DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ork1 and kcnk15

DIOPT Version :9

Sequence 1:	NP_001285097.1	Gene:	Ork1 / 32020	FlyBaseID:	FBgn0017561	Length:	1019	Species:	Drosophila melanogaster
Sequence 2:	XP_005161945.1	Gene:	kcnk15 / 100000132	ZFINID:	ZDB-GENE-080220-30	Length:	357	Species:	Danio rerio

Alignment Length:	397	Identity:	94/397 - (23%)
Similarity:	166/397 - (41%)	Gaps:	100/397 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RWILLLIFYISYLMFGAAIYYHIEHGEEKI-------SRAE-QRKAQIAINEYLLEELGDKNTTT 61
            |.:.|::...|||:.|||::..:|...|..       .||| :||.:....:|  :||
Zfish     7 RTLSLILCIFSYLLVGAAVFVALESDTESARKRMLEHKRAELRRKYRFTDGDY--QEL------- 62

  Fly    62 QDEILQRISDYCDKPVTLPPTYDDTPY----TWTFYHAFFFAFTVCSTVGYGNISPTTFAGRMIM 122
             :.:|::..                |:    .|.|..:|:||.||.:|:|||:.:|.|.||::..
Zfish    63 -ERVLRQAE----------------PHRAGTQWRFAGSFYFAITVITTIGYGHAAPGTDAGKLFC 110

  Fly   123 IAYSVIGIPVNGILFAGLGEYFGRTFEAIYRRYKKYKMSTDMHYVPPQLGL----ITTVVIALIP 183
            :.|:.:|||:..::|..|||........:..|.|:            .|||    |:|..:.|:.
Zfish   111 MLYAGLGIPLTLVMFQSLGERMNTGVRFLLSRMKR------------ALGLQRTEISTQNMVLVG 163

  Fly   184 GIALF--LLLPSWVFTYFENWPYSISLYYSYVTTTTIGFGDYV-----PTFGANQPKEFGGWFVV 241
            .::..  |.:.:..|::||:|.:..:.||.::|.|||||||:|     .....|||
Zfish   164 VLSCLGTLCVGAAAFSHFESWTFFHAYYYCFITLTTIGFGDFVALQKKEDLQENQP--------- 219

  Fly   242 YQIFVIVWFIFSLGYL-----VMIMTFITRGLQSKKLAYLEQ-QLSSNLKATQNRIWSGVTKD-- 298
            |.:|..::.:..|..:     ::::.|:|...:.:|....|: ...::|:|:..|......:|
Zfish   220 YVLFSFIYILLGLTVIGAFLNLVVLRFLTLNTEDEKRDAAERASQRASLRASSLRKAPAFRRDSQ 284

  Fly   299 ------------VGYLRRMLNELYILKVKFCRKGNRKKPKNKAKTEQKKKSSRY---IAYTLPRS 348
                        ..:||...:.:::.....||       ...|.......|.|.   .|::.|||
Zfish   285 THSRTNLLSPRPTPHLRWFCSRVHLDHTSACR-------NTCAGCSVSSVSCRIHADTAFSSPRS 342

  Fly   349 NSCPDLS 355
            .....||
Zfish   343 TLSAGLS 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ork1	NP_001285097.1	Ion_trans_2	<90..144	CDD:285168	23/53 (43%)
Ork1	NP_001285097.1	Ion_trans_2	185..269	CDD:285168	24/95 (25%)
kcnk15	XP_005161945.1	Ion_trans_2	<77..132	CDD:285168	23/54 (43%)
kcnk15	XP_005161945.1	Ion_trans_2	167..243	CDD:285168	22/84 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910