWNLWGGVYYSA 232

  Fly   101 TVCSTVGYGNISPTTFAGRMIMIAYSVIGIPVN-------GILFAGLGEY----FGRTF--EAIY 152
            ::.:|:||||..|.|.:||:|.:.|:.||||:.       |.|:....||    |...|  :::.
 Worm   233 SLYTTIGYGNFHPLTKSGRIISMMYACIGIPLVFTILLDWGFLYFTWIEYGWNRFNENFCQKSLQ 297

  Fly   153 R---------RYKKYKMSTDMHYVPPQLGLITT---------------------------VVIAL 181
            |         |.::......:....|.|...||                           |....
 Worm   298 RDMQRRIRRERIRRVGSELSLSSTAPLLHRTTTQLSNPVQHIESNHPLSPLDVDVPMGEQVQTVP 362

  Fly   182 IPGIALF----LLLPSWVFTYFE-NWPYSISLYYSYVTTTTIGFGDYVPTFGANQPKEFGGWFVV 241
            |...|:|    :::.:::...:| .|.|..:.|:.:.:.||||.||.|    ...|.     |::
 Worm   363 IKSAAIFFFLWIMISAFIVRLWEYEWTYFTAFYFFFTSLTTIGLGDVV----TKTPN-----FII 418

  Fly   242 YQIFVIVWFIFSLGYLVMIM-----TFITRGLQSKKLAYLEQQLSSNLKATQNRIWSGVTKDVGY 301
            :.:.:.:..:..:|....|:     ....|.|:|....|..:|:..:: ||.:.:   ..::.|.
 Worm   419 FNLAMTLIGLSVVGLCAAIVQAKVKLVFDRMLRSIDAQYRIRQVDPHV-ATMSIV---EDEEEGV 479

  Fly   302 LRRMLNELYILKVKFCRKGNRKKPKNKAKTEQKKKSSRYIAYTLPRSNSCPDLSMYRVEPAPIPS 366
            .|.:.::....::.|......||...|.:.:||......|..|                   .||
 Worm   480 KRLIQSQSLEDRIIFLFVDEHKKSMLKERWKQKSTMVNRITQT-------------------YPS 525

  Fly   367 RKRAFSVCADMVAAQREAGMVHANSDTELSKLDREKTFETAEAYRQTTDLLAKVVNALATVKPPP 431
            :...:......|..||:      .||.:||..|.|..        :..:|..|::       |||
 Worm   526 KADKYVQTGQRVYDQRQ------GSDEDLSDEDEEDV--------EYDELGNKII-------PPP 569

  Fly   432  431
             Worm   570  569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	83..144	CDD:462301	21/71 (30%)
		Ion_trans_2	185..266	CDD:462301	17/90 (19%)
twk-24	NP_001367093.1	Ion_trans_2	<221..273	CDD:462301	16/51 (31%)