Protein Alignment Ork1 and Kcna4

DIOPT Version :10

• Sequence 1: NP_001285097.1
• Gene: Ork1 / 32020
• FlyBaseID: FBgn0017561
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_067250.2
• Gene: Kcna4 / 16492
• MGIID: 96661
• Length: 654
• Species: Mus musculus
• Alignment Length: 177
• Identity: 35/177 - (19%)
• Similarity: 60/177 - (33%)
• Gaps: 75/177 - (42%)

  Fly     7 ILLLIFYISYLMFGAAIYYHIEHGEEKISRAEQRKAQIAINEYLLEELGDKNTTTQDEILQRISD 71
            :|:...:|..::|.:|:|:           ||                .|:.||.    .|.|.|
Mouse   481 LLIFFLFIGVILFSSAVYF-----------AE----------------ADEPTTH----FQSIPD 514

  Fly    72 YCDKPVTLPPTYDDTPYTWTFYHAFFFAFTVCSTVGYGNISPTTFAGRMIMIAYSVIGI-----P 131
                                   ||::|....:|||||::.|.|..|:::....::.|:     |
Mouse   515 -----------------------AFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALP 556

  Fly   132 VNGILFAGLGEYFGRTFEAIYRRYKKYKMSTDM-------HYVPPQL 171
            |..|:         ..|...|.|..:.:..|.:       .|:|..|
Mouse   557 VPVIV---------SNFNYFYHRETENEEQTQLTQNAVSCPYLPSNL 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	83..144	CDD:462301	15/65 (23%)
		Ion_trans_2	185..266	CDD:462301
Kcna4	NP_067250.2	K_channel_TID	1..>37	CDD:429748
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..145
		BTB_POZ	177..304	CDD:453885
		Ion_trans	307..571	CDD:459842	30/152 (20%)
		S4-S5 linker. /evidence=ECO:0000250|UniProtKB:P63142	463..476
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	525..530		4/4 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	630..654
		PDZ-binding. /evidence=ECO:0000250|UniProtKB:P15385	652..654