Protein Alignment HOXA5 and CG18599

DIOPT Version :10

• Sequence 1: NP_061975.2
• Gene: HOXA5 / 3202
• HGNCID: 5106
• Length: 270
• Species: Homo sapiens
• Sequence 2: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Alignment Length: 308
• Identity: 71/308 - (23%)
• Similarity: 114/308 - (37%)
• Gaps: 81/308 - (26%)

Human    19 YQLHNYGDHSSVSEQFRDSASMH---------SGRYGY------GYNGMDLSVGRSGSGHFGSGE 68
            ||:.:...|..:.:|.:.....|         .|.:.:      |.|..:.|...:.|.|..:..
  Fly    73 YQMEHQQQHHQLQQQQQQQQHHHHQQLHTHHQDGHHPHPPTPTTGNNNNNSSSSSNSSSHNSNSN 137

Human    69 RARSYAASASAAPAEPRYSQPATSTHSP------------------------------------- 96
            .....||:|:.|.:..:..: |.:.||.
  Fly   138 HREQLAAAAATATSHAQLIE-AAAAHSSLDVGKSFTIAAILGLQSQRKDYNNAINLSLHDNNNII 201

Human    97 QPDPLPCSAVAP-SPGSDSHHGGKNSLSNSSGASAD-------AGS------------THISSRE 141
            ..|...|....| :..:::::||.||.:|:|..|.:       ||:            .|.:...
  Fly   202 GDDNNKCYTSNPNNNNNNNNNGGSNSGNNNSSPSVNNFNCDSVAGNGRYLHGGHQHPHPHQAGFA 266

Human   142 GVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYPWMRKLHISHDN--IGGPEGKRARTAYTR 204
            .|..|.||...|..|.:|...|..      ||.|.....::..:..|:  ....:.||.||.:|.
  Fly   267 AVAAAVGAAPSALQSLQQLHQQHH------AQQQATLSFQREKLKSDSHKKSALKNKRVRTIFTP 325

Human   205 YQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 252
            .|...||.||...:|:....|:.:||.|.|:|.|:|:||||||:||:|
  Fly   326 EQLECLEAEFERQQYMVGPERLYLAHTLKLTEAQVKVWFQNRRIKWRK 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA5	NP_061975.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..175		29/156 (19%)
		Antp-type hexapeptide	176..181		0/4 (0%)
		Homeodomain	196..252	CDD:459649	27/55 (49%)
CG18599	NP_650701.1	Homeodomain	317..373	CDD:459649	27/55 (49%)