Protein Alignment Ork1 and kcnk2

DIOPT Version :10

• Sequence 1: NP_001285097.1
• Gene: Ork1 / 32020
• FlyBaseID: FBgn0017561
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: XP_031758740.1
• Gene: kcnk2 / 100495685
• XenbaseID: XB-GENE-952207
• Length: 412
• Species: Xenopus tropicalis
• Alignment Length: 414
• Identity: 109/414 - (26%)
• Similarity: 186/414 - (44%)
• Gaps: 91/414 - (21%)

  Fly     1 MSPNRW-----ILLLIFYISYLMFGAAIYYHIEHGEEKISRAEQRKAQIAINEYLLEELGDKNTT 60
            |:..:|     :.|::  :.||:.||.::..:|...|.   |::....|..|.::|.. ...|.|
 Frog    40 MNVMKWKTVSTVFLVV--VLYLIIGATVFKALEQPHES---AQRTTIVIQKNNFILNH-SCVNVT 98

  Fly    61 TQDEILQRISDYCDKPVTLPPTYDDTPYT---WTFYHAFFFAFTVCSTVGYGNISPTTFAGRMIM 122
            ..||::|::....:..: :|  ..:|.:.   |....:||||.||.:|:|:|||||.|..|::..
 Frog    99 ELDELIQQLMAAINAGI-IP--IGNTSHQNSHWDLGSSFFFAGTVITTIGFGNISPRTKGGKIFC 160

  Fly   123 IAYSVIGIPVNGILFAG----LGEYFGRTFEAIYRRYKKYKMSTDMHYVPPQLGLITTVVIALIP 183
            |.|:::|||:.|.|.||    ||..||:....:...::|:.:|      ..::.:|:||:..|.
 Frog   161 IIYALLGIPLFGFLLAGVGDQLGTIFGKGIARVEDMFEKWNVS------QTKIRIISTVIFILF- 218

  Fly   184 GIALFLLLPSWVFTYFENWPYSISLYYSYVTTTTIGFGDYVPTFGANQPKEFGGWFVVYQIFV-- 246
            |..||:.:|:.:|.:.|:|....:.|:..:|.|||||||||.          ||..:.|..|.
 Frog   219 GCILFVAIPAVIFQHIEDWHTLDAFYFVVITLTTIGFGDYVA----------GGSDIEYLDFYKP 273

  Fly   247 IVWF--IFSLGYLVMIMTFITRGLQ--SKKLAYLEQQLSSNLKATQNRIWSGVTKDVGYLRRMLN 307
            :|||  :..|.|...:::.|:..|:  |:|    .::.....:|......:.||.:....||.|:
 Frog   274 VVWFWILVGLAYFAAVLSMISDWLRVISRK----TKEEVGEFRAHAAEWTANVTAEFKETRRRLS 334

  Fly   308 -ELYILKVKFCRKGNRKKPKNKAKTEQKKKSSRYIAYTLPRSNSCPDLSMYRVEPAPIPSRKRAF 371
             |:|              .|.:..|..|:|.|..:|.|   ||
 Frog   335 VEIY--------------DKFQRATSIKRKLSAELAMT---SN---------------------- 360

  Fly   372 SVCADMVAAQREAGMVHANSDTEL 395
               .:|...:|...:.|.::|.||
 Frog   361 ---PEMTPCKRTLSVNHLSNDKEL 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	83..144	CDD:462301	28/67 (42%)
		Ion_trans_2	185..266	CDD:462301	27/84 (32%)
kcnk2	XP_031758740.1	Ion_trans_2	<124..182	CDD:462301	25/57 (44%)
		Ion_trans_2	220..298	CDD:462301	27/87 (31%)