Protein Alignment Ork1 and egl-23

DIOPT Version :9

• Sequence 1: NP_001285097.1
• Gene: Ork1 / 32020
• FlyBaseID: FBgn0017561
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_001255775.1
• Gene: egl-23 / 178358
• WormBaseID: WBGene00001190
• Length: 726
• Species: Caenorhabditis elegans
• Alignment Length: 714
• Identity: 142/714 - (19%)
• Similarity: 246/714 - (34%)
• Gaps: 259/714 - (36%)

  Fly    28 EHGEEKISRAEQRKAQI----------------------AINEYLLEELG-------DKNT---- 59
            :|..||:||.::..|.|                      .::|.|::.|.       :.||
 Worm   132 DHLSEKLSREKRAAAHIMRSRKCVISVIKKMSSMECSFDTLDEKLVKALDECYHVAVEHNTHVNH 196

  Fly    60 ---TTQDEILQRISDYCDKPVTLPPTYDDTPYTWTFYHAFFFAFTVCSTVGYGNISPTTFAGRMI 121
               |...|.::.:.:..::.|:          .|:|..:..|||||.:|:||||::|.||.||:.
 Worm   197 VLFTNSKEEVESVGEEAEEDVS----------EWSFMDSLLFAFTVITTIGYGNVAPRTFGGRLF 251

  Fly   122 MIAYSVIGIPVNGILFAGLGEYFGRTF-EA---IYRRYKKYKMSTDMHYV--------------- 167
            :|.|.:||||...:..|.||::..... ||   ..:.:||.|.:.:.:::
 Worm   252 VIGYGLIGIPFTLLAIADLGKFISEMMVEAKSFCRKTWKKLKKAWNPNFIRAKDLSNTDIEEKIL 316

  Fly   168 -------PPQLGLI------------TTVVIALIPGIAL--FLLLPSWVFTYFENWPYSISLYYS 211
                   .|:...:            |::.|..:..||.  |:|.     .|..:..:..::|::
 Worm   317 DNEKIENEPETSEVSEEEDDLTETEATSLFILFLVYIAFGGFMLA-----AYEPDMDFFKAVYFN 376

  Fly   212 YVTTTTIGFGDYVPTFGANQPKEFGGWFVVYQIFVIVWFIFSLGYLVMIMTFITRGLQSKKLAYL 276
            :||.|:||.||.||.            ...|.:..||:....|....:.:......|  |||.|.
 Worm   377 FVTLTSIGLGDIVPR------------SETYMLITIVYIAIGLALTTIAIEIAADAL--KKLHYF 427

  Fly   277 EQQLSS--NLKATQNRIWSG--------VTKDVG-------YLRRMLNELYIL---------KVK 315
            .:::.:  |:     .||.|        :.|::|       .:.:.||..:.:         :::
 Worm   428 GRKIENVGNV-----AIWFGGKKITMKALVKNLGDQFNLPTTVVKNLNLDHFVDQAIKVEEGEIE 487

  Fly   316 FCRKGNRKKPKNKAKTE-QKKKSSRYIAYTLPRSNSCPDLSMYR------VEPAPIPSRKRAFSV 373
            ..|....:.|.::.:.| ..:....:|....|.....|. .:||      |.|.|:||
 Worm   488 TLRPPPYEPPSDRFEAEFADEPECEWIRDPTPTPPPSPQ-PVYRLPSPKPVTPEPLPS------- 544

  Fly   374 CADMVAAQREAGMVHANSDTELSKLDREKTFETAEAYRQTTDLLAKVVNALATVKPPPAEQEDAA 438
                                                 ...||:      :||...|.|.|.:|
 Worm   545 -------------------------------------PTITDV------SLAIATPSPEESDD-- 564

  Fly   439 LYGGYHGFSDSQILASEWSFSTVNEFTSPRRPRARACSDFNLE----------APRWQSERPL-- 491
                     |.:::......|.|.|.|.|..||.....:...|          .|.....|||
 Worm   565 ---------DQELILPSPEPSPVREPTPPPPPREPTPREPTPEPEPVREPTPPPPPPAKPRPLTA 620

  Fly   492 -------RSSHNEWTWSGDNQQIQEAFNQ--RYKGQQRA---NGAANSTMVHLEPDALEEQLKKQ 544
                   |.:::|..|    ::.||...|  :::..|:.   :||:.|.....:|.....:
 Worm   621 AEIAAQKRKAYSEEAW----RRYQEYQKQWKKFRQTQKTPAPSGASTSGASTSKPSGTSPE---- 677

  Fly   545 SPGAGRVKKFSMPDGLRRLFPFQKKRPSQDLERKLSVVSVPEGVISQQARSPLDYYSNTVTAAS 608
             .|||      :..|           ||   .|..|:.||..|..|:.| :|....|:.::.:|
 Worm   678 -SGAG------VCTG-----------PS---TRSQSITSVASGKTSRSA-TPESKKSSHLSGSS 719

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	<90..144	CDD:285168	26/53 (49%)
		Ion_trans_2	185..269	CDD:285168	19/85 (22%)
egl-23	NP_001255775.1	Ion_trans_2	216..276	CDD:285168	27/69 (39%)
		Ion_trans_2	347..423	CDD:285168	21/94 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163834
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940